Prisma Health Jobs Hiring Now

Prisma Health is hiring for 1,254 open roles on Migrate Mate as of October 15, 2026, concentrated in healthcare administration and customer service. Migrate Mate updates Prisma Health's live openings daily. Prisma Health is a large nonprofit health system operating hospitals, medical practices, and specialty care facilities across South Carolina.

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Overview

Prisma Health hiring data on Migrate Mate, as of October 15, 2026.

Open jobs
1,254
Top team
Healthcare Administration
Seniority
Across all levels
Work type
1% remote or hybrid
Top location
Greenville

Open Roles at Prisma Health

Showing 25 of 1,254+ Prisma Health jobs

Prisma Health
Clinical Assistant-Ambulatory, Physical Therapy Maryville, FT, Days
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Prisma Health
Added 3w ago
Clinical Assistant-Ambulatory, Physical Therapy Maryville, FT, Days
Prisma Health
Maryville, Tennessee
Business Operations
Program Management
Project Management
Bachelor's degree
10,000+

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Prisma Health
Patient Support Technician, Facility Resource Pool, FT, Day
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Prisma Health
Added 3w ago
Patient Support Technician, Facility Resource Pool, FT, Day
Prisma Health
Columbia, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
High school diploma or GED
10,000+

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Prisma Health
Patient Services Representative, Carolina Internal Medicine, FT, Days
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Prisma Health
Added 3w ago
Patient Services Representative, Carolina Internal Medicine, FT, Days
Prisma Health
Greenville, South Carolina
Business Operations
Customer Service
Customer Support
Sales
High school diploma or GED
10,000+

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Prisma Health
Surgery Scheduler, Colorectal Surgery, FT, Days
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Prisma Health
Added 3w ago
Surgery Scheduler, Colorectal Surgery, FT, Days
Prisma Health
Maryville, Tennessee
Customer Service
Customer Support
Hospitality & Guest Services
High school diploma or GED
10,000+

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Prisma Health
Patient Support Technician, Facility Resource Pool, FT, Nights
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Prisma Health
Added 3w ago
Patient Support Technician, Facility Resource Pool, FT, Nights
Prisma Health
Columbia, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
High school diploma or GED
10,000+

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Prisma Health
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Days
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Days
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree in nursing
10,000+

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Prisma Health
Nursing Assistant Certified/Unit Secretary, Recovery Room, FT, Days
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Prisma Health
Added 3w ago
Nursing Assistant Certified/Unit Secretary, Recovery Room, FT, Days
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
10,000+

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Prisma Health
Registered Nurse (RN) - Ambulatory, Surgery Wound Care, PT, DaysFT
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Ambulatory, Surgery Wound Care, PT, DaysFT
Prisma Health
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree in nursing
10,000+

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Prisma Health
Supervisor, Facility Supply Chain Operations, FT, Days
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Prisma Health
Added 3w ago
Supervisor, Facility Supply Chain Operations, FT, Days
Prisma Health
Greenville, South Carolina
Business Operations
Customer Service
Customer Support
Sales
High school diploma or GED
10,000+

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Prisma Health
Assistant Nurse Manager ((RN), Medical ICU, FT, Variable
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Prisma Health
Added 3w ago
Assistant Nurse Manager ((RN), Medical ICU, FT, Variable
Prisma Health
Greer, South Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)
10,000+

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Prisma Health
Periop Technician, Operating Room, FT, Variable
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Prisma Health
Added 3w ago
Periop Technician, Operating Room, FT, Variable
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
High school diploma or GED
10,000+

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Prisma Health
Respiratory Therapist (PRN)
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Prisma Health
Added 3w ago
Respiratory Therapist (PRN)
Prisma Health
Greenville, South Carolina
Manufacturing Operations
Project Management
Quality Control
NRP Certification
10,000+

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Prisma Health
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Nights
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Nights
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree in nursing
10,000+

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Prisma Health
Anesthetist - Independent Contractor-Oconee
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Prisma Health
Added 3w ago
Anesthetist - Independent Contractor-Oconee
Prisma Health
Seneca, South Carolina
Business Operations
Compliance & Risk
Executive Leadership & C-Suite
Master's degree
10,000+

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Prisma Health
Manager, Facility Supply Chain Operations I
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Prisma Health
Added 3w ago
Manager, Facility Supply Chain Operations I
Prisma Health
Sumter, South Carolina
Logistics & Fleet Management
Procurement & Supply Chain
Supply Chain
Master's degree
10,000+

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Prisma Health
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Variable
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Acute Care, Facility Resource Pool, FT, Variable
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree in nursing
10,000+

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Prisma Health
Registered Nurse (RN) - Hospital Care Manager, Hospital Care Management, PT, Days
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Hospital Care Manager, Hospital Care Management, PT, Days
Prisma Health
Maryville, Tennessee
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Nursing Diploma
10,000+

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Prisma Health
Registered Nurse (RN) - Ambulatory, Surgery Wound Care, FT, Days
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Prisma Health
Added 3w ago
Registered Nurse (RN) - Ambulatory, Surgery Wound Care, FT, Days
Prisma Health
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
Bachelor's degree in nursing
10,000+

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Prisma Health
Certified Nursing Assistant (CNA), Medical/Surgical Unit, PRN, Days
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Prisma Health
Added 3w ago
Certified Nursing Assistant (CNA), Medical/Surgical Unit, PRN, Days
Prisma Health
Seneca, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
10,000+

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Prisma Health
Speech Pathologist, FT, Days
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Prisma Health
Added 3w ago
Speech Pathologist, FT, Days
Prisma Health
Maryville, Tennessee
Customer Service
Customer Support
Hospitality & Guest Services
Master's degree in speech-language pathology (SLP)
10,000+

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Prisma Health
Patient Services Representative-Blue Ridge Women's Center, FT, Days
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Prisma Health
Added 3w ago
Patient Services Representative-Blue Ridge Women's Center, FT, Days
Prisma Health
Seneca, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
High school diploma or GED
10,000+

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Prisma Health
Licensed Practical Nurse (LPN)-Acute Care, Behavioral Care, PT, Days
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Prisma Health
Added 3w ago
Licensed Practical Nurse (LPN)-Acute Care, Behavioral Care, PT, Days
Prisma Health
Columbia, South Carolina
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
10,000+

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Prisma Health
Registered Nurse (RN)-Acute Care, Emergency Dept, Full Time, Night
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Prisma Health
Added 3w ago
Registered Nurse (RN)-Acute Care, Emergency Dept, Full Time, Night
Prisma Health
Easley, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Nursing Diploma
10,000+

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Prisma Health
Registered Nurse (RN)-Acute Care, Med Surg, FT, Days
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Prisma Health
Added 3w ago
Registered Nurse (RN)-Acute Care, Med Surg, FT, Days
Prisma Health
Columbia, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Nursing Diploma
10,000+

Have you applied for this role?

Prisma Health
Registered Nurse (RN)-Acute Care, Behavioral Care, FT, Days
We won't show you this job again
Prisma Health
Added 3w ago
Registered Nurse (RN)-Acute Care, Behavioral Care, FT, Days
Prisma Health
Columbia, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Nursing Diploma
10,000+

Have you applied for this role?

Job Roles at Prisma Health

Healthcare Administration209 jobs
Customer Service122 jobs
Business Operations41 jobs
Business Development34 jobs
Clinical Support22 jobs
Program Management11 jobs
Manufacturing Operations9 jobs
Account Management6 jobs
Human Resources (HR) — Generalist5 jobs
Allied Health4 jobs

Working at Prisma Health

Prisma Health's 1,254 open roles are across all levels, and about 1% are remote or hybrid. The most active teams are healthcare administration, customer service, and business operations. Prisma Health is a nonprofit health system providing hospital-based acute care, outpatient clinical services, rehabilitative care, and specialty programs across South Carolina. Roles span registered nursing, nursing assistance, dietetics, occupational therapy, and clinical management, serving patients across inpatient, ambulatory, and intensive care settings. Most Prisma Health roles are based in Greenville, with some in Columbia and Maryville.

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Prisma Health Jobs: Frequently Asked Questions

How many jobs is Prisma Health hiring for right now?

Prisma Health is hiring for 1,254 open roles on Migrate Mate as of October 15, 2026, updated daily, concentrated in healthcare administration and customer service. Positions range from bedside nursing and nursing assistance to registered dietitians, occupational therapists, and clinical care managers, spanning full-time, part-time, and PRN schedules across day and night shifts.

What kinds of roles does Prisma Health hire for?

The most active teams are healthcare administration, customer service, and business operations. Prisma Health posts roles across registered nursing, nursing assistance, dietetics, occupational therapy, exercise instruction, and clinical management. Specialties in the current openings include NICU, cardiac telemetry, surgical specialty, ambulatory practice, and day treatment programs. Most postings are across all levels, covering both clinical bedside positions and supervisory clinical leadership roles.

Are Prisma Health jobs remote or in-person?

Mostly on-site. About 1% of Prisma Health's open roles on Migrate Mate are remote or hybrid as of October 15, 2026, with the rest based in Greenville. Each Prisma Health listing shows its work location so you can filter before applying.

How do I apply to a job at Prisma Health?

Find a Prisma Health role on Migrate Mate, then follow the listing directly to Prisma Health's own careers site to complete the application. Prisma Health manages its own hiring process, including screening, interviews, and offers. Migrate Mate keeps Prisma Health's listings current so job seekers can track new openings as they appear.

Does Prisma Health hire entry-level?

Most of Prisma Health's open roles on Migrate Mate are across all levels as of October 15, 2026. Check individual Prisma Health listings for stated experience requirements.

Where is Prisma Health hiring?

Most Prisma Health roles are based in Greenville, with some in Columbia and Maryville, and about 1% offer remote or hybrid work as of October 15, 2026. Migrate Mate shows the location on each listing.