Senior Level Applied AI Engineer Jobs

Senior level applied ai engineer jobs put experienced practitioners in charge of system architecture, model deployment decisions, and the applied research or engineering teams that build production-ready AI solutions. Openings cover 30% remote and hybrid arrangements across Technology & Software, Science & Research, and Insurance, with employers like Articul8, Anthropic, and JPMorganChase hiring at this level now.

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Overview

Open roles45
Top stateCalifornia
Top employerArticul8
Top citySan Francisco, CA
Work type70% On-site
Top industryTechnology

Showing 5 of 45+ Senior Level Applied AI Engineer jobs

Aflac
Data Mod & Applied AI Lead
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Aflac
Added 2d ago
Data Mod & Applied AI Lead
Aflac
Columbus, Georgia
Software Engineering
Data Science & Analytics
Data Engineering
Technical Product & Program Management
Project & Program Management
AI (Artificial Intelligence)
Data Science
Technical Program Management
Project Management
$140k - $200k/yr
Hybrid
Bachelor's
5,001-10,000

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Anthropic
Applied AI, Research Engineer
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Anthropic
Added 1w ago
Applied AI, Research Engineer
Anthropic
New York, New York
Software Engineering
Data Science & Analytics
Technical Product & Program Management
Data Science
Technical Program Management
$300k - $400k/yr
Hybrid
Bachelor's

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Eli Lilly
Director / Senior Director – Cheminformatics and Applied AI
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Eli Lilly
Added 2w ago
Director / Senior Director – Cheminformatics and Applied AI
Eli Lilly
Boston, Massachusetts
AI (Artificial Intelligence)
Data Analytics
Data Science
$194k - $308k/yr
Bachelor of Science
10,000+

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Anthropic
Strategy & Operations, Applied AI
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Anthropic
Added 2w ago
Strategy & Operations, Applied AI
Anthropic
New York, New York
Strategy & Corporate Development
Partnerships & Business Development
Project & Program Management
Consulting & Professional Services
Business Strategy
Business Development
Revenue Operations & Enablement
$270k/yr
On-Site
Bachelor's

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Amazon.com
Senior Applied AI Partner Solutions Architect
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Amazon.com
Added 3w ago
Senior Applied AI Partner Solutions Architect
Amazon.com
Austin, Texas
Solutions Engineering & Architecture
Technical Product & Program Management
Partnerships & Business Development
Cloud & DevOps
Technical Program Management
Business Development
Cloud Engineering
$154k - $208k/yr
On-Site
None
10,000+

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Senior Level Applied AI Engineer Job Market

Who's Hiring

Articul8
Articul84 open roles
Anthropic
Anthropic4 open roles
JPMorganChase
JPMorganChase4 open roles

Top Industries Hiring

  • Technology & Software20
  • Science & Research8
  • Insurance3
  • Electronics & Hardware3
  • Banking & Financial Services3

Senior Level Applied AI Engineer Jobs: Frequently Asked Questions

How do I get a senior level applied ai engineer job?

Employers hiring at this level look for candidates who have owned end-to-end ML pipelines in production, not just contributed to them. Demonstrating that you have made architectural decisions, debugged systems under real constraints, and mentored junior engineers sets you apart. A portfolio of deployed models with measurable business impact carries more weight than credentials alone at the senior level.

Which companies hire senior level applied ai engineers?

Companies hiring senior level applied ai engineers right now include Articul8, Anthropic, and JPMorganChase, based on current listings on Migrate Mate as of September 2026. Hiring at this level comes from a mix of large technology firms scaling AI infrastructure, enterprise companies embedding AI into core products, and well-funded startups building specialized model applications.

Are there remote senior level applied ai engineer jobs?

Yes, remote and hybrid opportunities are widely available at this level. About 30% of senior level applied ai engineer openings are remote or hybrid as of September 2026, reflecting how many organizations treat senior AI engineers as distributed contributors who can lead effectively without being on-site every day.

What makes an applied ai engineer role senior level?

Senior level applied ai engineer roles are defined by scope and ownership. You are expected to design systems rather than implement tickets, evaluate tradeoffs across modeling approaches, and represent technical direction in cross-functional conversations. Mentoring junior engineers and reviewing the work of others is a core expectation, not an occasional add-on. The role requires independent judgment on ambiguous problems, not just execution of defined tasks.

Which industries hire the most senior level applied ai engineers?

Senior level applied ai engineer roles concentrate in Technology & Software, Science & Research, and Insurance, based on current listings on Migrate Mate as of September 2026. These sectors drive hiring at this level because they are integrating AI into high-stakes, large-scale systems where experienced engineers who can own outcomes and lead technical decisions are essential.