TN Visa Bioinformatics Jobs
Bioinformatics roles qualify for TN visa sponsorship under the USMCA as Computer Systems Analyst positions, giving Canadian and Mexican professionals a cap-free path to U.S. employers building genomics pipelines, clinical data platforms, and computational biology teams. No lottery, no annual wait.
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Job Title: Bioinformatics Scientist
Requisition Number: RE54180
Department Name: 40100:VP of Research
Work Location: Lexington, KY
Grade Level: 49
Salary Range: $72,405-119,496/year
Type of Position: Staff
Position Time Status: Full-Time
Required Education: PhD
Required Related Experience: 3 yrs
Required License/Registration/Certification: None
Physical Requirements: Sitting for long periods of time
Shift: Monday – Friday; 8:00 am-5:00 pm; and occasional nights & weekends as needed.
Job Summary
The Bioinformatics Scientist — Computational Biology & Sequencing Sciences is a full-time staff position housed within the Cellular Genomics and Imaging (CGI) Core under the oversight of the Office of the Vice President for Research (VPR). The position provides expert bioinformatics support for UK’s research community engaged in analyzing data generated by next-generation sequencing (NGS) platforms such as, but not limited to, 10x Genomics Chromium X and the planned Xenium spatial analysis system.
The scientist in this position will develop and maintain reproducible bioinformatics pipelines and consult with investigators throughout the research lifecycle thereby contributing to the strategic growth of cutting edge research at UK. The position collaborates with UK Research Computing as a scientific user and partner — leveraging its infrastructure for research data processing and storage.
Skills / Knowledge / Abilities
- Demonstrated proficiency in R/Bioconductor and Python for biological data analysis
- Fluency with Linux/bash scripting
- Experience with version control (Git/GitHub)
- Hands-on experience building and deploying reproducible bioinformatics pipelines using Snakemake, Nextflow, or an equivalent workflow management framework in Linux-based HPC environments
- Experience with at least three major NGS data types: bulk and single cell RNA-seq, WGS/WES, bulk and single cell ATAC-seq, ChIP-seq, amplicon (16S/ITS), or single-cell/spatial transcriptomics
- Demonstrated ability to communicate complex computational methods clearly to biologists, clinicians, and non-computational investigators
- Experience writing bioinformatics methods sections for manuscripts or grant applications
- Ability to manage multiple concurrent projects, maintain accurate records, and meet deliverable timelines across a diverse investigator user base
Does this position have supervisory responsibilities? No
Preferred Education/Experience
- Experience with spatial transcriptomics platforms (10x Genomics Chromium, Visium, Xenium; Parse Biosciences; Slide-seq; or equivalent) — directly relevant to the CGI Core instrument portfolio
- Prior experience designing and administering researcher needs assessments, service satisfaction surveys, or outreach programs in a core facility or shared resource context
- Demonstrated experience developing and implementing cost-recovery pricing structures for bioinformatics services
- Familiarity with NIH Genomic Data Sharing Policy, dbGaP submission, HIPAA-compliant handling of human genomics data, and relevant IRB considerations
- Track record of co-authored peer-reviewed publications arising from collaborative computational biology projects
- Experience with long-read sequencing data analysis (Oxford Nanopore, PacBio) or multi-omics integration methods
- Experience with cloud computing platforms (AWS, Google Cloud, or Microsoft Azure) for scalable genomic analysis
- Contributions to open-source bioinformatics tools, community pipelines, or training curricula (e.g., Bioconductor, Galaxy, Carpentries)
Deadline to Apply: 05/01/2026
We value the well-being of each of our employees and are dedicated to creating a healthy place for everyone to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors, the University of Kentucky is a Tobacco & Drug Free campus.
The University follows both the federal and state Constitutions as well as all applicable federal and state laws on nondiscrimination. The University provides equal opportunities for qualified persons in all aspects of institutional operations and does not discriminate on the basis of race, color, national origin, ethnic origin, religion, creed, age, physical or mental disability, veteran status, uniformed service, political belief, sex, sexual orientation, gender identity, gender expression, pregnancy, marital status, genetic information or social or economic status.
Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.

Job Title: Bioinformatics Scientist
Requisition Number: RE54180
Department Name: 40100:VP of Research
Work Location: Lexington, KY
Grade Level: 49
Salary Range: $72,405-119,496/year
Type of Position: Staff
Position Time Status: Full-Time
Required Education: PhD
Required Related Experience: 3 yrs
Required License/Registration/Certification: None
Physical Requirements: Sitting for long periods of time
Shift: Monday – Friday; 8:00 am-5:00 pm; and occasional nights & weekends as needed.
Job Summary
The Bioinformatics Scientist — Computational Biology & Sequencing Sciences is a full-time staff position housed within the Cellular Genomics and Imaging (CGI) Core under the oversight of the Office of the Vice President for Research (VPR). The position provides expert bioinformatics support for UK’s research community engaged in analyzing data generated by next-generation sequencing (NGS) platforms such as, but not limited to, 10x Genomics Chromium X and the planned Xenium spatial analysis system.
The scientist in this position will develop and maintain reproducible bioinformatics pipelines and consult with investigators throughout the research lifecycle thereby contributing to the strategic growth of cutting edge research at UK. The position collaborates with UK Research Computing as a scientific user and partner — leveraging its infrastructure for research data processing and storage.
Skills / Knowledge / Abilities
- Demonstrated proficiency in R/Bioconductor and Python for biological data analysis
- Fluency with Linux/bash scripting
- Experience with version control (Git/GitHub)
- Hands-on experience building and deploying reproducible bioinformatics pipelines using Snakemake, Nextflow, or an equivalent workflow management framework in Linux-based HPC environments
- Experience with at least three major NGS data types: bulk and single cell RNA-seq, WGS/WES, bulk and single cell ATAC-seq, ChIP-seq, amplicon (16S/ITS), or single-cell/spatial transcriptomics
- Demonstrated ability to communicate complex computational methods clearly to biologists, clinicians, and non-computational investigators
- Experience writing bioinformatics methods sections for manuscripts or grant applications
- Ability to manage multiple concurrent projects, maintain accurate records, and meet deliverable timelines across a diverse investigator user base
Does this position have supervisory responsibilities? No
Preferred Education/Experience
- Experience with spatial transcriptomics platforms (10x Genomics Chromium, Visium, Xenium; Parse Biosciences; Slide-seq; or equivalent) — directly relevant to the CGI Core instrument portfolio
- Prior experience designing and administering researcher needs assessments, service satisfaction surveys, or outreach programs in a core facility or shared resource context
- Demonstrated experience developing and implementing cost-recovery pricing structures for bioinformatics services
- Familiarity with NIH Genomic Data Sharing Policy, dbGaP submission, HIPAA-compliant handling of human genomics data, and relevant IRB considerations
- Track record of co-authored peer-reviewed publications arising from collaborative computational biology projects
- Experience with long-read sequencing data analysis (Oxford Nanopore, PacBio) or multi-omics integration methods
- Experience with cloud computing platforms (AWS, Google Cloud, or Microsoft Azure) for scalable genomic analysis
- Contributions to open-source bioinformatics tools, community pipelines, or training curricula (e.g., Bioconductor, Galaxy, Carpentries)
Deadline to Apply: 05/01/2026
We value the well-being of each of our employees and are dedicated to creating a healthy place for everyone to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors, the University of Kentucky is a Tobacco & Drug Free campus.
The University follows both the federal and state Constitutions as well as all applicable federal and state laws on nondiscrimination. The University provides equal opportunities for qualified persons in all aspects of institutional operations and does not discriminate on the basis of race, color, national origin, ethnic origin, religion, creed, age, physical or mental disability, veteran status, uniformed service, political belief, sex, sexual orientation, gender identity, gender expression, pregnancy, marital status, genetic information or social or economic status.
Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.
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Get Access To All JobsTips for Finding TN Visa Sponsorship as a Bioinformatics
Map your degree to the right TN category
Bioinformatics sits under Computer Systems Analyst on the TN occupation list. Your degree in bioinformatics, computational biology, or computer science supports this classification. A life sciences degree alone may draw officer scrutiny at the port of entry.
Build a documentation package before applying
Assemble your CV, official transcripts, and a detailed employer support letter describing your duties in computational terms before you approach any employer. Gaps in this package cause delays at the border, not after.
Target employers with active computational biology teams
Pharma, biotech, and genomics companies with dedicated bioinformatics pipelines process TN sponsorship faster because their legal teams already understand the occupation. Filter your search to employers in those sectors rather than general tech companies unfamiliar with the classification.
Ask employers to confirm TN filing experience upfront
Request during early interviews whether the company has filed TN petitions before. Employers who have done this for Computer Systems Analyst roles can issue a compliant support letter quickly. Those without experience may delay your start date by weeks.
Use Migrate Mate to find TN-eligible bioinformatics roles
Search Migrate Mate to filter bioinformatics openings by employers with recent visa filings. This cuts the time you spend cold-applying to companies that lack experience with visa sponsorship.
Canadians can file at the port of entry without advance petition
If you hold Canadian citizenship, you present your support letter and credentials directly at a land border or airport preclearance. Mexican nationals must apply at a U.S. consulate in Mexico and should book appointments well before their target start date.
Bioinformatics jobs are hiring across the US. Find yours.
Find Bioinformatics JobsBioinformatics TN Visa: Frequently Asked Questions
Does bioinformatics qualify for the TN visa?
Yes. Bioinformatics professionals qualify under the Computer Systems Analyst category on the TN occupation list. Your role must involve designing or analyzing computational systems for biological data. A degree in bioinformatics, computational biology, or computer science supports this classification best. A life sciences degree without a computational focus may require a stronger support letter from your employer to satisfy a border officer.
How does the TN visa compare to H-1B for bioinformatics roles?
The TN visa has no annual cap and no lottery, so Canadian professionals can secure authorization at the port of entry on their start date. H-1B requires entering a lottery with roughly a one-in-three selection rate, and successful petitioners wait months before they can work. For bioinformatics, TN is faster and more predictable, though it does not allow dual intent and does not lead directly to a green card the way H-1B status can.
What documents does my employer need to provide for TN sponsorship?
Your employer must write a support letter on company letterhead that specifies your job title, describes your duties in terms that map to Computer Systems Analyst work, states your qualifications, confirms your compensation, and lists the employment period. The letter is not filed with any government agency in advance for Canadian applicants. Mexican nationals submit it as part of their consular application package. A vague or generic letter is one of the most common reasons officers ask additional questions.
Can I use Migrate Mate to find bioinformatics jobs that sponsor TN visas?
Yes. Migrate Mate is built specifically for Canadian and Mexican professionals seeking U.S. roles with TN visa sponsorship. You can search bioinformatics openings filtered by employers who have active TN sponsorship programs, which removes the guesswork of approaching companies that may not support the visa category. Starting your search there saves time compared to applying broadly and raising sponsorship later in the process.
What happens if my bioinformatics job duties change after I receive TN status?
If your role expands into responsibilities that no longer fit the Computer Systems Analyst description on your original support letter, you should obtain an amended letter reflecting the updated duties. Substantial changes to your position, such as moving into a purely managerial role with no systems analysis function, could affect TN eligibility at your next renewal. Keeping your job description current with what you actually do protects you at the border.
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