AI ML Engineer Jobs in San Francisco, CA

AI ML Engineer jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with strong demand across enterprise software, biotech, and fintech. Employers posting right now include Genentech, Lila Sciences, and Uber. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles101+
Top employerGenentech
Work type50% Hybrid
Top credentialDoctoral degree in Computer Science
Companies hiring15

Showing 5 of 101+ AI ML Engineer jobs

Atlassian
Senior Machine Learning Engineer, AI-Native Evaluation & Search
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Atlassian
Added 2d ago
Senior Machine Learning Engineer, AI-Native Evaluation & Search
Atlassian
San Francisco, California
Engineering (Non-Software)
Manufacturing Operations
Quality Assurance & Testing (QA Testing)
Specialized Engineering
$171k - $269k/yr
Remote (US)
Master's degree
10,000+

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Lila Sciences
Senior ML Scientist, AI for Protein Engineering
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Lila Sciences
Added 3d ago
Senior ML Scientist, AI for Protein Engineering
Lila Sciences
San Francisco, California
Customer Support
Sales
Technical Product & Program Management
$268k - $358k/yr
Doctoral degree in Computer Science

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Lila Sciences
ML Scientist I/II, AI for Protein Engineering
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Lila Sciences
Added 3d ago
ML Scientist I/II, AI for Protein Engineering
Lila Sciences
San Francisco, California
Biotech & Life Sciences
Clinical Trials & Medical Research
Data Science
Research & Academia
$176k - $304k/yr
Doctoral degree in Computer Science

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Amazon Web Services
Delivery Consultant – AI ML, Professional Services, AWSI HCLS
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Amazon Web Services
Added 3d ago
Delivery Consultant – AI ML, Professional Services, AWSI HCLS
Amazon Web Services
San Francisco, California
Business Operations
Program Management
Project Management
$125k - $204k/yr
AWS Certification

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Lila Sciences
Machine Learning Engineer I/II, Applied AI
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Lila Sciences
Added 1w ago
Machine Learning Engineer I/II, Applied AI
Lila Sciences
San Francisco, California
Engineering (Non-Software)
Mechanical Engineering
Product Management
$116k - $170k/yr

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See All 101+ AI ML Engineer Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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AI ML Engineer Job Market in San Francisco

Who's Hiring

  • Genentech
    Genentech14
  • Lila Sciences
    Lila Sciences14
  • Uber
    Uber10
  • A
    Achira10
  • Samsara
    Samsara5

Top Industries Hiring

  • Technology & Software10
  • Electronics & Hardware10
  • Automotive5
  • Banking & Financial Services5
  • Healthcare & Medical Services5

AI ML Engineer Jobs in San Francisco: Frequently Asked Questions

How do I get a ai ml engineer job in San Francisco?

Focus on San Francisco's dominant hiring clusters: enterprise software companies in SoMa, biotech and life sciences firms in Mission Bay, and fintech players in the Financial District. Hands-on experience with large language models, MLOps pipelines, or production model deployment gives candidates a clear edge here. Contributing to open-source ML projects and attending local meetups in the Bay Area tech community also puts your work in front of the hiring teams that matter most.

Which companies hire ai ml engineers in San Francisco?

San Francisco ai ml engineer roles are posted by Genentech, Lila Sciences, and Uber and others right now, based on current listings on Migrate Mate as of September 2026. The city draws a wide mix of well-funded startups, established tech platforms, and healthcare and fintech companies that have made AI infrastructure a core part of their product teams.

Are there remote ai ml engineer jobs in San Francisco?

Yes, ai ml engineer work is well-suited to remote and hybrid arrangements since most of the role involves coding, model training, and data work that does not require a physical presence. About 75% of ai ml engineer openings tied to San Francisco are remote or hybrid as of September 2026, reflecting how tech-forward local employers approach this function. Research, experimentation, and evaluation tasks tend to be the most remote-friendly parts of the role in San Francisco.

How can I get a ai ml engineer job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is through a junior ML engineer or data scientist role at a growth-stage startup in SoMa or the broader Bay Area tech ecosystem, where smaller teams are more open to candidates still building production experience. Internships at biotech firms in Mission Bay or AI-focused product teams at mid-size software companies are strong lateral moves. A portfolio of deployed model projects on GitHub, even at small scale, carries significant weight with San Francisco hiring managers reviewing early-career candidates.

Which industries hire the most ai ml engineers in San Francisco?

Most ai ml engineer openings in San Francisco sit in Technology & Software, Electronics & Hardware, and Automotive, per current listings on Migrate Mate as of September 2026. San Francisco's role as the global center of AI investment means these sectors compete intensely for ML talent, driving consistent demand across both established companies and well-capitalized startups.

See All 101+ AI ML Engineer Jobs in San Francisco

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