Manifold Bio Jobs Hiring Now
Manifold Bio is hiring for 8 open roles on Migrate Mate as of July 16, 2026, concentrated in AI (Artificial Intelligence) and business strategy, with listed salaries up to about $275,000. Migrate Mate updates Manifold Bio's live openings daily. Manifold Bio is a biotechnology company focused on protein engineering and AI-driven drug development, working at the intersection of computational biology and laboratory science.
Find Manifold Bio JobsOverview
Manifold Bio hiring data on Migrate Mate, as of July 16, 2026.
- Open jobs
- 8
- Top team
- AI (Artificial Intelligence)
- Seniority
- Across all levels
- Work type
- 0% remote or hybrid
- Top location
- Boston
- Salary range
- $70,000–$275,000
Listed salaries for Manifold Bio roles on Migrate Mate range from about $70,000 to $275,000 per year across 8 open roles, as of July 16, 2026.
Open Roles at Manifold Bio
Showing 8 of 8+ Manifold Bio jobs
Position
Manifold Bio is seeking a scientist experienced in protein chemistry, oligonucleotide chemistry, and bioconjugation. You will be responsible for designing and executing bioconjugation strategies for protein-oligonucleotide conjugates, as well as bioconjugated fluorophores, tags, and peptides. In addition to performing, optimizing, and troubleshooting bioconjugation in the lab, you will oversee contract research organizations executing specialized or large-scale bioconjugation projects. You will consistently execute core bioconjugation protocols, proactively contribute to workflow optimization, and bring your excitement for rigorous science and troubleshooting to our growing cross-functional team. You will join a team with deep experience in protein chemistry, RNA biology, and biology, and work closely with a highly interdisciplinary team of creative experimental and computational scientists to advance our tissue-targeted oligomedicines pipeline.
Responsibilities
- Design, execute, and troubleshoot bioconjugation reactions for protein-oligonucleotide conjugates and other bioconjugated fluorophores, tags, and peptides
- Purify and characterize bioconjugated products using standard biochemical techniques
- Build and maintain a parallelized, efficient workflow to support in vivo target engagement evaluation of multiple new candidate tissue-targeting shuttles using tool siRNA payloads
- Oversee contract research organizations (CROs) performing specialized or large-scale bioconjugation projects
- Proactively identify and drive optimization of existing bioconjugation and analytical workflows
- Maintain accurate, detailed experimental records and contribute to scientific discussions and experimental design
Required Qualifications
- PhD in Biochemistry, Chemistry, Molecular Biology, or a related scientific field
- Minimum of 3+ years of hands-on wet-lab experience in protein production, purification, and biochemistry
- Proficiency in basic biochemical techniques (e.g., protein quantification, gel electrophoresis, chromatography)
- Proven ability to troubleshoot biochemical assays and optimize experimental protocols
- Experience with bioconjugation chemistry principles and methodologies (e.g., cysteine-based, lysine-based, and/or enzymatic conjugation strategies)
- Familiarity with oligonucleotide chemistry and handling
Preferred Qualifications
- Experience with high-throughput screening or automation
- Familiarity with analytical techniques for biomolecule characterization (e.g., mass spectrometry, DLS, BLI, SPR)
- Experience establishing and troubleshooting enzymatic assays
- Demonstrated leadership or mentorship of junior scientists
- Strong presentation skills and design sensibility
Why you might be a good fit
- You get energy from solving a critical-path bottleneck and building the workflow that unblocks the rest of the team
- You take rigor seriously and want your bioconjugated constructs to be reproducible at scale
- You're comfortable managing external partners and holding CRO-generated work to the same bar as your own
- You're scrappy, iterate quickly, and take ownership of projects through to resolution
- You communicate clearly, document rigorously, and enjoy working across a highly interdisciplinary team
If you’re excited to use unique protein technologies to shape an innovative drug development strategy, build meaningful industry partnerships, and contribute directly to our mission of advancing breakthrough treatments, please apply!
Base Salary Range: $118,000 - $138,000
This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.
This role is eligible for:
- Annual performance-based target bonus
- Stock options
- Comprehensive medical, dental, and vision coverage
- 401(k) plan
- Flexible paid time off and holidays
- Perks including on-site gym, onsite lunch, and commuter support
Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.
We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.
Position
Manifold Bio is seeking a scientist experienced in protein chemistry, oligonucleotide chemistry, and bioconjugation. You will be responsible for designing and executing bioconjugation strategies for protein-oligonucleotide conjugates, as well as bioconjugated fluorophores, tags, and peptides. In addition to performing, optimizing, and troubleshooting bioconjugation in the lab, you will oversee contract research organizations executing specialized or large-scale bioconjugation projects. You will consistently execute core bioconjugation protocols, proactively contribute to workflow optimization, and bring your excitement for rigorous science and troubleshooting to our growing cross-functional team. You will join a team with deep experience in protein chemistry, RNA biology, and biology, and work closely with a highly interdisciplinary team of creative experimental and computational scientists to advance our tissue-targeted oligomedicines pipeline.
Responsibilities
- Design, execute, and troubleshoot bioconjugation reactions for protein-oligonucleotide conjugates and other bioconjugated fluorophores, tags, and peptides
- Purify and characterize bioconjugated products using standard biochemical techniques
- Build and maintain a parallelized, efficient workflow to support in vivo target engagement evaluation of multiple new candidate tissue-targeting shuttles using tool siRNA payloads
- Oversee contract research organizations (CROs) performing specialized or large-scale bioconjugation projects
- Proactively identify and drive optimization of existing bioconjugation and analytical workflows
- Maintain accurate, detailed experimental records and contribute to scientific discussions and experimental design
Required Qualifications
- PhD in Biochemistry, Chemistry, Molecular Biology, or a related scientific field
- Minimum of 3+ years of hands-on wet-lab experience in protein production, purification, and biochemistry
- Proficiency in basic biochemical techniques (e.g., protein quantification, gel electrophoresis, chromatography)
- Proven ability to troubleshoot biochemical assays and optimize experimental protocols
- Experience with bioconjugation chemistry principles and methodologies (e.g., cysteine-based, lysine-based, and/or enzymatic conjugation strategies)
- Familiarity with oligonucleotide chemistry and handling
Preferred Qualifications
- Experience with high-throughput screening or automation
- Familiarity with analytical techniques for biomolecule characterization (e.g., mass spectrometry, DLS, BLI, SPR)
- Experience establishing and troubleshooting enzymatic assays
- Demonstrated leadership or mentorship of junior scientists
- Strong presentation skills and design sensibility
Why you might be a good fit
- You get energy from solving a critical-path bottleneck and building the workflow that unblocks the rest of the team
- You take rigor seriously and want your bioconjugated constructs to be reproducible at scale
- You're comfortable managing external partners and holding CRO-generated work to the same bar as your own
- You're scrappy, iterate quickly, and take ownership of projects through to resolution
- You communicate clearly, document rigorously, and enjoy working across a highly interdisciplinary team
If you’re excited to use unique protein technologies to shape an innovative drug development strategy, build meaningful industry partnerships, and contribute directly to our mission of advancing breakthrough treatments, please apply!
Base Salary Range: $118,000 - $138,000
This reflects the typical offer range for this role, based on experience, role scope, and internal equity. Final compensation decisions are made using a consistent leveling framework and consider the candidate’s experience, interview performance, and expected impact.
This role is eligible for:
- Annual performance-based target bonus
- Stock options
- Comprehensive medical, dental, and vision coverage
- 401(k) plan
- Flexible paid time off and holidays
- Perks including on-site gym, onsite lunch, and commuter support
Our compensation ranges are reviewed annually to ensure alignment with market trends and internal equity.
We value different experiences and ways of thinking and believe the most talented teams are built by bringing together people of diverse cultures, genders, and backgrounds.
Job Roles at Manifold Bio
Working at Manifold Bio
Manifold Bio's 8 open roles are across all levels, and about 0% are remote or hybrid. The most active teams are AI (Artificial Intelligence), business strategy, and data analytics. Manifold Bio is a biotechnology company that combines machine learning, protein engineering, and pharmacology research to advance drug development. The work spans computational and wet-lab science, with roles across AI and machine learning research, bioconjugation, assay development, in vitro and in vivo pharmacology, and product management. Most Manifold Bio roles are based in Boston.
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Browse jobs by roleManifold Bio Jobs: Frequently Asked Questions
How many jobs is Manifold Bio hiring for right now?
Manifold Bio is hiring for 8 open roles on Migrate Mate as of July 16, 2026, updated daily, concentrated in AI (Artificial Intelligence) and business strategy. Roles span both computational and laboratory science disciplines, ranging from AI and machine learning positions to wet-lab and pharmacology research roles. Migrate Mate pulls Manifold Bio's current postings so the count reflects what is actively open.
What kinds of roles does Manifold Bio hire for?
The most active teams are AI (Artificial Intelligence), business strategy, and data analytics. Manifold Bio hires across scientific research, computational biology, and technical product roles. Open positions include AI and machine learning scientists and engineers, computational scientists, bioconjugation researchers, in vitro and in vivo pharmacology associates, and product managers focused on AI platforms. Most postings are across all levels, covering both bench scientists and research engineers.
Are Manifold Bio jobs remote or in-person?
Mostly on-site. About 0% of Manifold Bio's open roles on Migrate Mate are remote or hybrid as of July 16, 2026, with the rest based in Boston. Each Manifold Bio listing shows its work location so you can filter before applying.
How do I apply to a job at Manifold Bio?
Find a Manifold Bio role on Migrate Mate, then follow the listing directly to Manifold Bio's own careers page to complete the application. Manifold Bio manages its own hiring process, including application review, interviews, and offers. Migrate Mate keeps the listings current so you can browse what is open and move straight to the source to apply.
What do Manifold Bio jobs pay?
Listed salaries for Manifold Bio roles on Migrate Mate range from about $70,000 to $275,000 per year as of July 16, 2026, with most postings at across all levels. Exact pay is set by Manifold Bio and shown on each listing.
Does Manifold Bio hire entry-level?
Most of Manifold Bio's open roles on Migrate Mate are across all levels as of July 16, 2026. Check individual Manifold Bio listings for stated experience requirements.
Where is Manifold Bio hiring?
Most Manifold Bio roles are based in Boston, and about 0% offer remote or hybrid work as of July 16, 2026. Migrate Mate shows the location on each listing.