Regional General Manager Jobs in South Carolina

Regional General Manager jobs in South Carolina are open across Greenwood, Abbeville, and Edgefield and other South Carolina metros, with employers like Self Regional Healthcare, Aspen Dental, and HDR hiring at every experience level. Find a role that fits below and apply directly.

Find Regional General Manager Jobs

Overview

Open roles275+
Top employerSelf Regional Healthcare
Top cityGreenwood, SC
Cities hiring16
Work type98% On-site
Top industryHealthcare

Showing 5 of 275+ Regional General Manager jobs

Aspen Dental
Regional Manager
We won't show you this job again
Aspen Dental
Added 1mo ago
Regional Manager
Aspen Dental
Myrtle Beach, South Carolina
Business Operations
Project & Program Management
Human Resources
$85k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Aspen Dental
Regional Manager
We won't show you this job again
Aspen Dental
Added 1mo ago
Regional Manager
Aspen Dental
Columbia, South Carolina
Human Resources
Project & Program Management
Business Operations
$85k/yr
On-Site
Bachelor's
10,000+

Have you applied for this role?

Aspen Dental
Regional Manager
We won't show you this job again
Aspen Dental
Added 1mo ago
Regional Manager
Aspen Dental
Charleston, South Carolina
Human Resources
Project & Program Management
Business Operations
$85k/yr
On-Site
Bachelor's
10,000+

Have you applied for this role?

Sunbelt Rentals
Regional Sales Manager
We won't show you this job again
Sunbelt Rentals
Added 3d ago
Regional Sales Manager
Sunbelt Rentals
Fort Mill, South Carolina
$101k - $139k/yr
On-Site
None
10,000+

Have you applied for this role?

Atlas Copco Group
Regional Sales Manager
We won't show you this job again
Atlas Copco Group
Added 6d ago
Regional Sales Manager
Atlas Copco Group
Rock Hill, South Carolina
Sales
Account Management
Customer Service & Support
Hybrid
Bachelor's
5,001-10,000

Have you applied for this role?

See All 275+ Regional General Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Regional General Manager Jobs

Regional General Manager Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Greenwood
202 jobs
Abbeville
40 jobs
Edgefield
8 jobs
Charleston
5 jobs
Columbia
3 jobs
Laurens
3 jobs
Fort Mill
2 jobs
Greenville
2 jobs
Myrtle Beach
2 jobs

Regional General Manager Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

  • Self Regional Healthcare
    Self Regional Healthcare254
  • Aspen Dental
    Aspen Dental3
  • HDR
    HDR3
  • Anywhere Real Estate
    Anywhere Real Estate2
  • Atlas Copco
    Atlas Copco2

Top Industries Hiring

  • Healthcare & Medical Services260
  • Construction & Real Estate3
  • Consulting & Professional Services3
  • Education2
  • Hospitality & Tourism2

What South Carolina Employers Look For

The qualifications that appear most often in regional general manager jobs across South Carolina.

  • 5 or more years of multi-unit or multi-location management experience
  • Demonstrated P&L ownership and budget management across a defined region
  • Experience leading and developing district managers or location-level general managers
  • Strong operational background in the employer's specific industry vertical
  • Proficiency with workforce management, scheduling, and reporting software
  • Bachelor's degree in business administration, operations management, or a related field

Regional General Manager Jobs in South Carolina: Frequently Asked Questions

How many regional general manager jobs are there in South Carolina?

There are 275+ regional general manager openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Greenwood, Abbeville, and Edgefield. New positions post regularly as employers across South Carolina hire.

How much do regional general managers make in South Carolina?

Regional general managers in South Carolina earn a median of about $106,080 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $56,520 for the lowest 10% to over $219,350 for the top 10%. Pay rises with experience, specialty, and employer.

Which South Carolina cities have the most regional general manager jobs?

Greenwood, Abbeville, and Edgefield have the most regional general manager openings in South Carolina right now, with additional roles spread across smaller metros statewide.

Which companies hire regional general managers in South Carolina?

Employers hiring regional general managers in South Carolina include Self Regional Healthcare, Aspen Dental, and HDR, based on current listings on Migrate Mate as of June 2026.

Are there remote regional general manager jobs in South Carolina?

Yes. About 2% of regional general manager openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.

How do I apply for regional general manager jobs in South Carolina?

You can apply to regional general manager jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.

See All 275+ Regional General Manager Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

Find Regional General Manager Jobs