BigHat Biosciences Jobs Hiring Now
BigHat Biosciences is hiring for 7 open roles on Migrate Mate as of July 16, 2026, concentrated in biotech & life sciences and content & communications, with listed salaries up to about $165,000. Migrate Mate updates BigHat Biosciences's live openings daily. BigHat Biosciences is a biotechnology company that applies machine learning to antibody design and engineering, developing therapeutics for patients with serious diseases.
Find BigHat Biosciences JobsOverview
BigHat Biosciences hiring data on Migrate Mate, as of July 16, 2026.
- Open jobs
- 7
- Top team
- Biotech & Life Sciences
- Seniority
- Across all levels
- Work type
- 0% remote or hybrid
- Top location
- San Mateo
- Salary range
- $75,000–$165,000
Listed salaries for BigHat Biosciences roles on Migrate Mate range from about $75,000 to $165,000 per year across 7 open roles, as of July 16, 2026.
Open Roles at BigHat Biosciences
Showing 7 of 7+ BigHat Biosciences jobs
Senior Software Engineer
We won't show you this job again
Added 3w ago
BigHat Biosciences
Senior Software Engineer
San Mateo, California
Added 3w ago
Research Associate I, CFPS Production
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Added 1mo ago
BigHat Biosciences
Research Associate I, CFPS Production
San Mateo, California
Added 1mo ago
Scientist II, Developability
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Added 1mo ago
BigHat Biosciences
Scientist II, Developability
San Mateo, California
Added 1mo ago
Associate Scientist, Display Technologies
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Added 1mo ago
BigHat Biosciences
Associate Scientist, Display Technologies
San Mateo, California
Added 1mo ago
Scientist II, Cell Line Engineering
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Added 1mo ago
BigHat Biosciences
Scientist II, Cell Line Engineering
San Mateo, California
Added 1mo ago
Senior Research Associate, Discovery Medicine
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Added 1mo ago
BigHat Biosciences
Senior Research Associate, Discovery Medicine
San Mateo, California
Added 1mo ago
Research Associate I/II, Production
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Added 3mo ago
BigHat Biosciences
Research Associate I/II, Production
San Mateo, California
Added 3mo ago
Added 3w ago
Senior Software Engineer
BigHat Biosciences·San Mateo, California
Job functions:
Job Description
Description
The role: BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject-matter expert, lead epics end-to-end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.
This role is leveled as Senior Software Engineer I. At this level, you operate as a subject-matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
- At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.
Key Responsibilities
- Lead projects end-to-end, from PRD through implementation, testing, release, and validation against the customer success metric.
- Own one or more major areas of BigHat's internally developed, cloud-based platform as a subject-matter expert, and serve as a cross-team and cross-org resource for those areas.
- Take on net-new, 0-to-1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.
- Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real-world lab workflows into reliable software, and to iterate on success metrics.
- Operate and run engineering processes: PRD reviews, stand-ups, PR approvals, and other team ceremonies.
- Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.
- Drive technical depth across the codebase, infrastructure, and systems, and actively improve the design and architectural principles the team works within.
- Design and build high-quality software across front-end (UI/UX) and back-end systems, with system-level expertise in the databases, AWS services, runtimes, and processes that underpin them.
- Lead and review technical designs and PRDs; contribute architectural direction and surface risks and tradeoffs early.
- Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.
- Run code reviews as a routine approver, providing thoughtful, high-leverage feedback that develops other engineers.
- Diagnose and resolve complex issues across production and development environments, including across system and environment boundaries.
- Improve internal engineering practices, documentation, tooling, and architecture; help set and transmit appropriate urgency in partnership with engineering leaders.
Skills Knowledge and Expertise
- You have a track record of owning features and epics end to end in a production software environment.
- You are an SME in at least one significant technical area and are reaching to master new ones.
- You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.
- You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.
- You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.
- You are motivated by building software that supports real users doing complex, high-stakes scientific work.
- You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.
- 7+ years of professional software engineering experience building and owning production systems, including demonstrated end-to-end ownership of features or epics, OR
- 5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.
Depth in several of the following, with the ability to make and improve system- and architecture-level decisions:
- TypeScript, React, Material-UI, Vega
- Python 3, SQLAlchemy
- RESTful API design
- AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
- Relational databases (e.g., PostgreSQL), including schema and query design
- Pandas
- PyTorch or other ML frameworks (nice to have, not required)
Total Rewards
The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
- Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
- Dental, and vision coverage through Guardian
- Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
- 401(k) with company match
- DTO, two weeks of company-wide shutdown, and 12 company holidays
- Paid parental leave
About BigHat Biosciences
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.
BigHat Biosciences
Senior Software Engineer
San Mateo, California
Added 3w ago
Job functions:
Job Description
Description
The role: BigHat Biosciences is looking for a Senior Software Engineer to join our engineering team. This role is for experienced engineers ready to own a significant area of our platform as a subject-matter expert, lead epics end-to-end, and shape the architecture and engineering practices that support the design, build, and testing of therapeutic antibodies at scale. You will work closely with engineers, product partners, and laboratory scientists to build and evolve the internal software systems at the center of our science.
This role is leveled as Senior Software Engineer I. At this level, you operate as a subject-matter expert in your area, working with a high degree of independence and regularly leading epics. Candidates with prior experience in biotech, life sciences, or scientific software may be considered with fewer total years of software engineering experience.
- At BigHat we believe in titles that commensurate with skill set, relative organizational impact, and value contribution; more experienced candidates are encouraged to apply, with the understanding that responsibilities and title would adjust as appropriate.
Key Responsibilities
- Lead projects end-to-end, from PRD through implementation, testing, release, and validation against the customer success metric.
- Own one or more major areas of BigHat's internally developed, cloud-based platform as a subject-matter expert, and serve as a cross-team and cross-org resource for those areas.
- Take on net-new, 0-to-1 work from specification, designing interactions between features and the infrastructure that supports them, and producing novel solutions where existing patterns fall short.
- Collaborate with, and increasingly manage, the relationship with scientists and product owners to translate real-world lab workflows into reliable software, and to iterate on success metrics.
- Operate and run engineering processes: PRD reviews, stand-ups, PR approvals, and other team ceremonies.
- Own the quality and outcomes of your work and your epics, including debugging, test failures, and production issues, anticipating next steps and owning the trajectory of major features.
- Drive technical depth across the codebase, infrastructure, and systems, and actively improve the design and architectural principles the team works within.
- Design and build high-quality software across front-end (UI/UX) and back-end systems, with system-level expertise in the databases, AWS services, runtimes, and processes that underpin them.
- Lead and review technical designs and PRDs; contribute architectural direction and surface risks and tradeoffs early.
- Write, maintain, and raise the bar on automated testing to ensure correctness, reliability, and maintainability.
- Run code reviews as a routine approver, providing thoughtful, high-leverage feedback that develops other engineers.
- Diagnose and resolve complex issues across production and development environments, including across system and environment boundaries.
- Improve internal engineering practices, documentation, tooling, and architecture; help set and transmit appropriate urgency in partnership with engineering leaders.
Skills Knowledge and Expertise
- You have a track record of owning features and epics end to end in a production software environment.
- You are an SME in at least one significant technical area and are reaching to master new ones.
- You work highly independently and initiate the collaborations needed to deliver work that bridges many parts of the codebase.
- You balance development, architecture, and process effectively, and help the team prioritize where effort yields the most impact.
- You communicate clearly about progress, risks, and tradeoffs, and your own outcomes, following issues through to resolution and validating that you've met the customer's needs.
- You are motivated by building software that supports real users doing complex, high-stakes scientific work.
- You adapt well as priorities and focus areas shift, and you collaborate effectively with engineers inside and outside your direct team.
- 7+ years of professional software engineering experience building and owning production systems, including demonstrated end-to-end ownership of features or epics, OR
- 5+ years of professional software engineering experience with prior experience in biotech, life sciences, laboratory environments, or scientific software, where domain knowledge meaningfully accelerates impact.
Depth in several of the following, with the ability to make and improve system- and architecture-level decisions:
- TypeScript, React, Material-UI, Vega
- Python 3, SQLAlchemy
- RESTful API design
- AWS (CDK, Lambda, Step Functions, ECS/Batch, Fargate, API Gateway, Athena)
- Relational databases (e.g., PostgreSQL), including schema and query design
- Pandas
- PyTorch or other ML frameworks (nice to have, not required)
Total Rewards
The salary estimated for this position is $198,00 - $215,000 + bonus + options + benefits. Compensation will vary depending on job-related knowledge, skills, and experience. Actual compensation will be confirmed in writing at the time of the offer.
What BigHat Offers:
- Range of health insurance plan options through Anthem and Kaiser (monthly credit if benefit waived)
- Dental, and vision coverage through Guardian
- Additional well-being benefits through Nayya, OneMedical, Wagmo, Rula, and more
- 401(k) with company match
- DTO, two weeks of company-wide shutdown, and 12 company holidays
- Paid parental leave
About BigHat Biosciences
BigHat Biosciences designs safer, more effective biologic therapies for patients using machine learning and synthetic biology.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat integrates a wet lab for high-speed characterization with machine learning technologies to guide the search for better antibodies. We apply these design capabilities to develop new generations of safer and more effective treatments for patients suffering from today’s most challenging diseases.
BigHat is a Series B biotech outside San Francisco with a team-oriented, inclusive, and family-friendly culture. Our broad pipeline of wholly-owned and partnered therapeutic programs span many disparate indications with high unmet need, such as cancer, inflammation, and infectious disease. BigHat has raised >$100M from top investors, including Section 32, a16z, and 8VC.
Job Roles at BigHat Biosciences
Biotech & Life Sciences5 jobs
Content & Communications1 jobs
Civil & Structural Engineering1 jobs
Working at BigHat Biosciences
BigHat Biosciences's 7 open roles are across all levels, and about 0% are remote or hybrid. The most active teams are biotech & life sciences, content & communications, and civil & structural engineering. BigHat Biosciences is a biotechnology company combining machine learning with protein engineering to design and optimize antibody therapeutics. The company works across discovery, cell line engineering, and production, with teams spanning wet-lab research and software development. Most BigHat Biosciences roles are based in San Mateo.
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Browse jobs by roleBigHat Biosciences Jobs: Frequently Asked Questions
How many jobs is BigHat Biosciences hiring for right now?
BigHat Biosciences is hiring for 7 open roles on Migrate Mate as of July 16, 2026, updated daily, concentrated in biotech & life sciences and content & communications. Roles span wet-lab research, cell line engineering, production, and software engineering across multiple seniority levels.
What kinds of roles does BigHat Biosciences hire for?
The most active teams are biotech & life sciences, content & communications, and civil & structural engineering. BigHat Biosciences posts roles in discovery research, cell-free protein synthesis, cell line engineering, display technologies, developability science, and software engineering. Most postings are across all levels, covering both bench scientists and computational contributors.
Are BigHat Biosciences jobs remote or in-person?
Mostly on-site. About 0% of BigHat Biosciences's open roles on Migrate Mate are remote or hybrid as of July 16, 2026, with the rest based in San Mateo. Each BigHat Biosciences listing shows its work location so you can filter before applying.
How do I apply to a job at BigHat Biosciences?
Find a BigHat Biosciences role on Migrate Mate, then follow the listing through to BigHat Biosciences' own careers page to submit your application directly. BigHat Biosciences manages its own hiring process, including application review, interviews, and offers.
What do BigHat Biosciences jobs pay?
Listed salaries for BigHat Biosciences roles on Migrate Mate range from about $75,000 to $165,000 per year as of July 16, 2026, with most postings at across all levels. Exact pay is set by BigHat Biosciences and shown on each listing.
Does BigHat Biosciences hire entry-level?
Most of BigHat Biosciences's open roles on Migrate Mate are across all levels as of July 16, 2026. Check individual BigHat Biosciences listings for stated experience requirements.
Where is BigHat Biosciences hiring?
Most BigHat Biosciences roles are based in San Mateo, and about 0% offer remote or hybrid work as of July 16, 2026. Migrate Mate shows the location on each listing.