Senior Level Clinical Research Site Manager Jobs
Senior level clinical research site manager jobs place experienced professionals in charge of site strategy, protocol execution, and the clinical operations teams that deliver results. Openings are concentrated across on-site, remote, and hybrid settings in Consulting & Professional Services, Technology & Software, and Healthcare & Medical Services, with employers like Cuhaci Peterson, Carollo Engineers, and Amazon hiring at this level now.
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Showing 5 of 246+ Senior Level Clinical Research Site Manager jobs
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
New to North Carolina. Known for pursuing breakthroughs in medicine.
Ready to join our team?
At AbbVie, we bring together talented people and innovative science to develop medicines that help patients. Now, we’re bringing that commitment to Durham, North Carolina, with a new manufacturing campus that will expand our ability to produce medicines and create opportunities in the Research Triangle.
The campus will integrate advanced manufacturing, laboratory technologies and AI to support the production of immunology, oncology and neuroscience medicines. The first phase will include manufacturing facilities, next-generation laboratories, a warehouse, administrative offices and employee wellness facilities.
To learn more about this investment, please visit https://www.abbvie.com/abbvie-north-carolina-manufacturing.html
We are now recruiting our Project Manager - Construction (Utilities & Site Infrastructure) as part of the core start up team.
In this role, you will:
- Utility systems will include Industrial Utilities (IU) and Clean Utilities (CU) including Domestic Water, Chilled Water, Condenser Water, Heating Hot Water, Plant Steam and Condensate, Electrical Distribution including UPS and Generator backup systems, Compressed Air, Process Waste, Sanitary Waste, Vacuum, Pre-Treated Water, Water for Injection (WFI), Gaseous Delivery (i.e., Nitrogen), Clean Steam, and Clean Compressed Air.
- Manages key design interfaces between SVP and BDS A&E firm(s) to ensure that the Basis of Design for both CU and IU systems are aligned including any pre-treatment steps that may be centralized.
- Manages key design interfaces between SVP and BDS A&E firm(s) and the Balance of Campus (BOC) A&E firm to ensure that clear system boundaries are established.
- In coordination with AbbVie's Startup and CQV group, ensure that utility system preparation for operation steps, i.e., pressure testing, cleaning, descaling, passivation, etc. is included for all CU and IU systems.
- Ensure up-front planning is established for handling feed and waste stream flows for typical utility system preparation for operation steps.
- Evaluate modularization of CU and IU systems during design to ensure that future expansion of utilty systems are accommodated.
- Evaluate skidded systems, off-site fabrication, pipe racks, etc. to ensure fastest installation and startup approach can be delivered.
- Ensure Industrial Use Permit (IUP) requirements for both domestic water inflow and sewer outflow is coordinated throughout the initial design process and that the site IUP is approved in advance of project requirements. Additionaly, ensure that any other environmental and/or permitting considerations are evaluated such as Active Pharmaceutical Ingredient (API) concentrations in effluent.
- Ensure that a common set of utility system engineering specfications and standards are established across the program.
- Establish third-party testing programs for all CU and IU systems and ensure that off-site testing, inspections, reporting, etc. is clearly defined prior to bidding those services.
- Align on long-lead equipment required for early procurement and ensure that equipment specifications and procurement packages are initiated as soon as practicable.
- Working with AbbVie EHS, align on sustainability and energy efficiency requirements as well as establishing a Power Monitoring System.
- Working with AbbVie BTS, ensure that control architecture is aligned for all utility systems.
- Evaluate constructability and sequence of all utility systems to ensure fastest possible beneficial use and qualified operational dates can be achieved.
- Working with the SVP and BDS A&E firm(s) and AbbVie leads for both, ensure that a clearly defined and delineated interface between utility system design scopes are established.
- Working with AbbVie EHS, ensure that safe work plans are established for construction, pre-startup, commissioning and qualification activities are establshed and aligned.
- Manages and controls budget for all utility systems scope.
- Manages and controls schedule for all utility systems scope.
- Manages and controls risk assessments and remediation for all utility systems scope.
Qualifications
You will have a Bachelor’s degree in engineering or a related technical discipline. with 7+ years industry experience with demonstrated experience in project execution and accountability, team and stakeholder influencing and strong communication skills
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
New to North Carolina. Known for pursuing breakthroughs in medicine.
Ready to join our team?
At AbbVie, we bring together talented people and innovative science to develop medicines that help patients. Now, we’re bringing that commitment to Durham, North Carolina, with a new manufacturing campus that will expand our ability to produce medicines and create opportunities in the Research Triangle.
The campus will integrate advanced manufacturing, laboratory technologies and AI to support the production of immunology, oncology and neuroscience medicines. The first phase will include manufacturing facilities, next-generation laboratories, a warehouse, administrative offices and employee wellness facilities.
To learn more about this investment, please visit https://www.abbvie.com/abbvie-north-carolina-manufacturing.html
We are now recruiting our Project Manager - Construction (Utilities & Site Infrastructure) as part of the core start up team.
In this role, you will:
- Utility systems will include Industrial Utilities (IU) and Clean Utilities (CU) including Domestic Water, Chilled Water, Condenser Water, Heating Hot Water, Plant Steam and Condensate, Electrical Distribution including UPS and Generator backup systems, Compressed Air, Process Waste, Sanitary Waste, Vacuum, Pre-Treated Water, Water for Injection (WFI), Gaseous Delivery (i.e., Nitrogen), Clean Steam, and Clean Compressed Air.
- Manages key design interfaces between SVP and BDS A&E firm(s) to ensure that the Basis of Design for both CU and IU systems are aligned including any pre-treatment steps that may be centralized.
- Manages key design interfaces between SVP and BDS A&E firm(s) and the Balance of Campus (BOC) A&E firm to ensure that clear system boundaries are established.
- In coordination with AbbVie's Startup and CQV group, ensure that utility system preparation for operation steps, i.e., pressure testing, cleaning, descaling, passivation, etc. is included for all CU and IU systems.
- Ensure up-front planning is established for handling feed and waste stream flows for typical utility system preparation for operation steps.
- Evaluate modularization of CU and IU systems during design to ensure that future expansion of utilty systems are accommodated.
- Evaluate skidded systems, off-site fabrication, pipe racks, etc. to ensure fastest installation and startup approach can be delivered.
- Ensure Industrial Use Permit (IUP) requirements for both domestic water inflow and sewer outflow is coordinated throughout the initial design process and that the site IUP is approved in advance of project requirements. Additionaly, ensure that any other environmental and/or permitting considerations are evaluated such as Active Pharmaceutical Ingredient (API) concentrations in effluent.
- Ensure that a common set of utility system engineering specfications and standards are established across the program.
- Establish third-party testing programs for all CU and IU systems and ensure that off-site testing, inspections, reporting, etc. is clearly defined prior to bidding those services.
- Align on long-lead equipment required for early procurement and ensure that equipment specifications and procurement packages are initiated as soon as practicable.
- Working with AbbVie EHS, align on sustainability and energy efficiency requirements as well as establishing a Power Monitoring System.
- Working with AbbVie BTS, ensure that control architecture is aligned for all utility systems.
- Evaluate constructability and sequence of all utility systems to ensure fastest possible beneficial use and qualified operational dates can be achieved.
- Working with the SVP and BDS A&E firm(s) and AbbVie leads for both, ensure that a clearly defined and delineated interface between utility system design scopes are established.
- Working with AbbVie EHS, ensure that safe work plans are established for construction, pre-startup, commissioning and qualification activities are establshed and aligned.
- Manages and controls budget for all utility systems scope.
- Manages and controls schedule for all utility systems scope.
- Manages and controls risk assessments and remediation for all utility systems scope.
Qualifications
You will have a Bachelor’s degree in engineering or a related technical discipline. with 7+ years industry experience with demonstrated experience in project execution and accountability, team and stakeholder influencing and strong communication skills
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
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Find JobsSenior Level Clinical Research Site Manager Job Market
Who's Hiring
- Cuhaci Peterson13
- Carollo Engineers13
- Amazon12
- HDR9
- Sun River Health8
Top Industries Hiring
- Consulting & Professional Services55
- Technology & Software48
- Healthcare & Medical Services26
- Construction & Real Estate20
- Electronics & Hardware14
Senior Level Clinical Research Site Manager Jobs: Frequently Asked Questions
How do I get a senior level clinical research site manager job?
Employers at this level look for candidates who have owned site activation, managed complex protocol challenges, and led site staff through full study lifecycles. Demonstrating regulatory inspection readiness, strong sponsor and CRO relationship management, and a history of mentoring junior coordinators gives candidates a clear edge. Tailoring your application to show direct accountability for site performance outcomes, not just task completion, is what separates senior-level candidates from the field.
Which companies hire senior level clinical research site managers?
Companies hiring senior level clinical research site managers right now include Cuhaci Peterson, Carollo Engineers, and Amazon, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes primarily from large academic medical centers, contract research organizations, pharmaceutical sponsors, and specialty site networks that run multi-protocol portfolios and need experienced professionals to lead day-to-day operations.
Are there remote senior level clinical research site manager jobs?
Yes, though many roles retain an on-site or hybrid component given the nature of clinical site oversight. About 32% of senior level clinical research site manager openings are remote or hybrid as of November 2026, reflecting broader flexibility in sponsor-facing oversight and coordination roles where direct patient contact is not required. Fully remote openings tend to involve multi-site oversight or sponsor-side monitoring functions rather than single-site management.
What makes a clinical research site manager role senior level?
Senior level clinical research site manager roles are defined by independent ownership of site-level decisions, accountability for regulatory compliance and audit readiness, and responsibility for mentoring coordinators and junior staff. These professionals lead study startup, manage relationships with sponsors and IRBs with minimal oversight, troubleshoot protocol deviations, and often oversee multiple concurrent studies. The distinction from mid-level roles is breadth of accountability and the expectation of guiding others, not just executing assigned tasks.
Which industries hire the most senior level clinical research site managers?
Senior Level clinical research site manager roles concentrate in Consulting & Professional Services, Technology & Software, and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at the senior level because of their ongoing demand for experienced professionals who can maintain regulatory standards, build sponsor relationships, and scale site operations across complex, high-volume research programs.