Senior Level Applied Science Manager Jobs
Senior level applied science manager jobs put experienced scientists and technical leaders in charge of research direction, model development roadmaps, and the cross-functional teams that deliver results at scale. Openings concentrate in Retail, Education, and Technology & Software, with a mix of on-site, remote, and hybrid settings, and employers like Amazon, lululemon, and Embry-Riddle Aeronautical University hiring at this level now.
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Twitch is looking for an Applied Scientist to lead computer vision and video manipulation work within Amazon Publisher Monetization (APM). You will apply large language models (LLMs), vision-language models (VLMs), and traditional computer vision techniques to build products that directly improve how millions of Twitch creators produce content and how viewers engage with it. This is a high-visibility project backed by senior leadership, and you will have the autonomy to evaluate both first-party and third-party solutions to deliver the highest quality results quickly. If you thrive in a fast-paced, startup-like environment where your scientific decisions shape the product roadmap, we want to hear from you.
Key job responsibilities
Design and deploy computer vision and video manipulation models using LLMs, VLMs, and traditional techniques, taking solutions from research prototype to production.
Partner with senior Product and Twitch leadership to translate customer needs into well-defined scientific problems and deliver end-to-end solutions.
Evaluate and integrate generative AI capabilities across Amazon Bedrock and third-party platforms, selecting the approach that maximizes product quality.
Drive the team's scientific agenda by proposing new initiatives, authoring technical documents, and contributing to external publications.
Mentor fellow scientists and engineers through code reviews, design guidance, and technical assessments that raise the overall quality bar.
A day in the life
You will split your time roughly evenly between independent research and collaborative sessions. Mornings often start with focused solo work — benchmarking a new VLM, writing model code, or analyzing experiment results. Midday you join working sessions with Product and Twitch leadership to align on requirements or review progress. Afternoons shift between pairing with engineers on production integration and mentoring teammates on evaluation methodology. Weekly science reviews and bi-weekly roadmap syncs keep the team aligned without over-scheduling your calendar.
About the team
The APM science team supports all of Amazon's Publisher Monetization efforts, building the models and systems behind Twitch's creator tools and ad experiences. The team includes applied scientists, software engineers, and product managers who collaborate daily to move ideas from whiteboard to production. We operate with a startup mentality — moving fast, wearing multiple hats, and iterating closely with Twitch and Product partners. We are accelerating investment in computer vision and generative AI, and this role will be central to that expansion.
BASIC QUALIFICATIONS
- PhD, or Master's degree and 6+ years of applied research experience
- Experience programming in Java, C++, Python or related language
PREFERRED QUALIFICATIONS
- Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc.
- Experience with large scale distributed systems such as Hadoop, Spark etc.
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.
The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.
USA, NY, New York - 183,800.00 - 248,700.00 USD annually
DESCRIPTION
Twitch is looking for an Applied Scientist to lead computer vision and video manipulation work within Amazon Publisher Monetization (APM). You will apply large language models (LLMs), vision-language models (VLMs), and traditional computer vision techniques to build products that directly improve how millions of Twitch creators produce content and how viewers engage with it. This is a high-visibility project backed by senior leadership, and you will have the autonomy to evaluate both first-party and third-party solutions to deliver the highest quality results quickly. If you thrive in a fast-paced, startup-like environment where your scientific decisions shape the product roadmap, we want to hear from you.
Key job responsibilities
Design and deploy computer vision and video manipulation models using LLMs, VLMs, and traditional techniques, taking solutions from research prototype to production.
Partner with senior Product and Twitch leadership to translate customer needs into well-defined scientific problems and deliver end-to-end solutions.
Evaluate and integrate generative AI capabilities across Amazon Bedrock and third-party platforms, selecting the approach that maximizes product quality.
Drive the team's scientific agenda by proposing new initiatives, authoring technical documents, and contributing to external publications.
Mentor fellow scientists and engineers through code reviews, design guidance, and technical assessments that raise the overall quality bar.
A day in the life
You will split your time roughly evenly between independent research and collaborative sessions. Mornings often start with focused solo work — benchmarking a new VLM, writing model code, or analyzing experiment results. Midday you join working sessions with Product and Twitch leadership to align on requirements or review progress. Afternoons shift between pairing with engineers on production integration and mentoring teammates on evaluation methodology. Weekly science reviews and bi-weekly roadmap syncs keep the team aligned without over-scheduling your calendar.
About the team
The APM science team supports all of Amazon's Publisher Monetization efforts, building the models and systems behind Twitch's creator tools and ad experiences. The team includes applied scientists, software engineers, and product managers who collaborate daily to move ideas from whiteboard to production. We operate with a startup mentality — moving fast, wearing multiple hats, and iterating closely with Twitch and Product partners. We are accelerating investment in computer vision and generative AI, and this role will be central to that expansion.
BASIC QUALIFICATIONS
- PhD, or Master's degree and 6+ years of applied research experience
- Experience programming in Java, C++, Python or related language
PREFERRED QUALIFICATIONS
- Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc.
- Experience with large scale distributed systems such as Hadoop, Spark etc.
Amazon is an equal opportunity employer and does not discriminate on the basis of protected veteran status, disability, or other legally protected status.
Our inclusive culture empowers Amazonians to deliver the best results for our customers. If you have a disability and need a workplace accommodation or adjustment during the application and hiring process, including support for the interview or onboarding process, please visit https://amazon.jobs/content/en/how-we-hire/accommodations for more information. If the country/region you’re applying in isn’t listed, please contact your Recruiting Partner.
The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits.
USA, NY, New York - 183,800.00 - 248,700.00 USD annually
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Senior Level Applied Science Manager Jobs: Frequently Asked Questions
How do I get a senior level applied science manager job?
Employers at this level look for candidates who have already owned end-to-end research or applied science initiatives, not just contributed to them. A strong portfolio of shipped models or scientific products, demonstrated experience mentoring scientists or engineers, and the ability to translate complex technical work into business outcomes are what separate competitive applicants. Cross-functional leadership experience and a clear point of view on scientific strategy sharpen your edge further.
Which companies hire senior level applied science managers?
Companies hiring senior level applied science managers right now include Amazon, lululemon, and Embry-Riddle Aeronautical University, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to come from large technology firms, cloud platform providers, healthcare and life sciences organizations, and enterprise software companies with dedicated applied science or machine learning divisions.
Are there remote senior level applied science manager jobs?
Yes, though availability varies by employer and team structure. About 0% of senior level applied science manager openings are remote or hybrid as of November 2026, reflecting strong demand from technology and data-driven organizations that have adopted distributed team models. Fully on-site roles do still exist, particularly at research labs, regulated industries, or companies with large collaborative science teams.
What makes an applied science manager role senior level?
Senior level applied science manager roles are defined by ownership and scope, not just experience. Candidates are expected to set technical direction for a research area or product, make independent decisions on methodology and resource prioritization, and develop the scientists or engineers on their team. The work connects directly to organizational goals, and the manager is accountable for outcomes, not just delivery of assigned tasks.
Which industries hire the most senior level applied science managers?
Senior Level applied science manager roles concentrate in Retail, Education, and Technology & Software, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they invest heavily in proprietary models, data products, and scientific infrastructure that require experienced leadership to build and scale responsibly.