Olema Oncology Jobs Hiring Now
Olema Oncology is hiring for 11 open roles on Migrate Mate as of July 16, 2026, concentrated in clinical trials and business strategy, with listed salaries up to about $340,000. Migrate Mate updates Olema Oncology's live openings daily. Olema Oncology is a clinical-stage biopharmaceutical company focused on developing therapies for women's cancers.
Find Olema Oncology JobsOverview
Olema Oncology hiring data on Migrate Mate, as of July 16, 2026.
- Open jobs
- 11
- Top team
- Clinical Trials
- Seniority
- Manager level or above
- Work type
- 0% remote or hybrid
- Top location
- San Francisco
- Salary range
- $100,000–$340,000
Listed salaries for Olema Oncology roles on Migrate Mate range from about $100,000 to $340,000 per year across 11 open roles, as of July 16, 2026.
Open Roles at Olema Oncology
Showing 11 of 11+ Olema Oncology jobs
Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It's an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon.
Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity.
Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC.
Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.
If you're ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what's beyond.
About the Role >>> Senior Clinical Trial Associate
As the Senior Clinical Trial Associate reporting to the Senior Manager, Clinical Trial Leader, you will provide comprehensive administrative and operational support to clinical team members across all study activities, including both in-house and outsourced trials. This role supports cross-functional study execution through coordination with internal teams, external vendors, and site staff, and may include contributing to study documentation such as informed consent forms (ICFs) and central IRB submissions, supporting site payments and other study-related operational activities, as well as liaising with and following up with investigator sites. Responsibilities include assisting with study start-up, maintenance, and closeout activities; managing study documentation and materials; supporting vendor management; and maintaining study trackers and financial records. This position adheres to Clinical Standard Operating Procedures and Good Clinical Practice (ICH) guidelines.
This role is based out of either our office San Francisco or Cambridge office and will require approximately 10% travel.
Your work will primarily encompass:
- Supports the Clinical Trial Lead (CTL) and Study Execution Team (SET), ensuring ongoing accurate and essential documentation of study conduct
- Manages study-related vendors and serves as a point of contact for contracted CROs, study staff, contract labs, and other study vendors
- Acts as a key point of contact for investigator sites, facilitating communication, and ensuring effective coordination of study-related activities
- Conducts oversight of sample collection, shipment, and analyses
- Conducts reconciliation and tracking of study processes in collaboration with study team and escalates issues in a timely fashion to study lead
- Identifies potential risks and proactively resolves issues with CROs
- Assists in the development of vendor management and other study plans and compiles study and quality metrics for CTL, management, and/or team review(s)
- Facilitates flow and maintenance of correspondence with vendors and sites to provide or obtain study-specific information
- Ensures receipt, completeness, accuracy, and appropriate filing (Trial Master File, study SharePoint, other study or Olema-specific systems) of clinical and administrative documents
- Assists in coordination of study initiation documentation materials, including support for central IRB submission documents and review of site-specific informed consent forms.
- Coordinates electronic distribution and/or shipment of study-related materials, as appropriate
- Collaborates with relevant team members in the coordination and tracking of vendor and investigator site contracts, budgets, invoices, and/or payments as needed
- Contributes to the development of the TMF plan and conducts periodic quality control reviews and records reconciliation of the Trial Master File (TMF)
- Performs study and departmental administrative and clerical duties such as preparing agendas and minutes for team meetings and providing meeting planning and presentations
- Actively participates in department initiatives and goals, providing suggestions that support the vision, mission, and enhancement of Clinical Operations; may lead certain SOPs or other processes
Ideal Candidate Profile >>>
A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.
Knowledge
- Bachelor's degree is required
- Familiarity with FDA/EMA regulatory requirements and ICH/GCP guidelines is preferred
- Working knowledge of clinical protocols
Experience
- Minimum of 3 years of related industry experience is required
- Senior CTA requires 2 years' experience working as a Clinical Trial Associate.
- Proficiency with Microsoft applications (e.g., Microsoft Word, Excel, PowerPoint, Outlook)
- Experience with leading small group meetings and/or managing vendor relationships
Attributes
- Highly motivated and enjoys working in a fast-paced, dynamic environment
- Excellent teamwork and collaboration skills
- Good organizational skills, ability to manage multiple tasks and meticulous attention to detail
- Excellent written and verbal communication skills
- Ability to accommodate a flexible work schedule according to clinical trial(s) priorities, as needed
The base pay range for this position is expected to be $110,000 - $120,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.
#LI-CK1
Important Information >>>
We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.
Please note: Olema doesn't accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.
Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema's official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview.
Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It's an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon.
Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity.
Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC.
Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.
If you're ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what's beyond.
About the Role >>> Senior Clinical Trial Associate
As the Senior Clinical Trial Associate reporting to the Senior Manager, Clinical Trial Leader, you will provide comprehensive administrative and operational support to clinical team members across all study activities, including both in-house and outsourced trials. This role supports cross-functional study execution through coordination with internal teams, external vendors, and site staff, and may include contributing to study documentation such as informed consent forms (ICFs) and central IRB submissions, supporting site payments and other study-related operational activities, as well as liaising with and following up with investigator sites. Responsibilities include assisting with study start-up, maintenance, and closeout activities; managing study documentation and materials; supporting vendor management; and maintaining study trackers and financial records. This position adheres to Clinical Standard Operating Procedures and Good Clinical Practice (ICH) guidelines.
This role is based out of either our office San Francisco or Cambridge office and will require approximately 10% travel.
Your work will primarily encompass:
- Supports the Clinical Trial Lead (CTL) and Study Execution Team (SET), ensuring ongoing accurate and essential documentation of study conduct
- Manages study-related vendors and serves as a point of contact for contracted CROs, study staff, contract labs, and other study vendors
- Acts as a key point of contact for investigator sites, facilitating communication, and ensuring effective coordination of study-related activities
- Conducts oversight of sample collection, shipment, and analyses
- Conducts reconciliation and tracking of study processes in collaboration with study team and escalates issues in a timely fashion to study lead
- Identifies potential risks and proactively resolves issues with CROs
- Assists in the development of vendor management and other study plans and compiles study and quality metrics for CTL, management, and/or team review(s)
- Facilitates flow and maintenance of correspondence with vendors and sites to provide or obtain study-specific information
- Ensures receipt, completeness, accuracy, and appropriate filing (Trial Master File, study SharePoint, other study or Olema-specific systems) of clinical and administrative documents
- Assists in coordination of study initiation documentation materials, including support for central IRB submission documents and review of site-specific informed consent forms.
- Coordinates electronic distribution and/or shipment of study-related materials, as appropriate
- Collaborates with relevant team members in the coordination and tracking of vendor and investigator site contracts, budgets, invoices, and/or payments as needed
- Contributes to the development of the TMF plan and conducts periodic quality control reviews and records reconciliation of the Trial Master File (TMF)
- Performs study and departmental administrative and clerical duties such as preparing agendas and minutes for team meetings and providing meeting planning and presentations
- Actively participates in department initiatives and goals, providing suggestions that support the vision, mission, and enhancement of Clinical Operations; may lead certain SOPs or other processes
Ideal Candidate Profile >>>
A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.
Knowledge
- Bachelor's degree is required
- Familiarity with FDA/EMA regulatory requirements and ICH/GCP guidelines is preferred
- Working knowledge of clinical protocols
Experience
- Minimum of 3 years of related industry experience is required
- Senior CTA requires 2 years' experience working as a Clinical Trial Associate.
- Proficiency with Microsoft applications (e.g., Microsoft Word, Excel, PowerPoint, Outlook)
- Experience with leading small group meetings and/or managing vendor relationships
Attributes
- Highly motivated and enjoys working in a fast-paced, dynamic environment
- Excellent teamwork and collaboration skills
- Good organizational skills, ability to manage multiple tasks and meticulous attention to detail
- Excellent written and verbal communication skills
- Ability to accommodate a flexible work schedule according to clinical trial(s) priorities, as needed
The base pay range for this position is expected to be $110,000 - $120,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.
#LI-CK1
Important Information >>>
We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.
We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.
Please note: Olema doesn't accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.
Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema's official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview.
Job Roles at Olema Oncology
Working at Olema Oncology
Olema Oncology's 11 open roles are manager level or above, and about 0% are remote or hybrid. The most active teams are clinical trials, business strategy, and AI (Artificial Intelligence). Olema Oncology is a clinical-stage biopharmaceutical company developing targeted treatments for cancers that disproportionately affect women. Open positions span quality assurance, clinical development, medical affairs, research science, and commercial functions. Most Olema Oncology roles are based in San Francisco and Boston.
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Browse jobs by roleOlema Oncology Jobs: Frequently Asked Questions
How many jobs is Olema Oncology hiring for right now?
Olema Oncology is hiring for 11 open roles on Migrate Mate as of July 16, 2026, updated daily, concentrated in clinical trials and business strategy. Positions range from scientific research and clinical development to quality assurance and commercial leadership. Migrate Mate pulls the latest Olema Oncology openings each day so the count reflects what is actively accepting applications.
What kinds of roles does Olema Oncology hire for?
The most active teams are clinical trials, business strategy, and AI (Artificial Intelligence). Olema Oncology recruits across quality assurance, clinical science, medical affairs, biology research, and senior commercial and marketing functions. Roles include scientists, clinical trial associates, medical science liaisons, and vice-president-level leaders. Most postings are manager level or above, reflecting the company's focus on experienced professionals in oncology drug development.
Are Olema Oncology jobs remote or in-person?
Mostly on-site. About 0% of Olema Oncology's open roles on Migrate Mate are remote or hybrid as of July 16, 2026, with the rest based in San Francisco. Each Olema Oncology listing shows its work location so you can filter before applying.
How do I apply to a job at Olema Oncology?
Find a Olema Oncology role on Migrate Mate, then follow the listing directly through to Olema Oncology's own careers page to submit your application. Olema Oncology manages its own hiring process, including application review, interviews, and offers. Migrate Mate does not collect applications on Olema Oncology's behalf.
What do Olema Oncology jobs pay?
Listed salaries for Olema Oncology roles on Migrate Mate range from about $100,000 to $340,000 per year as of July 16, 2026, with most postings at manager level or above. Exact pay is set by Olema Oncology and shown on each listing.
Does Olema Oncology hire entry-level?
Most of Olema Oncology's open roles on Migrate Mate are manager level or above as of July 16, 2026. Entry-level openings are limited. Check individual Olema Oncology listings for stated experience requirements.
Where is Olema Oncology hiring?
Most Olema Oncology roles are based in San Francisco and Boston, and about 0% offer remote or hybrid work as of July 16, 2026. Migrate Mate shows the location on each listing.