Director Operational Excellence Jobs in Maryland
Director Operational Excellence jobs in Maryland are open across Baltimore, Bethesda, and College Park and other Maryland metros, with employers like Johns Hopkins University, University of Maryland Medical System, and Balfour Beatty hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
The Senior Director of Operational Technology (OT) is a pivotal leadership role that requires a proven professional with both strategic acumen and deep technical expertise to drive transformative initiatives across the Business Unit's (BU) operational technology landscape.
This role requires a senior leader to define and execute an OT strategy aligned with BU and platform priorities, leveraging emerging technologies—including AI—to drive efficiency and innovation. The Senior Director will oversee complex OT programs end‑to‑end while leading and developing the Bioscience OT team. Strong financial acumen is essential, including ownership of technology budgets, cost analysis, and ROI evaluation for major initiatives.
Success in this role depends on strong cross‑functional collaboration with IT, Operations, and Global Centers of Excellence to deliver fit‑for‑purpose solutions that achieve operational excellence. The ability to operate effectively within a matrix environment—aligning diverse stakeholders through clear communication, negotiation, and strategic focus—is critical to ensuring holistic, enterprise‑aligned transformation outcomes.
KEY RESPONSIBILITIES
- Develop and execute the OT strategic roadmap aligned to BU vision, enterprise goals, and regulatory requirements.
- Provide thought leadership on OT best practices, emerging technologies, and AI adoption to drive efficiency and business outcomes.
- Define and implement a robust OT governance framework, including policies, standards, risk management, and compliance for biotech operations.
- Lead and oversee complex OT transformation programs, ensuring strong program governance, stakeholder engagement, and on‑time delivery.
- Drive process improvement, technology implementation, and organizational change across site, BU, and global initiatives.
- Manage technology budgets, resources, and performance metrics, including forecasting, ROI evaluation, and prioritization of high‑impact initiatives.
- Lead, mentor, and develop a high‑performing IT/OT organization, acting as a trusted advisor to senior leadership.
KEY REQUIREMENTS
- 15+ years of experience in FDA‑regulated, GMP environments, preferably within Pharma/Biopharma manufacturing.
- Bachelor’s degree in IT/OT or related field, with strong preference for Biopharma IT focus.
- Deep technical expertise in OT systems, manufacturing technologies, and emerging OT trends.
- Proven leader of large‑scale digital and OT transformation initiatives in regulated environments.
- Strong understanding of manufacturing processes and the technologies that enable them.
- Exceptional communication skills with the ability to translate complex technical concepts into business outcomes and influence senior stakeholders.
- Visionary people leader with a strong track record of building, developing, and inspiring high‑performing OT teams, including practical experience leveraging AI.
Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.
Lonza is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a qualified individual with disability, protected veteran status, or any other characteristic protected by law.
See All 40 Director Operational Excellence Jobs in Maryland
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Find JobsDirector Operational Excellence Jobs by City in Maryland
Where Maryland roles are concentrated, by current openings.
Director Operational Excellence Job Market in Maryland
A snapshot from current Maryland openings, updated as new roles post.
Who's Hiring
- Johns Hopkins University4

- University of Maryland Medical System3

- Balfour Beatty2

- University of Maryland2

- Aligned Data Centers1

Top Industries Hiring
- Education12
- Healthcare & Medical Services6
- Manufacturing4
- Technology & Software4
- Construction & Real Estate3
What Maryland Employers Look For
The qualifications that appear most often in director operational excellence jobs across Maryland.
- Lean Six Sigma Black Belt or Master Black Belt certification required by most employers
- 7 to 10 years of progressive experience leading continuous improvement programs across business units
- Proven ability to design and deploy operating management systems at enterprise scale
- Proficiency with process mapping tools such as Visio, Minitab, or equivalent analytics platforms
- Experience facilitating value stream mapping and kaizen events with cross-functional teams
- Bachelor's degree in engineering, operations management, or a related technical discipline required
Director Operational Excellence Jobs in Maryland: Frequently Asked Questions
How many director operational excellence jobs are there in Maryland?
There are 40+ director operational excellence openings in Maryland on Migrate Mate as of June 2026, with the most roles in Baltimore, Bethesda, and College Park. New positions post regularly as employers across Maryland hire.
How much do director operational excellences make in Maryland?
Director operational excellences in Maryland earn a median of about $117,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $58,190 for the lowest 10% to over $235,850 for the top 10%. Pay rises with experience, specialty, and employer.
Which Maryland cities have the most director operational excellence jobs?
Baltimore, Bethesda, and College Park have the most director operational excellence openings in Maryland right now, with additional roles spread across smaller metros statewide.
Which companies hire director operational excellences in Maryland?
Employers hiring director operational excellences in Maryland include Johns Hopkins University, University of Maryland Medical System, and Balfour Beatty, based on current listings on Migrate Mate as of June 2026.
Are there remote director operational excellence jobs in Maryland?
Yes. About 13% of director operational excellence openings tied to Maryland are remote or hybrid as of June 2026. The rest are on-site roles based in Maryland metros.
How do I apply for director operational excellence jobs in Maryland?
You can apply to director operational excellence jobs in Maryland directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Maryland location, then apply to each one that fits.
See All 40 Director Operational Excellence Jobs in Maryland
Find roles in Maryland that match your experience and apply in just a few clicks.
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