Director Of Project Management Jobs in Colorado
Director Of Project Management jobs in Colorado are open across Denver, Aurora, and Boulder and other Colorado metros, with employers like Sage Hospitality, University of Colorado, and WSP in the U.S. hiring at every experience level. Find a role that fits below and apply directly.
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Showing 5 of 39+ Director Of Project Management jobs
JOB SUMMARY
Medpace is continuing to add experienced CTM Directors and Sr. Project Managers to join our Clinical Trial Management Group to office in Denver, CO. This position will be responsible for mentoring CTMs as well as overseeing projects and sponsor relationships. Our therapeutic areas of focus include Oncology, Cardiovascular/Metabolic, Infectious Disease, Neuroscience, and more. We offer a very competitive salary/bonus program, plus equity grants which have become very lucrative for our associates.
This position is a full-time office-based role in our Denver, CO office, with some work-from-home flexibility following tenure with the company.
Responsibilities
- Mentor Clinical Trial Managers, Project Coordinators, and other study team members in the Denver, CO office
- Manage and provide accountability for day-to-day operations of the project, as defined by the contract and according to ICH/GCP and all other applicable laws, rules, and regulations
- Serve as primary Sponsor contact for operational project-specific issues and study deliverables
- Maintain in depth knowledge of protocol, therapeutic area, and indication
- Provide cross-functional oversight of internal project team members and deliverables, which includes ensuring all necessary project-specific training is provided
- Review and provide input for study protocol, edit check specifications, data analysis plan, and final study report, when applicable
- Develop operational project plans
- Manage risk assessment and execution
- Manage study vendors where applicable
- Manage site quality and monitoring deliverables
- Work collaboratively with HR to support recruitment of new staff in Denver office
- Serve as an escalation point for Clinical Operations in the Denver office
- Implement and support Medpace corporate strategies in Denver office
- Organize a cross-functional leadership team to align and support all associates in the Denver office.
BASIC QUALIFICATIONS
- Bachelor’s degree in a health-related field; Advanced degree in a health-related field preferred
- Experience in Phases 1-4; Phases 2-3 preferred
- 5+ years as a project/clinical trial manager within a CRO
- Management of overall project timeline
- Bid defense experience
- Strong leadership skills
COMPENSATION
A target salary range of $175,000 - $250,000 with potential for bonus and equity awards. Your compensation will be based on your skills and experience. Medpace offers the following benefits for full-time positions: medical, dental, vision, 401(k), vacation policy, sick days, paid holidays, work from home flexibility, short-term disability, long-term disability, health savings and flexible savings accounts, life and AD&D insurance, pet insurance, and reimbursement for travel expenses (including food and gas allowance, rental cars, and hotel accommodations). Applications will be accepted on an ongoing basis. For more details, please discuss with your recruiter.
MEDPACE OVERVIEW
Medpace is a full-service clinical contract research organization (CRO). We provide Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through its scientific and disciplined approach. We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, employing more than 6,000 people across 40+ countries.
WHY MEDPACE?
People. Purpose. Passion. Make a Difference Tomorrow. Join Us Today.
The work we’ve done over the past 30+ years has positively impacted the lives of countless patients and families who face hundreds of diseases across all key therapeutic areas. The work we do today will improve the lives of people living with illness and disease in the future.
DENVER PERKS
Denver Office Overview
- Flexible work environment
- Competitive PTO packages, starting at 20+ days
- Competitive compensation and benefits package
- Company-sponsored employee appreciation events
- Employee health and wellness initiatives
- Community involvement with local nonprofit organizations
- Structured career paths with opportunities for professional growth
- Discounts on local sports games, fitness gyms and attractions
- Modern, ecofriendly campus with an on-site fitness center
- RTD Eco Pass
- Secure bike storage room
AWARDS
Named a Top Workplace in 2024 by The Cincinnati Enquirer
Recognized by Forbes as one of America's Most Successful Midsize Companies in 2021, 2022, 2023 and 2024
Continually recognized with CRO Leadership Awards from Life Science Leader magazine based on expertise, quality, capabilities, reliability, and compatibility
WHAT TO EXPECT NEXT
A Medpace team member will review your qualifications and, if interested, you will be contacted with details for next steps.
JOB SUMMARY
Medpace is continuing to add experienced CTM Directors and Sr. Project Managers to join our Clinical Trial Management Group to office in Denver, CO. This position will be responsible for mentoring CTMs as well as overseeing projects and sponsor relationships. Our therapeutic areas of focus include Oncology, Cardiovascular/Metabolic, Infectious Disease, Neuroscience, and more. We offer a very competitive salary/bonus program, plus equity grants which have become very lucrative for our associates.
This position is a full-time office-based role in our Denver, CO office, with some work-from-home flexibility following tenure with the company.
Responsibilities
- Mentor Clinical Trial Managers, Project Coordinators, and other study team members in the Denver, CO office
- Manage and provide accountability for day-to-day operations of the project, as defined by the contract and according to ICH/GCP and all other applicable laws, rules, and regulations
- Serve as primary Sponsor contact for operational project-specific issues and study deliverables
- Maintain in depth knowledge of protocol, therapeutic area, and indication
- Provide cross-functional oversight of internal project team members and deliverables, which includes ensuring all necessary project-specific training is provided
- Review and provide input for study protocol, edit check specifications, data analysis plan, and final study report, when applicable
- Develop operational project plans
- Manage risk assessment and execution
- Manage study vendors where applicable
- Manage site quality and monitoring deliverables
- Work collaboratively with HR to support recruitment of new staff in Denver office
- Serve as an escalation point for Clinical Operations in the Denver office
- Implement and support Medpace corporate strategies in Denver office
- Organize a cross-functional leadership team to align and support all associates in the Denver office.
BASIC QUALIFICATIONS
- Bachelor’s degree in a health-related field; Advanced degree in a health-related field preferred
- Experience in Phases 1-4; Phases 2-3 preferred
- 5+ years as a project/clinical trial manager within a CRO
- Management of overall project timeline
- Bid defense experience
- Strong leadership skills
COMPENSATION
A target salary range of $175,000 - $250,000 with potential for bonus and equity awards. Your compensation will be based on your skills and experience. Medpace offers the following benefits for full-time positions: medical, dental, vision, 401(k), vacation policy, sick days, paid holidays, work from home flexibility, short-term disability, long-term disability, health savings and flexible savings accounts, life and AD&D insurance, pet insurance, and reimbursement for travel expenses (including food and gas allowance, rental cars, and hotel accommodations). Applications will be accepted on an ongoing basis. For more details, please discuss with your recruiter.
MEDPACE OVERVIEW
Medpace is a full-service clinical contract research organization (CRO). We provide Phase I-IV clinical development services to the biotechnology, pharmaceutical and medical device industries. Our mission is to accelerate the global development of safe and effective medical therapeutics through its scientific and disciplined approach. We leverage local regulatory and therapeutic expertise across all major areas including oncology, cardiology, metabolic disease, endocrinology, central nervous system, anti-viral and anti-infective. Headquartered in Cincinnati, Ohio, employing more than 6,000 people across 40+ countries.
WHY MEDPACE?
People. Purpose. Passion. Make a Difference Tomorrow. Join Us Today.
The work we’ve done over the past 30+ years has positively impacted the lives of countless patients and families who face hundreds of diseases across all key therapeutic areas. The work we do today will improve the lives of people living with illness and disease in the future.
DENVER PERKS
Denver Office Overview
- Flexible work environment
- Competitive PTO packages, starting at 20+ days
- Competitive compensation and benefits package
- Company-sponsored employee appreciation events
- Employee health and wellness initiatives
- Community involvement with local nonprofit organizations
- Structured career paths with opportunities for professional growth
- Discounts on local sports games, fitness gyms and attractions
- Modern, ecofriendly campus with an on-site fitness center
- RTD Eco Pass
- Secure bike storage room
AWARDS
Named a Top Workplace in 2024 by The Cincinnati Enquirer
Recognized by Forbes as one of America's Most Successful Midsize Companies in 2021, 2022, 2023 and 2024
Continually recognized with CRO Leadership Awards from Life Science Leader magazine based on expertise, quality, capabilities, reliability, and compatibility
WHAT TO EXPECT NEXT
A Medpace team member will review your qualifications and, if interested, you will be contacted with details for next steps.
See All 39 Director Of Project Management Jobs in Colorado
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Find JobsDirector Of Project Management Jobs by City in Colorado
Where Colorado roles are concentrated, by current openings.
Director Of Project Management Job Market in Colorado
A snapshot from current Colorado openings, updated as new roles post.
Who's Hiring
- Sage Hospitality6
- University of Colorado4
- WSP in the U.S.4
- LawnStarter3
- Medpace2
Top Industries Hiring
- Technology & Software8
- Education7
- Consulting & Professional Services6
- Construction & Real Estate4
- Electronics & Hardware3
What Colorado Employers Look For
The qualifications that appear most often in director of project management jobs across Colorado.
- 8 or more years of progressive project and program management experience
- PMP certification or equivalent credential such as PgMP or PMI-ACP
- Demonstrated experience managing enterprise-level programs with cross-functional teams
- Proficiency with project management tools such as Smartsheet, Microsoft Project, or Jira
- Bachelor's degree in business, engineering, or a related field
- Experience building or leading a PMO and establishing governance frameworks
Director Of Project Management Jobs in Colorado: Frequently Asked Questions
How many director of project management jobs are there in Colorado?
There are 39+ director of project management openings in Colorado on Migrate Mate as of June 2026, with the most roles in Denver, Aurora, and Boulder. New positions post regularly as employers across Colorado hire.
How much do director of project managements make in Colorado?
Director of project managements in Colorado earn a median of about $110,050 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $68,990 for the lowest 10% to over $171,630 for the top 10%. Pay rises with experience, specialty, and employer.
Which Colorado cities have the most director of project management jobs?
Denver, Aurora, and Boulder have the most director of project management openings in Colorado right now, with additional roles spread across smaller metros statewide.
Which companies hire director of project managements in Colorado?
Employers hiring director of project managements in Colorado include Sage Hospitality, University of Colorado, and WSP in the U.S., based on current listings on Migrate Mate as of June 2026.
Are there remote director of project management jobs in Colorado?
Yes. About 28% of director of project management openings tied to Colorado are remote or hybrid as of June 2026. The rest are on-site roles based in Colorado metros.
How do I apply for director of project management jobs in Colorado?
You can apply to director of project management jobs in Colorado directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Colorado location, then apply to each one that fits.
See All 39 Director Of Project Management Jobs in Colorado
Find roles in Colorado that match your experience and apply in just a few clicks.
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