Senior Level Staff Applied Scientist Jobs

Senior level staff applied scientist jobs place experienced researchers in charge of modeling strategy, cross-functional project ownership, and the technical direction of applied science teams. Roles are concentrated across Technology & Software, Retail, and E-Commerce & Online Marketplaces, with a mix of on-site, remote, and hybrid settings, and employers like Amazon, SentiLink, and Apple hiring at this level now.

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Overview

Open roles40
Top stateCalifornia
Top employerAmazon
Top citySan Francisco, CA
Work type48% On-site
Top industryTechnology

Showing 5 of 40+ Senior Level Staff Applied Scientist jobs

Applied AI Scientist
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Added 2d ago
Applied AI Scientist
Apple
Seattle, Washington
Software Engineering
Data Science & Analytics
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
Data Analytics
$205k - $309k/yr
On-Site
Master's
10,000+

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Senior Applied Scientist
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Added 3d ago
Senior Applied Scientist
Amazon.com
New York, New York
Data Science & Analytics
Software Engineering
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
$167k - $260k/yr
On-Site
Doctorate
10,000+

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Sr. Applied Scientist, APM Video Science
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Added 3d ago
Sr. Applied Scientist, APM Video Science
Amazon.com
New York, New York
Clinical Trials
Laboratory Research
Research & Academia
$184k - $249k/yr
Master's degree
10,000+

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Research Scientist, Applied Machine Learning Security (Agent Systems), SEAR
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Added 1w ago
Research Scientist, Applied Machine Learning Security (Agent Systems), SEAR
Apple
Cupertino, California
Biotech & Life Sciences
Laboratory Research
Research & Academia
$185k - $278k/yr
10,000+

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Principal Applied Scientist
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Added 2w ago
Principal Applied Scientist
Amazon.com
Boston, Massachusetts
Software Engineering
Data Science & Analytics
Data Engineering
Technical Product & Program Management
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
Technical Program Management
$199k - $269k/yr
On-Site
Doctorate
10,000+

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Senior Level Staff Applied Scientist Job Market

Who's Hiring

  • Amazon19
  • SentiLink6
  • Apple2
  • Figma2
  • Demandbase2

Top Industries Hiring

  • Technology & Software24
  • Retail11
  • E-Commerce & Online Marketplaces10
  • Electronics & Hardware2
  • Fintech1

Senior Level Staff Applied Scientist Jobs: Frequently Asked Questions

How do I get a senior level staff applied scientist job?

Employers at this level look for candidates who have owned end-to-end applied science projects, not just contributed to them. A strong record of translating research into production systems, evidence of cross-functional influence, and experience mentoring junior scientists all signal readiness. Presenting a portfolio of business-impact outcomes, rather than academic output alone, gives candidates a clear edge during the hiring process.

Which companies hire senior level staff applied scientists?

Companies hiring senior level staff applied scientists right now include Amazon, SentiLink, and Apple, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to come from technology companies, healthcare and life sciences organizations, and large enterprises investing in AI and machine learning capabilities.

Are there remote senior level staff applied scientist jobs?

Yes, though availability varies by employer and specialty. About 52% of senior level staff applied scientist openings are remote or hybrid as of November 2026, reflecting sustained demand for experienced scientists who can operate independently. On-site roles remain common in sectors where access to proprietary data infrastructure or lab environments is a core part of the work.

What makes a staff applied scientist role senior level?

Senior level staff applied scientist roles are defined by scope and ownership rather than task execution. At this stage, the expectation shifts to setting technical direction for a problem area, driving decisions that affect product or business outcomes, and mentoring other scientists on the team. These roles require the ability to operate with limited guidance and to represent applied science priorities in leadership conversations.

Which industries hire the most senior level staff applied scientists?

Senior Level staff applied scientist roles concentrate in Technology & Software, Retail, and E-Commerce & Online Marketplaces, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they have mature data ecosystems, complex modeling problems, and the organizational scale to support dedicated applied science functions.