Data Science Engineer Jobs in Missouri

Data Science Engineer jobs in Missouri are open across St. Louis, Kansas City, and O'Fallon and other Missouri metros, with employers like Mastercard, Lincoln University of Missouri, and Clayco hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles46+
Top employerMastercard
Top citySt. Louis, MO
Cities hiring10
Work type80% On-site
Top industryTechnology

Showing 5 of 46+ Data Science Engineer jobs

Mastercard
Senior Software Engineer II
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Mastercard
Added 4d ago
Senior Software Engineer II
Mastercard
O'Fallon, Missouri
Software Engineering
Data Engineering
Data Science & Analytics
Data Science
Data Analytics
Backend Engineering
$115k - $184k/yr
On-Site
Bachelor's
10,000+

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Centene
Lead Data Engineers
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Centene
Added 1w ago
Lead Data Engineers
Centene
Clayton, Missouri
Data Science & Analytics
Data Engineering
Quality Assurance & Testing (QA Testing)
Data Science
$146k - $191k/yr
Remote (US)
Bachelor's
10,000+

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Bayer
Principal Research Data Engineer
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Bayer
Added 1w ago
Principal Research Data Engineer
Bayer
St. Louis, Missouri
Data Science & Analytics
Data Engineering
Cloud & DevOps
Quality Assurance & Testing (QA Testing)
Data Science
$142k - $185k/yr
Remote (US)
Master's
10,000+

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Mastercard
Senior Data Engineer
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Mastercard
Added 1w ago
Senior Data Engineer
Mastercard
O'Fallon, Missouri
Data Engineering
Data Science & Analytics
Data Science
Data Analytics
$115k - $184k/yr
On-Site
Bachelor's
10,000+

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YASH Technologies
Senior Machine Learning Engineer
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YASH Technologies
Added 3w ago
Senior Machine Learning Engineer
YASH Technologies
St Louis, Missouri
Data Science & Analytics
Software Engineering
Technical Product & Program Management
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
Hybrid
Bachelor's

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See All 46 Data Science Engineer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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Data Science Engineer Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
12 jobs
Kansas City
10 jobs
O'Fallon
8 jobs
St Louis
5 jobs
Jefferson City
4 jobs
Creve Coeur
2 jobs
Springfield
2 jobs
Acim
1 jobs
Clayton
1 jobs

Data Science Engineer Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Mastercard
    Mastercard8
  • Lincoln University of Missouri
    Lincoln University of Missouri4
  • Clayco
    Clayco3
  • Cushman & Wakefield
    Cushman & Wakefield2
  • NVIDIA
    NVIDIA2

Top Industries Hiring

  • Technology & Software11
  • Construction & Real Estate8
  • Consulting & Professional Services7
  • Education5
  • Biotechnology & Pharmaceuticals2

What Missouri Employers Look For

The qualifications that appear most often in data science engineer jobs across Missouri.

  • Proficiency in Python with experience building production-grade data and ML pipelines
  • Hands-on experience with distributed computing frameworks such as Apache Spark or Flink
  • Experience deploying and monitoring machine learning models in cloud environments like AWS, GCP, or Azure
  • Familiarity with MLOps tooling including feature stores, model registries, and workflow orchestrators
  • Bachelor's or master's degree in computer science, data engineering, statistics, or a related field
  • Experience with containerization and orchestration tools such as Docker and Kubernetes

Data Science Engineer Jobs in Missouri: Frequently Asked Questions

How many data science engineer jobs are there in Missouri?

There are 46+ data science engineer openings in Missouri on Migrate Mate as of June 2026, with the most roles in St. Louis, Kansas City, and O'Fallon. New positions post regularly as employers across Missouri hire.

How much do data science engineers make in Missouri?

Data science engineers in Missouri earn a median of about $97,090 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $58,960 for the lowest 10% to over $151,380 for the top 10%. Pay rises with experience, specialty, and employer.

Which Missouri cities have the most data science engineer jobs?

St. Louis, Kansas City, and O'Fallon have the most data science engineer openings in Missouri right now, with additional roles spread across smaller metros statewide.

Which companies hire data science engineers in Missouri?

Employers hiring data science engineers in Missouri include Mastercard, Lincoln University of Missouri, and Clayco, based on current listings on Migrate Mate as of June 2026.

Are there remote data science engineer jobs in Missouri?

Yes. About 20% of data science engineer openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.

How do I apply for data science engineer jobs in Missouri?

You can apply to data science engineer jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.

See All 46 Data Science Engineer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find Data Science Engineer Jobs