Mid Level Payroll Tax Specialist Jobs
Mid level payroll tax specialist jobs go to professionals ready to own compliance filings end to end, guide junior staff through multi-state tax issues, and resolve agency notices with minimal oversight. 67% of openings are remote or hybrid, concentrated in Staffing & Recruiting, Construction & Real Estate, and Biotechnology & Pharmaceuticals, with employers like Mastercard, Ursus, and ABM Industries hiring at this level now.
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INTRODUCTION
PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life’s moments for children and adults living with a rare disease. At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.
JOB DESCRIPTION SUMMARY
The Payroll Tax Analyst is responsible for the execution of payroll tax compliance and reporting activities across multiple jurisdictions for PTC. This role ensures accurate filings, supports audits (including agency notices), monitors regulatory changes and partners with People Services, Finance, IT, external vendors to maintain compliance and operational integrity. The incumbent will work closely under the supervision of the Associate Director of Payroll Tax to carry out all necessary activities for the administration of tax. The role ensures adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.
Responsibilities
Job Description:
- Act as the subject matter expert for payroll tax-related processes, systems and projects. Work closely with external vendor teams, internal functional teams and IT teams for the global People Services team.
- Manage payroll tax activities typical to the role, including review and oversight of payroll tax withholdings, quarterly and annual payroll tax filings, year-end wage and tax reporting, tax reconciliations and resolution of payroll tax notices and inquiries.
- Partner with internal and external payroll providers to ensure accurate and timely remittance of payroll taxes and compliant reporting to federal, state and local tax authorities.
- Partner with Finance to assist in the review and reconciliation of the payroll tax accounts and payroll-related general ledger activity on a regular basis. Investigate and resolve discrepancies in a timely manner and maintain appropriate supporting documentation.
- Support year-end payroll tax activities, including annual wage and tax reporting, employee tax statement review and distribution, and related reconciliations.
- Manage payroll tax registrations, account maintenance and related documentation in applicable jurisdictions, as needed, in partnership with internal stakeholders and external service providers.
- Research and resolve payroll tax issues, employee tax inquiries and agency correspondence. Work closely with Finance, Legal, HR and external advisors, as needed, to ensure appropriate handling and resolution.
- Prioritize payroll deliverables based on criticality and support multiple internal stakeholders while setting clear expectations regarding payroll timelines, controls and service delivery.
- Provide support for internal and external audits related to payroll tax. Prepare requested documentation and respond to audit queries in a timely manner.
- Identify opportunities for payroll tax process improvements, standardization, automation and enhanced reporting.
- Foster a collaborative work environment, ensure that information is effectively communicated among all team members and that clear guidelines exist for payroll tax standards and procedures. Work collaboratively with internal and external partners to ensure alignment of payroll tax operations and project objectives.
- Performs other tasks and assignments as needed and specified by management.
BASIC QUALIFICATIONS
- Bachelor's degree in a related discipline and a minimum of 3+ years of progressively responsible experience in payroll operations, payroll tax in a pharmaceutical, biotechnology or related environment or equivalent experience and/or education.
- Direct and demonstrated experience working in a complex, multi-state and/or multi-country environment.
- Strong knowledge of payroll processing, payroll controls, payroll compliance requirements and payroll tax matters typical to the role, including tax filings, reconciliations, agency notices and year-end reporting.
- Direct and demonstrated Workday experience, preferably at least 5 years, including experience being part of large, complex, enterprise-wide HRIS and payroll projects.
- Proficiency with Microsoft Office, including advanced Excel skills.
- Excellent verbal and written communication skills.
- Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
- Strong analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
- Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
- Demonstrated attention to detail and ability to handle highly confidential employee and payroll information with discretion.
- Ability to document and maintain payroll tax procedures, controls and supporting documentation in accordance with company policies and compliance requirements.
PREFERRED QUALIFICATIONS
- Experience with payroll systems such as Workday, ADP SmartCompliance and/or OSV.
- Experience working within a U.S.-headquartered company and/or a multi-country corporate environment.
TRAVEL REQUIREMENTS
5-10%
EXPECTED BASE SALARY RANGE
$80,500 - $90,000. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity. In addition to base salary, PTC employees are also eligible for short- and long-term incentives. All eligible employees may also enroll in PTC’s medical, dental, vision, and retirement savings plans.
EEO STATEMENT
PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.
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Top Industries Hiring
- Staffing & Recruiting
- Construction & Real Estate
- Biotechnology & Pharmaceuticals
- Consulting & Professional Services
Mid Level Payroll Tax Specialist Jobs: Frequently Asked Questions
How do I get a mid level payroll tax specialist job?
Position your experience around ownership, not just task completion. Highlight filings you managed independently, multi-state tax accounts you handled, and any agency notices you resolved without escalation. Tailor your resume to show that you understand compliance deadlines and can catch errors before they become penalties. Certifications like the CPP or FPC help signal readiness for this tier.
Which companies hire mid level payroll tax specialists?
Companies hiring mid level payroll tax specialists right now include Mastercard, Ursus, and ABM Industries, based on current listings on Migrate Mate as of November 2026. Mid-size companies and large enterprises with multi-state workforces tend to be the most active hirers at this level, since their payroll complexity justifies a dedicated specialist who can work with limited supervision.
Are there remote mid level payroll tax specialist jobs?
Yes, and the share is substantial. About 67% of mid level payroll tax specialist openings are remote or hybrid as of November 2026, reflecting how much of this work centers on software platforms, agency portals, and digital filings rather than on-site processes. Hybrid roles typically require occasional presence for audits or quarter-end close.
How do I move up to a mid level payroll tax specialist role?
Moving from entry level to mid level takes deliberate expansion of scope. Build fluency in multi-state payroll tax compliance, take ownership of at least one full quarterly or annual filing cycle, and document the results of your work, including error reductions or penalty avoidances. Demonstrating that you can spot issues proactively and handle agency correspondence independently is what distinguishes mid level candidates.
Which industries hire the most mid level payroll tax specialists?
Mid Level payroll tax specialist roles concentrate in Staffing & Recruiting, Construction & Real Estate, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors employ large, distributed workforces subject to complex multi-state withholding and unemployment tax requirements, which creates sustained demand for specialists who can manage compliance without constant guidance.