Senior Mainframe Systems Programmer Jobs in Maine
Senior Mainframe Systems Programmer jobs in Maine are open across Portland, Westbrook, and Augusta and other Maine metros, with employers like IDEXX Laboratories, MaineHealth, and CVS Health hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
We are seeking a highly skilled and intellectually driven Senior Systems Integration Engineer with a strong foundation in mathematical modeling, simulation, and data analysis to join a group of engineers and scientists focused on characterizing diagnostic products as they are integrated into instrument systems.
This role bridges rigorous quantitative methods with practical product development, supporting predictive modeling, experimental design, and data-driven decision making across the full IDEXX product lifecycle — from new product development through long-term product support. You will functionally break down, characterize, and model both assay and instrument components and processes to understand the relationship between key inputs and outputs to help develop products within an overall integrated system, ensuring end products meet requirements and perform their intended functions.
This is an on-site role to be based out of our Westbrook, ME corporate Headquarters.
What Will You Do?
- Develop and apply mathematical models and simulations to support product design, performance prediction, and requirements development — bringing a strategic mindset to translate complex technical problems into scalable solutions.
- Build and maintain predictive models and forecasting frameworks to inform product strategy and lifecycle decisions, demonstrating decision quality and the ability to manage complexity in ambiguous, data-rich environments.
- Design and oversee/execute experiments, applying statistical and computational methods to extract actionable insights from large-scale datasets — driving results with rigor and resourcefulness.
- Translate raw data into meaningful information that shapes product and business decisions, exhibiting a strong customer focus and the ability to persuade diverse audiences through clear, evidence-based storytelling.
- Contribute to product requirements development by connecting quantitative analysis to customer and organizational needs, exercising organizational savvy and a global perspective.
- Conceptualize and evaluate technical feasibility of new product concepts and major hardware changes to existing products.
- Partner with cross-functional teams across engineering, science, and commercial functions, fostering a culture that collaborates, drives engagement, and values differences.
- Maintain clear, well-organized documentation of models, methodologies, and results, ensuring accountability and supporting long-term knowledge continuity.
What Do You Need to Succeed?
- A degree in Physics, Physical Chemistry, Analytical Chemistry, Chemistry, Chemical Engineering, Applied Engineering, Applied Mathematics, or a related discipline. Candidates should possess a Bachelor’s with 5 years’ experience, Master's with 3 years’ experience, or PhD with 2 years’ experience.
- Proficiency in one or more of the following is required: Python, JMP, Mathematica, R, or SAS.
- Hands-on experience with robotics, instrumentation design, or hardware/software integration — from concept through implementation — is preferred, particularly where such systems were developed or adapted to support analytical or diagnostic workflows.
- Ability to characterize and model systems by breaking them down into their component parts, mapping out how each function will work within the overall system to ensure products will operate to requirements and as intended.
- Experience with big data platforms such as Snowflake or Amazon S3 is desired.
- Solid understanding of biology, chemistry, and engineering and how these concepts interact within a system.
- Experience in all phases of development and product support project life cycles.
- The courage to challenge assumptions, advocate for data-driven conclusions, and engage constructively across all levels of the organization.
- Demonstrated ability to manage ambiguity — comfortable operating in evolving problem spaces where requirements and priorities shift.
- Strong verbal, written, and interpersonal communication skills, with the ability to present complex findings to both technical and non-technical audiences.
What you can expect from us:
- Salary range starting at $105,000 based on experience
- Opportunity for annual cash bonus
- Health / Dental / Vision Benefits Day-One
- 5% matching 401k
- Additional benefits including but not limited to financial support, pet insurance, mental health resources, volunteer paid days off, employee stock program, foundation donation matching, and much more
If you’re looking for a role that’ll challenge you, offer a variety of work and learning, while helping an amazing industry, we’d love to hear from you!
Why IDEXX?
We’re proud of the work we do, because our work matters. An innovation leader in every industry we serve since 1983, our team members help pet owners worldwide keep their companion animals healthy and happy, ensure safe drinking water for billions, and help farmers protect livestock and poultry from disease.
We have customers in over 175 countries and a collaborative global workforce. Our culture embraces challenges and encourages learning and discovery. At IDEXX, you’ll be supported by competitive compensation, incentives, and benefits while enjoying purposeful work that drives improvement.
If meaningful work and a sense of purpose are at the top of your list, you’ll find it here. Let’s pursue what matters together.
About the job location:
If you’re thinking about relocating for this role, here are a few things to know about living in Maine (often called “Vacationland”). The Westbrook, ME area provides great access to active downtown areas and the outdoors, with the coast and numerous mountains and hiking trails nearby. You’ll also find several large companies like ours in the area, creating a vibrant work culture.
IDEXX values a diverse workforce and workplace and strongly encourages women, people of color, LGBTQ+ individuals, people with disabilities, members of ethnic minorities, foreign-born residents, and veterans to apply.
IDEXX is an equal opportunity employer. Applicants will not be discriminated against because of race, color, creed, sex, sexual orientation, gender identity or expression, age, religion, national origin, citizenship status, disability, ancestry, marital status, veteran status, medical condition, or any protected category prohibited by local, state, or federal laws.
While we appreciate our staffing partners, we are unable to accept unsolicited agency resumes.
See All 131+ Senior Mainframe Systems Programmer Jobs in Maine
Find roles in Maine that match your experience and apply in just a few clicks.
Find JobsSenior Mainframe Systems Programmer Jobs by City in Maine
Where Maine roles are concentrated, by current openings.
Senior Mainframe Systems Programmer Job Market in Maine
A snapshot from current Maine openings, updated as new roles post.
Who's Hiring
- IDEXX Laboratories25

- MaineHealth11

- CVS Health8

- Tyler Technologies8

- The Jackson Laboratory7

Top Industries Hiring
- Healthcare & Medical Services26
- Animal Care & Pet Services25
- Consulting & Professional Services19
- Technology & Software17
- Construction & Real Estate9
What Maine Employers Look For
The qualifications that appear most often in senior mainframe systems programmer jobs across Maine.
- 5 or more years of hands-on z/OS systems programming experience in a production environment
- Proficiency with IBM system software installation and maintenance using SMP/E
- Experience configuring and supporting JES2 or JES3, VTAM, and TCP/IP on z/OS
- Working knowledge of RACF, ACF2, or Top Secret for mainframe security administration
- Familiarity with DFSMS, DASD management, and storage subsystem configuration
- Bachelor's degree in computer science, information systems, or a related technical field
Senior Mainframe Systems Programmer Jobs in Maine: Frequently Asked Questions
How many senior mainframe systems programmer jobs are there in Maine?
There are 131+ senior mainframe systems programmer openings in Maine on Migrate Mate as of June 2026, with the most roles in Portland, Westbrook, and Augusta. New positions post regularly as employers across Maine hire.
How much do senior mainframe systems programmers make in Maine?
Senior mainframe systems programmers in Maine earn a median of about $101,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $72,930 for the lowest 10% to over $191,670 for the top 10%. Pay rises with experience, specialty, and employer.
Which Maine cities have the most senior mainframe systems programmer jobs?
Portland, Westbrook, and Augusta have the most senior mainframe systems programmer openings in Maine right now, with additional roles spread across smaller metros statewide.
Which companies hire senior mainframe systems programmers in Maine?
Employers hiring senior mainframe systems programmers in Maine include IDEXX Laboratories, MaineHealth, and CVS Health, based on current listings on Migrate Mate as of June 2026.
Are there remote senior mainframe systems programmer jobs in Maine?
Yes. About 29% of senior mainframe systems programmer openings tied to Maine are remote or hybrid as of June 2026. The rest are on-site roles based in Maine metros.
How do I apply for senior mainframe systems programmer jobs in Maine?
You can apply to senior mainframe systems programmer jobs in Maine directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Maine location, then apply to each one that fits.
See All 131+ Senior Mainframe Systems Programmer Jobs in Maine
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