Ionis Pharmaceuticals H-1B Visa Sponsorship Jobs USA
Ionis Pharmaceuticals sponsors H-1B visas for specialized roles in biotechnology and pharmaceutical research, including scientists, bioinformaticians, and clinical development professionals. While its H-1B program is selective rather than high-volume, Ionis actively recruits international talent for technically demanding positions requiring advanced expertise.
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DIRECTOR OF EPIDEMIOLOGY, MEDICAL EVIDENCE GENERATION
SUMMARY
The Director of Epidemiology is part of the Medical Evidence Generation (MEG) team and will serve as the lead for the Medical Affairs Epidemiology function, serving as a cross-TA epidemiology resource. The Director of Epidemiology provides scientific and strategic leadership for epidemiology activities across the product lifecycle in 20-30 different disease states, working closely with cross-functional teams including Medical Affairs, Clinical Development, HEOR, and Commercial teams. The Director of Epidemiology will provide epidemiology expertise and will design and conduct epidemiology studies/analyses and literature reviews to support organizational needs for epidemiology information across Ionis’ product portfolio and pipeline. This role will report to the Executive Director of Medical Evidence Generation.
Responsibilities:
- Serve as the principal epidemiology expert and resource for the organization.
- Responsible for the epidemiological approach and standards (governance, methodological guidance, quality expectations, and “source of truth” stewardship).
- Assess the long-term strategic impact of epidemiology information across the enterprise, as well as from individual functional perspectives.
- Serve as the hub of epidemiology data (cross-TA) for internal and external use, based on literature reviews or other sources.
- Maintain a database of all approved epidemiology estimates for disease states.
- Lead the design, execution, and interpretation of epidemiologic studies.
- Lead alignment with Medical Evidence Generation TA leads to ensure epidemiology activities are aligned with evidence strategy.
- Lead cross-functional teams including Medical Affairs, Clinical Development, HEOR, Corporate Communications, Investor Relations, and Commercial teams to ensure that epidemiology estimates are aligned with the overall business objectives.
- Review and approve study protocols, analysis plans, study reports, and manuscripts.
- Present epidemiology study results to internal and external stakeholders, including at scientific conferences, and other relevant forums.
- Stay up-to-date with the latest developments in epidemiology, observational research, registry methodologies, Phase 4 study design, and advanced analytical methods, and incorporate them in Ionis’ medical evidence generation activities.
REQUIREMENTS
- A PhD or Master’s degree in epidemiology, public health, or related field with at least 8 years of experience (PhD level) or 12 years of experience (Master’s level) in Epidemiology and/or Evidence Generation in the pharmaceutical industry.
- Demonstrated experience leading epidemiologic studies across multiple phases of the product lifecycle and in rare diseases.
- Strong knowledge of observational study designs, pharmacoepidemiology, genetic epidemiology, and real-world data sources (e.g., claims, EHRs, registries).
- Understanding of statistical methods for epidemiologic research.
- Strong analytical and problem-solving skills.
- Strong publication record.
- Experience in creation and management of a disease state epidemiology database.
- Excellent verbal and written communication and presentation skills.
- Ability to work collaboratively with cross-functional teams.
- Ability to lead without authority, specifically working with other functions to reach agreement.
- Ability to work independently and manage multiple projects simultaneously.
If you are passionate about using epidemiology methods to improve health outcomes for patients and have appropriate qualifications, we encourage you to apply for this exciting opportunity.
Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits
The pay scale for this position is $240,000 TO $260,000
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

DIRECTOR OF EPIDEMIOLOGY, MEDICAL EVIDENCE GENERATION
SUMMARY
The Director of Epidemiology is part of the Medical Evidence Generation (MEG) team and will serve as the lead for the Medical Affairs Epidemiology function, serving as a cross-TA epidemiology resource. The Director of Epidemiology provides scientific and strategic leadership for epidemiology activities across the product lifecycle in 20-30 different disease states, working closely with cross-functional teams including Medical Affairs, Clinical Development, HEOR, and Commercial teams. The Director of Epidemiology will provide epidemiology expertise and will design and conduct epidemiology studies/analyses and literature reviews to support organizational needs for epidemiology information across Ionis’ product portfolio and pipeline. This role will report to the Executive Director of Medical Evidence Generation.
Responsibilities:
- Serve as the principal epidemiology expert and resource for the organization.
- Responsible for the epidemiological approach and standards (governance, methodological guidance, quality expectations, and “source of truth” stewardship).
- Assess the long-term strategic impact of epidemiology information across the enterprise, as well as from individual functional perspectives.
- Serve as the hub of epidemiology data (cross-TA) for internal and external use, based on literature reviews or other sources.
- Maintain a database of all approved epidemiology estimates for disease states.
- Lead the design, execution, and interpretation of epidemiologic studies.
- Lead alignment with Medical Evidence Generation TA leads to ensure epidemiology activities are aligned with evidence strategy.
- Lead cross-functional teams including Medical Affairs, Clinical Development, HEOR, Corporate Communications, Investor Relations, and Commercial teams to ensure that epidemiology estimates are aligned with the overall business objectives.
- Review and approve study protocols, analysis plans, study reports, and manuscripts.
- Present epidemiology study results to internal and external stakeholders, including at scientific conferences, and other relevant forums.
- Stay up-to-date with the latest developments in epidemiology, observational research, registry methodologies, Phase 4 study design, and advanced analytical methods, and incorporate them in Ionis’ medical evidence generation activities.
REQUIREMENTS
- A PhD or Master’s degree in epidemiology, public health, or related field with at least 8 years of experience (PhD level) or 12 years of experience (Master’s level) in Epidemiology and/or Evidence Generation in the pharmaceutical industry.
- Demonstrated experience leading epidemiologic studies across multiple phases of the product lifecycle and in rare diseases.
- Strong knowledge of observational study designs, pharmacoepidemiology, genetic epidemiology, and real-world data sources (e.g., claims, EHRs, registries).
- Understanding of statistical methods for epidemiologic research.
- Strong analytical and problem-solving skills.
- Strong publication record.
- Experience in creation and management of a disease state epidemiology database.
- Excellent verbal and written communication and presentation skills.
- Ability to work collaboratively with cross-functional teams.
- Ability to lead without authority, specifically working with other functions to reach agreement.
- Ability to work independently and manage multiple projects simultaneously.
If you are passionate about using epidemiology methods to improve health outcomes for patients and have appropriate qualifications, we encourage you to apply for this exciting opportunity.
Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits
The pay scale for this position is $240,000 TO $260,000
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.
Job Roles at Ionis Pharmaceuticals
How to Get Visa Sponsorship in Ionis Pharmaceuticals H-1B Visa Sponsorship Jobs USA
Target roles that match your scientific specialization
Ionis focuses its H-1B sponsorship on roles requiring deep technical expertise, particularly in RNA-targeted drug discovery, clinical research, and bioinformatics. Aligning your application to these core research areas significantly improves your chances of sponsorship consideration.
Highlight advanced degrees in relevant fields
H-1B petitions at Ionis are strongest when supported by graduate-level degrees in molecular biology, biochemistry, pharmacology, or computational sciences. Clearly connecting your academic credentials to the specific role strengthens the specialty occupation case for your H-1B petition.
Engage early with Ionis recruiters about sponsorship
Because Ionis sponsors H-1B visas selectively, confirm sponsorship willingness during the initial recruiter conversation rather than after multiple interview rounds. This saves time and ensures both sides are aligned on immigration support before the process advances.
Understand Ionis's H-1B lottery timeline
H-1B petitions are subject to USCIS's annual lottery each April, with cap-subject cases taking effect October 1. Discuss timing with Ionis recruiters early so your start date expectations and their hiring needs align around this fixed USCIS calendar.
Use verified sponsorship data when searching
Not every Ionis job posting will mention H-1B explicitly. Migrate Mate surfaces verified sponsors so you can filter by real sponsorship history, helping you identify active openings at Ionis where visa support is a realistic outcome.
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Get Access To All JobsFrequently Asked Questions
Does Ionis Pharmaceuticals sponsor H-1B visas?
Yes, Ionis Pharmaceuticals sponsors H-1B visas. The company supports international candidates in specialized biotechnology and pharmaceutical roles, particularly in research, clinical development, and computational biology. Sponsorship is selective and typically reserved for positions requiring highly specific technical expertise that aligns with Ionis's RNA-targeted therapeutics pipeline.
Which roles and departments at Ionis Pharmaceuticals are most likely to receive H-1B sponsorship?
H-1B sponsorship at Ionis is most common in research and development functions, including molecular biology, antisense drug discovery, bioinformatics, clinical operations, and regulatory affairs. Roles requiring advanced graduate training in life sciences or computational fields are the strongest candidates for sponsorship, as they clearly meet the specialty occupation standard USCIS requires.
How do I navigate the H-1B application process at Ionis Pharmaceuticals?
Once Ionis extends an offer and confirms sponsorship, the company works with outside immigration counsel to file your H-1B petition. Your involvement includes providing education credentials, employment history, and supporting documentation. The petition is subject to the annual USCIS lottery in April, so your start date will typically align with the October 1 fiscal year cap date.
How long does the H-1B sponsorship process take at Ionis Pharmaceuticals?
The full H-1B timeline depends on when you receive your offer relative to the USCIS lottery window. If you miss the current cap cycle, you may wait up to a year before your petition can be filed. Premium processing, which USCIS offers for an additional fee, can accelerate approval to a few weeks once the petition is filed. Confirm timeline expectations with Ionis recruiters early.
How do I find open H-1B jobs at Ionis Pharmaceuticals?
Checking Ionis's careers page directly is a good starting point, but job listings don't always specify visa sponsorship availability. Migrate Mate lets you search verified H-1B sponsors and filter for active openings at companies like Ionis, so you can focus your applications on roles where sponsorship is a realistic outcome rather than an assumption.
What is the prevailing wage for H-1B jobs at Ionis Pharmaceuticals?
H-1B employers must pay at least the prevailing wage, which is determined when they file the Labor Condition Application with the Department of Labor. The rate is based on the role, location, and experience level, and ensures international hires are paid comparably to U.S. workers in the same position. You can look up prevailing wage rates for any occupation and location using the DOL's OFLC Wage Search tool.
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