Senior Level Programmer Jobs
Senior level programmer jobs put experienced engineers in charge of architecture decisions, complex system design, and the technical direction of the teams building them. Roles range across on-site, hybrid, and remote settings in Technology & Software, Consulting & Professional Services, and Fashion & Apparel, with employers like Knoll, SMX Services & Consulting, and HDR hiring at this level now.
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Showing 5 of 18+ Senior Level Programmer jobs
Durham, United States of America | Full time | Home-based | R1577809
Job Title: Principal Statistical Programmer
Position Summary
We are seeking a Principal Statistical Programmer to provide full end‑to‑end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands‑on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support. The Principal Statistical Programmer will serve as a subject matter expert, ensure high‑quality deliverables, and contribute to programming standards and best practices.
Key Responsibilities
- Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
- Lead and perform development and validation of:
- SDTM datasets
- ADaM datasets
- Tables, Listings, and Figures (TLFs)
- Ensure all deliverables are compliant with CDISC standards and regulatory requirements
- Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
- Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
- Contribute to and help maintain programming standards, macros, and validation processes
- Review and approve programming deliverables to ensure accuracy, consistency, and quality
- Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
- Proactively identify risks and propose efficient, compliant solutions within timelines
Required Qualifications
- Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
- Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
- Strong hands‑on experience with:
- SDTM and ADaM dataset development
- TLF programming
- Regulatory submission deliverables
- Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
- In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
- Proven ability to manage complex studies independently from start to finish
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $98,200.00 - $273,200.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.Where you'll work
Home-based
You’ll work remotely, with the flexibility to do your best work from home. Supported by collaborative tools and a global team, you’ll stay connected while enjoying the autonomy and balance that comes with a fully remote role.
Culture
Culture at IQVIA is built on a shared belief: that when people are empowered with better data, smarter technology and deeper expertise, they can change what’s possible for patients. Across every team and every corner of the globe, you’ll find colleagues who genuinely care — about the mission and about each other. That’s what makes this a place where people tend to stay, grow and do the best work of their careers.
Durham, United States of America | Full time | Home-based | R1577809
Job Title: Principal Statistical Programmer
Position Summary
We are seeking a Principal Statistical Programmer to provide full end‑to‑end statistical programming support across clinical development programs. This role requires deep technical expertise, leadership, and hands‑on delivery, covering SDTM, ADaM, TLF development, and regulatory submission support. The Principal Statistical Programmer will serve as a subject matter expert, ensure high‑quality deliverables, and contribute to programming standards and best practices.
Key Responsibilities
- Provide end‑to‑end statistical programming support for clinical studies from study setup through submission
- Lead and perform development and validation of:
- SDTM datasets
- ADaM datasets
- Tables, Listings, and Figures (TLFs)
- Ensure all deliverables are compliant with CDISC standards and regulatory requirements
- Support regulatory submissions (e.g., FDA, EMA), including define.xml, submission‑ready datasets, and reviewer’s guides
- Serve as a Principal‑level programmer, providing technical leadership and guidance to other programmers as needed
- Contribute to and help maintain programming standards, macros, and validation processes
- Review and approve programming deliverables to ensure accuracy, consistency, and quality
- Collaborate closely with Biostatistics, Data Management, Clinical Operations, and Regulatory teams
- Proactively identify risks and propose efficient, compliant solutions within timelines
Required Qualifications
- Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, Life Sciences, or related field
- Extensive experience as a statistical programmer, with demonstrated Principal‑level responsibilities
- Strong hands‑on experience with:
- SDTM and ADaM dataset development
- TLF programming
- Regulatory submission deliverables
- Expert proficiency in base SAS and Advanced SAS with good hands on SAS Macros
- In‑depth knowledge of CDISC standards, regulatory guidelines, and submission requirements
- Proven ability to manage complex studies independently from start to finish
IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com
IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law. https://jobs.iqvia.com/eoe
IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.
The potential base pay range for this role, when annualized, is $98,200.00 - $273,200.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.Where you'll work
Home-based
You’ll work remotely, with the flexibility to do your best work from home. Supported by collaborative tools and a global team, you’ll stay connected while enjoying the autonomy and balance that comes with a fully remote role.
Culture
Culture at IQVIA is built on a shared belief: that when people are empowered with better data, smarter technology and deeper expertise, they can change what’s possible for patients. Across every team and every corner of the globe, you’ll find colleagues who genuinely care — about the mission and about each other. That’s what makes this a place where people tend to stay, grow and do the best work of their careers.
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Senior Level Programmer Jobs: Frequently Asked Questions
How do I get a senior level programmer job?
Senior level programmer roles go to candidates who can demonstrate ownership of large-scale systems, not just contribution to them. Hiring managers look for a portfolio of impactful decisions, experience mentoring other engineers, and the ability to lead technical design from ambiguity to production. Strong candidates also show cross-functional communication skills and a history of solving problems that required coordinating across teams.
Which companies hire senior level programmers?
Companies hiring senior level programmers right now include Knoll, SMX Services & Consulting, and HDR, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes from a wide mix of employers, including large enterprise technology firms, growth-stage software companies, and established organizations modernizing core systems.
Are there remote senior level programmer jobs?
Yes, remote work is well established at the senior level. About 38% of senior level programmer openings are remote or hybrid as of November 2026, reflecting employer confidence in letting experienced engineers work independently. Senior programmers with strong async communication habits and a record of self-directed delivery are competitive for fully remote roles.
What makes a programmer role senior level?
A senior level programmer role is defined by scope and ownership. Senior engineers own systems end to end, make architectural decisions with long-term consequences, and are accountable for outcomes rather than individual tasks. They are expected to mentor junior and mid-level colleagues, drive technical standards, and contribute meaningfully to project planning, not just execution.
Which industries hire the most senior level programmers?
Senior level programmer roles concentrate in Technology & Software, Consulting & Professional Services, and Fashion & Apparel, based on current listings on Migrate Mate as of November 2026. These sectors drive demand because they depend on complex, high-stakes software systems where experienced engineers who can own technical direction and reduce delivery risk are consistently in demand.