Science & Research Jobs in North Carolina with F-1 OPT Sponsorship
F-1 OPT science and research jobs in North Carolina are concentrated in the Research Triangle Park area, home to employers like RTI International, Biogen, and the National Institute of Environmental Health Sciences. Universities such as UNC-Chapel Hill, Duke, and NC State actively place OPT candidates in lab, research, and life sciences roles across the state.
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Career Category
Manufacturing
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX Batch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Associate Manufacturing – Downstream - Days (Multiple Positions)
What you will do
Let’s do this. Let’s change the world. In this dynamic role, you will be an Associate in the manufacturing organization at Amgen North Carolina (ANC). The essential position, which supports our critical 24/7 manufacturing operations, works a 12-hour 2-2-3 schedule from 5:45am to 6:15pm. Associates will be completing operations on the floor in our downstream area and will be responsible for the manufacturing of cGMP (Current Good Manufacturing Practices) drug substances.
With general direction, the Associate will support all floor operations in accordance with cGMP practices. As Amgen relies upon the regular attendance of staff members to meet legitimate business needs, staff must be able to work assigned 12-hour shift, including during inclement weather, some holidays and requested overtime in support of our 24/7 operations.
Compliance:
- Completes work in accordance with established cGMP procedures and policies (Standard Operating Procedures [SOPs], Manufacturing Procedures [MPs], Job Hazard Analysis [JHAs], Code of Federal Regulations [CFR]) with strict adherence to safety and compliance
- Assure proper gowning and aseptic techniques are always followed
Process/Equipment/Facilities:
- Perform hands-on downstream bio-tech operations (Column Chromatography, Tangential Flow Filtration among others) including set-up, cleaning, sanitization, monitoring of equipment and assigned area
- Run and monitor critical process tasks per assigned procedures
- Perform in-process sampling, operate analytical equipment, and complete process documentation (Electronic Batch Records [EBRs])
- Complete washroom activities: cleaning equipment, small to large scale, used in production activities
- Initiate and own manufacturing related process deviations
- Identify and escalate issues and concerns regarding daily routine functions related to process and tasks; may engage with team on potential solutions
- Perform documentation for assigned functions (i.e., equipment logs, EBRs)
- Collaborate as part of a cross-functional team (i.e., QA/QC, F&E (Facilities & Engineering), PPIC, Mfg., PD (Process Development), Regulatory, etc.) in completing production activities
- Maintain an organized, clean, and workable space
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The hard-working professionals we seek are team players with these qualifications.
Basic Qualifications:
- High School/GED + 2 years manufacturing and/or other regulated environment experience OR
- Associate’s Degree + 6 months manufacturing and/or other regulated environment experience OR
- Bachelor’s Degree
Preferred Qualifications:
- Completion of NC BioWorks Certification Program
- Experience in a regulated industry such as biotechnology or pharmaceutical
- Basic understanding and process experience in a cGMP manufacturing facility
- Excellent verbal and written communication
- Proficient Microsoft Office skills, and knowledge of other electronic systems such as EBR/MES, Delta V, and Electronic Quality Systems
- An ability to demonstrate desire and drive to learn and grow their understanding of operations and processes
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.
Apply now and make a lasting impact with the Amgen team.
Salary Range
75,618.00 USD - 89,473.00 USD
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Career Category
Manufacturing
Job Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Be part of Amgen's newest and most advanced drug substance manufacturing plant. When completed, the Amgen FleX Batch facility will combine the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility will not only feature the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it will also integrate sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.
Associate Manufacturing – Downstream - Days (Multiple Positions)
What you will do
Let’s do this. Let’s change the world. In this dynamic role, you will be an Associate in the manufacturing organization at Amgen North Carolina (ANC). The essential position, which supports our critical 24/7 manufacturing operations, works a 12-hour 2-2-3 schedule from 5:45am to 6:15pm. Associates will be completing operations on the floor in our downstream area and will be responsible for the manufacturing of cGMP (Current Good Manufacturing Practices) drug substances.
With general direction, the Associate will support all floor operations in accordance with cGMP practices. As Amgen relies upon the regular attendance of staff members to meet legitimate business needs, staff must be able to work assigned 12-hour shift, including during inclement weather, some holidays and requested overtime in support of our 24/7 operations.
Compliance:
- Completes work in accordance with established cGMP procedures and policies (Standard Operating Procedures [SOPs], Manufacturing Procedures [MPs], Job Hazard Analysis [JHAs], Code of Federal Regulations [CFR]) with strict adherence to safety and compliance
- Assure proper gowning and aseptic techniques are always followed
Process/Equipment/Facilities:
- Perform hands-on downstream bio-tech operations (Column Chromatography, Tangential Flow Filtration among others) including set-up, cleaning, sanitization, monitoring of equipment and assigned area
- Run and monitor critical process tasks per assigned procedures
- Perform in-process sampling, operate analytical equipment, and complete process documentation (Electronic Batch Records [EBRs])
- Complete washroom activities: cleaning equipment, small to large scale, used in production activities
- Initiate and own manufacturing related process deviations
- Identify and escalate issues and concerns regarding daily routine functions related to process and tasks; may engage with team on potential solutions
- Perform documentation for assigned functions (i.e., equipment logs, EBRs)
- Collaborate as part of a cross-functional team (i.e., QA/QC, F&E (Facilities & Engineering), PPIC, Mfg., PD (Process Development), Regulatory, etc.) in completing production activities
- Maintain an organized, clean, and workable space
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The hard-working professionals we seek are team players with these qualifications.
Basic Qualifications:
- High School/GED + 2 years manufacturing and/or other regulated environment experience OR
- Associate’s Degree + 6 months manufacturing and/or other regulated environment experience OR
- Bachelor’s Degree
Preferred Qualifications:
- Completion of NC BioWorks Certification Program
- Experience in a regulated industry such as biotechnology or pharmaceutical
- Basic understanding and process experience in a cGMP manufacturing facility
- Excellent verbal and written communication
- Proficient Microsoft Office skills, and knowledge of other electronic systems such as EBR/MES, Delta V, and Electronic Quality Systems
- An ability to demonstrate desire and drive to learn and grow their understanding of operations and processes
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.
Apply now and make a lasting impact with the Amgen team.
Salary Range
75,618.00 USD - 89,473.00 USD
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Job Roles in Science & Research in North Carolina
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Get Access To All JobsFrequently Asked Questions
Which science and research companies sponsor F-1 OPT visas in North Carolina?
North Carolina has a strong concentration of life sciences and research employers with F-1 OPT hiring history. RTI International, Biogen, Novo Nordisk, Labcorp, and the Research Triangle Institute are among the larger organizations. Federal research institutions within Research Triangle Park, including EPA and NIEHS labs, also host OPT candidates. Sponsorship is not guaranteed and varies by role, team budget, and the employer's familiarity with OPT authorization requirements.
Which cities in North Carolina have the most science and research F-1 OPT sponsorship jobs?
The Research Triangle, spanning Raleigh, Durham, and Chapel Hill, is by far the most active area for science and research OPT roles. Research Triangle Park itself sits at the center and hosts dozens of pharmaceutical, biotech, and environmental research employers. Charlotte has a smaller but growing life sciences presence. Outside these metros, opportunities are limited, so most OPT candidates in this field focus their search on the Triangle region.
What types of science and research roles typically qualify for F-1 OPT sponsorship in North Carolina?
Roles that directly align with your degree field are eligible for F-1 OPT. In North Carolina's science and research sector, this commonly includes research associate positions, laboratory technician roles, computational biology, environmental science, biostatistics, and clinical research coordination. STEM OPT extension eligibility applies to degrees in biology, chemistry, environmental science, biomedical engineering, and related fields, allowing a 24-month extension beyond the standard 12-month OPT period.
How do I find science and research F-1 OPT sponsorship jobs in North Carolina?
Migrate Mate is built specifically for international students and filters science and research F-1 OPT jobs in North Carolina by visa type, so you see only employers open to OPT candidates. Rather than sorting through general job boards and guessing at sponsorship willingness, Migrate Mate surfaces roles in biotech, life sciences, and research institutions across the Triangle and beyond that are actively hiring OPT holders in this field.
Are there any North Carolina-specific considerations for F-1 OPT in science and research?
North Carolina's Research Triangle Park is one of the largest science and research employment hubs in the country, which means many employers there have established processes for onboarding international OPT candidates. Life sciences and pharmaceutical companies in the state frequently work with international talent and are more likely to have HR familiarity with STEM OPT documentation. However, each employer's willingness to sponsor a future H-1B after OPT ends varies and should be confirmed directly during the hiring process.
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