Senior Systems Administrator Jobs in Irvine, CA
Senior Systems Administrator jobs in Irvine, California are open across the metro, with employers like Ingram Micro, Wipfli, and Diality hiring at every experience level. Scan the live roles below and apply to whichever ones fit.
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Company & Job Overview
Diality is a medical device company focused on developing solutions to improve lives impacted by kidney disease. Diality offers the Moda-flx Hemodialysis System, a user-friendly, mobile, and connected hemodialysis system designed to maximize clinical flexibility and ease-of-use for both clinical and non-clinical users. The Moda-flx Hemodialysis system combines flow rate capabilities of conventional in-center dialysis devices with a fully integrated reverse osmosis (RO) water filtration system to provide a broad range of prescriptions and meet the needs of any professional dialysis care setting.
The IT Systems Administrator is responsible for maintaining and securing Diality’s IT infrastructure, including servers, cloud services, and enterprise applications. This role works closely with the IT Director and MSP to ensure system reliability and compliance.
Responsibilities
- Administer servers, cloud services, and identity platforms
- Manage backups, patching, and system monitoring
- Support cybersecurity tools including EDR, vulnerability management, and logging
- Support integrations and system upgrades
- Manage Microsoft 365 services including Exchange Online, SharePoint, Teams, OneDrive, Intune, and Azure AD.
- Conduct server patching, OS hardening, and lifecycle management.
- Configure and support switches, firewalls, Wi-Fi, VPNs, and site-to-site networking.
- Troubleshoot network performance, segmentation, routing, and connectivity issues.
- Support IP assignments, cabling, rack management, and vendor coordination
- Monitor and respond to security events, alerts, and vulnerabilities.
Required Skills & Abilities
- Strong knowledge of Windows Server, Azure AD, Microsoft 365
- Experience with backup, patching, and monitoring tools
- Understanding of compliance frameworks (FDA, ISO, NIST)
- Strong troubleshooting and documentation skills
- Strong AWS and Azure cloud experience
Education & Experience
- 5–8 years of systems administration experience
- Bachelor’s degree in IT, Computer Science, or equivalent experience
Travel
- 5% travel Domestically or Internationally
Physical Requirements
- Primarily office-based with up to 5% domestic/international travel.
The information contained in this job description is for compliance with the Americans with Disabilities Act (ADA) and is not an exhaustive list of duties performed for this position.
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Find JobsSenior Systems Administrator Job Market in Irvine
Who's Hiring
- Ingram Micro2

- Wipfli1

- Diality1D
- Taxrise1

- FluxErgy1

Top Industries Hiring
- Technology & Software5
- Medical Devices1
- Transportation & Logistics1
- Banking & Financial Services1
Senior Systems Administrator Jobs in Irvine: Frequently Asked Questions
How many senior systems administrator jobs are there in Irvine?
There are 18+ senior systems administrator openings in Irvine, California on Migrate Mate as of June 2026. New positions post regularly as Irvine employers hire.
Which companies hire senior systems administrators in Irvine?
Employers hiring senior systems administrators in Irvine include Ingram Micro, Wipfli, and Diality, based on current listings on Migrate Mate as of June 2026.
Are there remote senior systems administrator jobs in Irvine?
Yes. About 0% of senior systems administrator openings tied to Irvine are remote or hybrid as of June 2026. The rest are on-site roles based in and around Irvine.
Which industries hire the most senior systems administrators in Irvine?
The sectors hiring the most senior systems administrators in Irvine are Technology & Software, Medical Devices, and Transportation & Logistics, based on current listings on Migrate Mate as of June 2026.
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