AI ML Engineer Jobs in San Francisco, CA
AI ML Engineer jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with strong demand across enterprise software, biotech, and fintech. Employers posting right now include Lila Sciences, Genentech, and Uber. Scan the live roles below and apply to whichever ones fit.
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Our Mission
Rebuild how the world works, to make institutions work better for the people they serve.
About Brain Co.
Brain Co. builds AI-native operating systems for large, regulated institutions. Each system is built for a specific industry, powered by agents that push real workflows forward. Underneath it all is Atlas, our proprietary platform that keeps customers in control, secure by design, and never locked into one model.
Why Now
Brain Co. is entering its next phase of production deployments on a national scale with an elite team built from Palantir, Google, Meta, and Nvidia, and a growing footprint across government, insurance, health, and financial services.
Joining now means shaping both the company and a new category of applied AI. Every project here ships to production and is expected to create measurable customer value and impact.
You'll work alongside exceptional peers on some of the hardest problems in applied AI. It’s the kind of work you'll still be proud of in ten years from now.
About the Role:
As an AI/ML Engineer Intern, you’ll work alongside experienced engineers and researchers to help design, build, and deploy machine learning systems that solve high-impact problems in healthcare, government, and energy.
This internship is designed for current undergraduate students, specifically juniors and seniors graduating no later than June 2028, who want hands-on experience applying modern AI techniques, especially large language models, to real-world challenges. You’ll gain exposure to the full ML lifecycle while receiving mentorship and ownership over meaningful projects.
What You’ll Do
Assist in designing and deploying LLM-powered applications to automate complex, real-world workflows
Build and improve data pipelines and support model training, evaluation, and optimization
Work with structured and unstructured data (e.g., text, documents, logs)
Help prepare models and systems for production deployment and monitoring
Collaborate closely with senior engineers, AI researchers, and product teams
Learn best practices through code reviews, design discussions, and hands-on mentorship
Gain exposure to customer-facing and real-world constraints, including working with public-sector institutions
You Might Be a Good Fit If You
Are a current undergraduate students, specifically juniors and seniors graduating no later than June 2028, pursuing a degree in Computer Science, Machine Learning, Data Science, or a related field
Have experience programming in Python
Have coursework or project experience in machine learning or AI
Have exposure to or interest in large language models and GenAI applications (e.g., agents, RAG, reasoning workflows)
Have used or are eager to learn frameworks such as PyTorch, JAX, or TensorFlow
Have strong fundamentals in data structures and algorithms
Are curious, proactive, and excited to learn quickly in a fast-paced environmentEnjoy owning problems end-to-end with guidance and support
Internship Details & Benefits
Dates: May 31, 2027 - Aug 6, 2027 or July 5, 2027 - September 10, 2027
Competitive internship compensation
Hands-on mentorship from experienced AI engineers and researchers
Opportunity to work on real production systems used globally
Potential return-offer consideration for future internships or full-time roles
Daily lunches (if onsite)
See All 94 AI ML Engineer Jobs in San Francisco
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Find AI ML Engineer JobsAI ML Engineer Job Market in San Francisco
Who's Hiring
- Lila Sciences14

- Genentech10

- Uber7

- BRAIN7

- Achira7A
Top Industries Hiring
- Technology & Software
- Electronics & Hardware
- Automotive
- Banking & Financial Services
AI ML Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a ai ml engineer job in San Francisco?
Focus on San Francisco's dominant hiring clusters: enterprise software companies in SoMa, biotech and life sciences firms in Mission Bay, and fintech players in the Financial District. Hands-on experience with large language models, MLOps pipelines, or production model deployment gives candidates a clear edge here. Contributing to open-source ML projects and attending local meetups in the Bay Area tech community also puts your work in front of the hiring teams that matter most.
Which companies hire ai ml engineers in San Francisco?
San Francisco ai ml engineer roles are posted by Lila Sciences, Genentech, and Uber and others right now, based on current listings on Migrate Mate as of November 2026. The city draws a wide mix of well-funded startups, established tech platforms, and healthcare and fintech companies that have made AI infrastructure a core part of their product teams.
Are there remote ai ml engineer jobs in San Francisco?
Yes, ai ml engineer work is well-suited to remote and hybrid arrangements since most of the role involves coding, model training, and data work that does not require a physical presence. About 71% of ai ml engineer openings tied to San Francisco are remote or hybrid as of November 2026, reflecting how tech-forward local employers approach this function. Research, experimentation, and evaluation tasks tend to be the most remote-friendly parts of the role in San Francisco.
How can I get a ai ml engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is through a junior ML engineer or data scientist role at a growth-stage startup in SoMa or the broader Bay Area tech ecosystem, where smaller teams are more open to candidates still building production experience. Internships at biotech firms in Mission Bay or AI-focused product teams at mid-size software companies are strong lateral moves. A portfolio of deployed model projects on GitHub, even at small scale, carries significant weight with San Francisco hiring managers reviewing early-career candidates.
Which industries hire the most ai ml engineers in San Francisco?
Most ai ml engineer openings in San Francisco sit in Technology & Software, Electronics & Hardware, and Automotive, per current listings on Migrate Mate as of November 2026. San Francisco's role as the global center of AI investment means these sectors compete intensely for ML talent, driving consistent demand across both established companies and well-capitalized startups.
Related Jobs in California
See All 94 AI ML Engineer Jobs in San Francisco
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