Artificial Intelligence Scientist Jobs in Boston, MA
Artificial Intelligence Scientist jobs in Boston are concentrated in the Longwood Medical Area, Kendall Square, and the Seaport District, driven by strong demand across biotech, academic research, and enterprise technology. Employers hiring right now include XPO, Wayfair, and Genentech. Scan the live roles below and apply to whichever ones fit.
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What you’ll need to succeed as an Applied AI Scientist at XPO:
- Bachelor's degree or equivalent related work or military experience
- 1 year of experience designing evaluation harnesses or benchmarks to rigorously assess model or agent performance against existing baselines
- Hands-on experience building applied AI systems, including one or more of: agent-based/agentic systems, experimentation frameworks, or applying LLM-based/foundation model architectures to time-series forecasting problems
- Proficiency in Python and modern ML/AI frameworks and platforms (e.g. PyTorch, HuggingFace)
- Strong communication skills, with the ability to explain AI system behavior and tradeoffs to technical and business stakeholders, and to collaborate closely with optimization/OR scientists on what constitutes a meaningful model improvement
- Bachelor's degree in Computer Science, AI, Data Science, Engineering, or related field, or equivalent related work or military experience
- Master's degree or PhD in Computer Science, AI, Machine Learning, Statistics, or related field
- 2+ years of experience building agentic systems for production use cases and/or R&D applications
- Experience designing operational safeguards (e.g., automated checks against regressions, runaway compute, or unvalidated models reaching production) for agent-based systems
- Practical experience applying time-series or tabular foundation models (e.g., Chronos or similar) to forecasting problems such as ETA prediction or demand forecasting
- Practical experience with foundation model fine-tuning or post-training techniques
- Practical experience applying reinforcement learning (e.g., RLHF, or RL for agent behavior and decision-making)
- Experience building retrieval-augmented generation (RAG) systems is a plus
- Experience applying agentic or applied AI techniques to logistics, transportation, or operations research domains
About the Applied AI Scientist job:
- Design and build agentic experimentation layer over optimization models developed by the team's OR/data scientists, including proposing variants, running evaluations, and surfacing promising results
- Build evaluation harnesses that rigorously and automatically benchmark model and agent performance against existing baselines before promotion to production
- Implement operational safeguards for autonomous experimentation systems, such as automated regression checks, compute/cost limits, and human-in-the-loop gates before production promotion
- Evaluate and integrate modern LLM-based and foundation model architectures (e.g., Chronos-style time-series models) for ETA prediction and demand forecasting for pickup prediction
- Partner closely with the team's optimization/OR scientists to understand model internals, solver behavior, and what constitutes a meaningful improvement for P&D use cases
- Partner with machine learning engineers on the underlying infrastructure needed to run automated experimentation and evaluation at scale
- Communicate technical approaches and tradeoffs to both technical and business audiences
- Stay current on advances in agentic systems, time-series foundation models, and applied GenAI to guide adoption at XPO
Annual Salary Range: $100,000 to $120,000 Actual compensation may vary due to factors such as experience and skill set. This is an incentive-based position, which may include bonuses, incentive or commission plans.
About XPO
XPO is a top ten global provider of transportation services, with a highly integrated network of people, technology and physical assets. At XPO, we look for employees who like a challenge and can communicate effectively in all situations. We want to leverage your skills and years of experience to drive positive results while ensuring a bright future for yourself and XPO. If you’re looking for a growth opportunity, join us at XPO.
We are proud to be an Equal Opportunity employer. Qualified applicants will receive consideration for employment without regard to race, sex, disability, veteran or other protected status.
All applicants who receive a conditional offer of employment may be required to take and pass a pre-employment drug test.
The above statements are not an exhaustive list of all required responsibilities, duties and skills for this job classification.
Review XPO's candidate privacy statement here.
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Top Industries Hiring
- Insurance
- Law & Legal Services
- Technology & Software
- Distribution & Wholesale
- Healthcare & Medical Services
Artificial Intelligence Scientist Jobs in Boston: Frequently Asked Questions
How do I get a artificial intelligence scientist job in Boston?
Boston's strongest hiring comes from biotech and pharmaceutical companies in the Longwood corridor, research institutions in Kendall Square, and enterprise technology firms in the Seaport District. Candidates with experience in machine learning, natural language processing, or computer vision have the clearest path to interviews. Publishing research, contributing to open-source projects, and building a portfolio of applied work gives you a concrete edge in Boston's research-driven market.
Which companies hire artificial intelligence scientists in Boston?
Employers hiring artificial intelligence scientists in Boston right now include XPO, Wayfair, and Genentech, based on current listings on Migrate Mate as of August 2026. Boston's hiring mix is notably research-heavy, with large academic medical centers, biotech firms, and enterprise software companies all competing for the same AI talent pool.
Are there remote artificial intelligence scientist jobs in Boston?
Yes, though availability varies, since artificial intelligence scientist roles that involve lab systems or specialized hardware tend to require in-person work, while modeling, research, and data pipeline work are frequently done remotely. About 60% of artificial intelligence scientist openings tied to Boston are remote or hybrid as of August 2026, reflecting the city's strong hybrid culture across tech and research employers. Pure research modeling positions show the highest remote flexibility locally.
How can I get a artificial intelligence scientist job in Boston with little or no experience?
The most realistic entry path in Boston is through research assistant or junior machine learning engineer roles at the city's many university-affiliated labs and teaching hospitals, particularly those connected to MIT, Harvard, and the Longwood medical institutions. Entry-level candidates who have completed graduate coursework in AI, contributed to published research, or completed internships at Boston-area biotech or fintech firms are consistently prioritized. Targeting companies with active PhD hiring programs or academic partnerships accelerates the transition from training to employment.
Which industries hire the most artificial intelligence scientists in Boston?
Boston artificial intelligence scientist roles concentrate in Insurance, Law & Legal Services, and Technology & Software, based on current listings on Migrate Mate as of August 2026. Boston's position as a global hub for biomedical research and its dense cluster of research universities create sustained demand across these sectors that outpaces most other U.S. cities.
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