Broad Institute Visa Sponsorship Jobs USA

General information

Location
Cambridge, MA
Ref #
45086
Job Family
Research
Date published
10/14/2026
Time Type
Full time
Pay Range
$104,000.00/yr - $145,333.00/yr

Description & Requirements

We are seeking a highly motivated and experienced Clinical Research Program Manager to lead the clinical research operations of a multidisciplinary program investigating inflammatory diseases and autoimmune disease. The program brings together investigators, clinicians, and research teams at the Broad Institute of MIT and Harvard and Massachusetts General Hospital.

The successful candidate will be a key contributor to the Broad Institute’s GaMBiT Initiative, an exciting initiative aimed at understanding how genetic factors increase disease risk and using that insight to accelerate the translation of genetic discoveries into therapeutics. The role requires close collaboration with colleagues at Massachusetts General Hospital, but we operate as a single, highly collaborative team and our cross-functional workflow means you will work from and engage with colleagues at both locations.

Our research seeks to understand why disease develops, why it progresses differently among individuals, why patients respond differently to therapy, and how these insights can be translated into better interventions for patients. By deeply characterizing patients and integrating clinical information with molecular and cellular measurements, we aim to identify mechanisms of disease, biomarkers of disease activity and treatment response, and ultimately new opportunities for prevention and treatment.

The Clinical Research Program Manager will connect patient-oriented research at Massachusetts General Hospital with genomic, immunologic, microbiome, metabolomic, single-cell, spatial, and computational research conducted across the collaborative program. The program includes prospective clinical cohorts and studies involving detailed clinical phenotyping and the collection of blood, tissue, stool, and other biospecimens for downstream molecular analysis.

This is a highly collaborative position at the interface of clinical research, scientific investigation, and research operations. The successful candidate will provide strategic and operational leadership across multiple clinical studies, supervise clinical research staff, and work closely with physicians, scientists, computational researchers, and institutional research teams to ensure that complex studies are executed rigorously and efficiently.

What You Will Do

• Manage the day-to-day operations of multiple clinical research studies in inflammatory and immune-mediated conditions.

• Work closely with principal investigators and multidisciplinary scientific teams to design, initiate, and implement human subjects research protocols and safety monitoring plans.

• Directly supervise, train, and support Clinical Research Coordinators and other study staff, including oversight of patient recruitment, medical-record abstraction, biospecimen acquisition and processing, and data quality.

• Coordinate study initiation and start-up activities and help ensure that regulatory, operational, and scientific requirements are addressed efficiently.

• Prepare and submit human subjects research protocols, amendments, continuing reviews, and related materials to the Institutional Review Board.

• Serve as a key liaison among investigators, study staff, the Institutional Review Board, sponsors and funding organizations, core laboratories, and collaborating research teams.

• Develop study operations manuals, standard operating procedures, Case Report Forms, and other study documentation.

• Establish project plans, forecast milestones, track progress, identify risks and dependencies, and ensure that projects remain aligned with scientific and leadership goals.

• Report study progress at investigator and project meetings and prepare study-related reports for research teams, funding organizations, and regulatory agencies.

• Oversee clinical research databases and workflows to ensure the quality, integrity, and appropriate handling of clinical and research data.

• Coordinate the collection, processing, tracking, and transfer of biospecimens used for genomic, transcriptomic, immunologic, microbiome, metabolomic, single-cell, spatial, and other molecular analyses.

• Facilitate approved sharing of data and biospecimens with collaborators in accordance with study protocols, Data Use Agreements, and institutional requirements.

• Connect clinical cohorts and biospecimens with experimental and computational research conducted across the collaborative program.

• Participate in the development and implementation of recruitment strategies for clinical studies.

• Oversee study budgets and associated research expenditures and coordinate subcontracts or other agreements with participating institutes.

How you work

• You bring exceptional organizational skills and attention to detail.

• Demonstrate analytical and problem-solving skills, makes independent, effective decisions and exercises sound judgment.

• Cross-functional collaborator with excellent interpersonal skills who builds productive working relationships with investigators, clinicians, research staff, institutional offices, and scientific collaborators.

Qualifications

• Bachelor’s degree in a related field with 7+ years of experience or Master’s degree in public health, biology, clinical research with 5+ years of experience managing clinical or human subjects research in an academic setting.

• Minimum 2 years of experience training and supervising a team of clinical research staff.

• Excellent strategic planning and project/program management skills, with demonstrated ability to lead complex projects from initiation through execution.

• Data management expertise, including configuration and management of complex clinical research databases. Experience collating requested subsets of data for clinical researchers.

• Proven track record of multi-study program leadership across clinical, scientific, computational, and administrative teams, orchestrating simultaneous project portfolios with proactive problem-solving, strict adherence to timelines and budget.

• Excellent written and verbal skills.

Preferred Experience

• Investigator initiated trials

• REDcap clinical research database

• PMP training or certification

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.