Remote Principal Clinical Research Associate Jobs
Remote principal clinical research associate jobs are in active demand across the U.S., with remote-first sponsors, contract research organizations, and distributed biotech and pharmaceutical teams consistently posting openings. Employers hiring remotely right now include Commence, GitLab, and Zillow. See the openings below and apply to the ones that match your experience.
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Showing 5 of 11+ Remote Principal Clinical Research Associate jobs
Company Overview:
Headquartered in suburban Atlanta, Georgia, Artivion, Inc. is a medical device company focused on developing simple, elegant solutions that address cardiac and vascular surgeons’ most difficult challenges in treating patients with aortic diseases. Artivion’s four major groups of products include: aortic stent grafts, surgical sealants, On-X mechanical heart valves, and implantable cardiac and vascular human tissues. Artivion has over 1,600 employees worldwide with sales representation in over 100 countries. The Company has manufacturing facilities located in Atlanta, Georgia, Austin, Texas and Hechingen, Germany. Additionally, it has sales and distribution offices in various countries throughout Europe, Asia, and South America. For additional information about Artivion, visit our website, www.artivion.com (http://www.artivion.com/).
Position Overview:
Manage assigned departmental projects and tasks in principle areas of responsibility, which are identified below for aortic arch repair technologies, including execution of investigational device exemption (IDE) studies.
Responsibilities:
- Serve as the primary owner of clinical studies, independently overseeing all study activities including stakeholder communication, team leadership, timeline execution, budget management, and issue resolution.
- Act as the main point of contact for assigned studies, leading cross-functional study team meetings and driving accountability across internal and external partners.
- Manage all study vendors, including qualification, onboarding, contract and budget oversight, invoicing, and escalation of operational issues.
- Develop clinical strategy for investigational device exemption (IDE) studies.
- Participate as a core team member, specifically collaborating with Regulatory, Quality, R&D, and Commercial stakeholders.
- Oversee day-to-day site operations at clinical sites to ensure clinical trials are conducted in compliance with protocols, contracts, GCP, and applicable regulatory requirements.
- Lead the development, review, and maintenance of clinical documentation, including protocols, study management plans, informed consent forms, case report forms, SOPs, and study amendments.
- Manage qualification, selection, and operations of study steering and safety committees.
- Plan and support quality initiatives to ensure study readiness for data analyses.
- Support the development of abstracts, manuscripts, and scientific presentations by coordinating with investigators and co-authors.
- Ensure timely preparation and completion of clinical study reports in alignment with regulatory and organizational deadlines.
- Develop and deliver study-related presentations for internal and external audiences.
- Interface with technical representatives, regional managers, and research teams to provide technical training and address clinical or customer-related inquiries.
- Facilitate regulatory submissions, including annual FDA reports and other required regulatory documentation.
- Serve as a reviewer for technical and marketing materials to ensure scientific accuracy and regulatory compliance.
- Collaborate with Quality and Risk Management partners to proactively identify, assess, and mitigate device risks.
- Support site recruitment and selection activities, investigator meetings, and site training initiatives.
- Perform basic statistical analyses to support product lines and clinical decision-making.
- Conduct literature reviews and prepare scientific summaries relevant to product development and clinical strategy.
- Attend national and international surgical and scientific congresses, in person or remotely, as required.
- Perform additional responsibilities, including duties executed at a level above current title, as assigned.
Qualifications:
- Minimum of a Bachelor’s degree, preferably a Master’s degree (in a related field).
- Minimum 10 years’ experience in clinical research or relevant experience, or advanced degree with 8 years’ experience.
- Experience with aortic repair technology (i.e. surgical grafts, endovascular devices) is highly desirable.
- Experience working on IDE studies is highly desirable.
- Experience working at a medical device company is highly desirable.
- Demonstrate project management, critical thinking, and communication skills.
- Demonstrated statistical and computer skills (spreadsheet, relational databases, intermediate to advanced statistical analysis).
- Excellent written and oral communication skills.
- Proficient knowledge of medical terminology.
- Willingness to travel.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
Company Overview:
Headquartered in suburban Atlanta, Georgia, Artivion, Inc. is a medical device company focused on developing simple, elegant solutions that address cardiac and vascular surgeons’ most difficult challenges in treating patients with aortic diseases. Artivion’s four major groups of products include: aortic stent grafts, surgical sealants, On-X mechanical heart valves, and implantable cardiac and vascular human tissues. Artivion has over 1,600 employees worldwide with sales representation in over 100 countries. The Company has manufacturing facilities located in Atlanta, Georgia, Austin, Texas and Hechingen, Germany. Additionally, it has sales and distribution offices in various countries throughout Europe, Asia, and South America. For additional information about Artivion, visit our website, www.artivion.com (http://www.artivion.com/).
Position Overview:
Manage assigned departmental projects and tasks in principle areas of responsibility, which are identified below for aortic arch repair technologies, including execution of investigational device exemption (IDE) studies.
Responsibilities:
- Serve as the primary owner of clinical studies, independently overseeing all study activities including stakeholder communication, team leadership, timeline execution, budget management, and issue resolution.
- Act as the main point of contact for assigned studies, leading cross-functional study team meetings and driving accountability across internal and external partners.
- Manage all study vendors, including qualification, onboarding, contract and budget oversight, invoicing, and escalation of operational issues.
- Develop clinical strategy for investigational device exemption (IDE) studies.
- Participate as a core team member, specifically collaborating with Regulatory, Quality, R&D, and Commercial stakeholders.
- Oversee day-to-day site operations at clinical sites to ensure clinical trials are conducted in compliance with protocols, contracts, GCP, and applicable regulatory requirements.
- Lead the development, review, and maintenance of clinical documentation, including protocols, study management plans, informed consent forms, case report forms, SOPs, and study amendments.
- Manage qualification, selection, and operations of study steering and safety committees.
- Plan and support quality initiatives to ensure study readiness for data analyses.
- Support the development of abstracts, manuscripts, and scientific presentations by coordinating with investigators and co-authors.
- Ensure timely preparation and completion of clinical study reports in alignment with regulatory and organizational deadlines.
- Develop and deliver study-related presentations for internal and external audiences.
- Interface with technical representatives, regional managers, and research teams to provide technical training and address clinical or customer-related inquiries.
- Facilitate regulatory submissions, including annual FDA reports and other required regulatory documentation.
- Serve as a reviewer for technical and marketing materials to ensure scientific accuracy and regulatory compliance.
- Collaborate with Quality and Risk Management partners to proactively identify, assess, and mitigate device risks.
- Support site recruitment and selection activities, investigator meetings, and site training initiatives.
- Perform basic statistical analyses to support product lines and clinical decision-making.
- Conduct literature reviews and prepare scientific summaries relevant to product development and clinical strategy.
- Attend national and international surgical and scientific congresses, in person or remotely, as required.
- Perform additional responsibilities, including duties executed at a level above current title, as assigned.
Qualifications:
- Minimum of a Bachelor’s degree, preferably a Master’s degree (in a related field).
- Minimum 10 years’ experience in clinical research or relevant experience, or advanced degree with 8 years’ experience.
- Experience with aortic repair technology (i.e. surgical grafts, endovascular devices) is highly desirable.
- Experience working on IDE studies is highly desirable.
- Experience working at a medical device company is highly desirable.
- Demonstrate project management, critical thinking, and communication skills.
- Demonstrated statistical and computer skills (spreadsheet, relational databases, intermediate to advanced statistical analysis).
- Excellent written and oral communication skills.
- Proficient knowledge of medical terminology.
- Willingness to travel.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
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Find JobsRemote Principal Clinical Research Associate Job Market
Who's Hiring
Top Industries Hiring
- Technology & Software
- Non-Profit & Social Services
What Employers Look For
The qualifications that appear most often in remote principal clinical research associate jobs.
- Minimum five years of clinical trial monitoring experience as a CRA
- Deep knowledge of ICH-GCP guidelines and FDA regulations for clinical research
- Experience independently managing multiple Phase II through Phase IV investigative sites
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Bachelor's degree in life sciences, nursing, pharmacy, or a related field
- Strong ability to identify, document, and resolve protocol deviations and site non-compliance issues
Tips for Your Remote Principal Clinical Research Associate Job Search
Apply early to remote roles that fit
Migrate Mate lists remote principal clinical research associate openings from across the U.S. in one place. Check for new postings regularly and apply directly to roles that match your therapeutic area experience and monitoring background before competition builds.
Highlight remote monitoring tool proficiency
Call out your hands-on experience with remote monitoring platforms, EDC systems like Medidata Rave or Oracle Clinical, and eTMF tools early in your resume. Remote employers screen for these specifically because site oversight happens almost entirely through these systems.
Demonstrate async communication with written samples
Remote principal CRA hiring often includes a written exercise or asks for monitoring visit report samples. Keep two or three polished, anonymized examples ready that show how you document findings, communicate protocol deviations, and escalate issues clearly without real-time back-and-forth.
Signal independent site management in your experience
Remote employers want evidence you can manage investigator sites, track enrollment, and resolve compliance issues without daily oversight. Quantify the number of sites you've overseen simultaneously and note therapeutic areas where you've operated with high autonomy.
Remote Principal Clinical Research Associate Jobs: Frequently Asked Questions
How do I get a remote principal clinical research associate job?
Target contract research organizations, decentralized trial sponsors, and biotech companies with distributed site management teams, as these employers hire principal clinical research associates remotely most consistently. Remote employers screen heavily for independent site oversight, strong written communication for async study team updates, and demonstrated proficiency with EDC systems and remote monitoring tools. A history of managing sites with minimal in-person supervision gives candidates a clear edge.
Which companies hire remote principal clinical research associates?
Remote principal clinical research associate roles are posted by Commence, GitLab, and Zillow and others right now, based on current remote listings on Migrate Mate as of November 2026. Hiring tends to concentrate at contract research organizations, mid-size biotech sponsors, and pharmaceutical companies that run decentralized or hybrid clinical trials with distributed oversight teams.
Can you get a remote principal clinical research associate job with no experience?
Yes, but remote principal CRA roles at the principal level are competitive and typically require prior site management experience because you're expected to work independently with minimal supervision from day one. Entry paths include building experience as a remote CRA I or II at a CRO, then advancing. Demonstrating strong regulatory knowledge, familiarity with ICH GCP guidelines, and proficiency with remote monitoring platforms can help open doors.
Do you need a degree for remote principal clinical research associate jobs?
Usually, but the field weighs experience and certifications heavily alongside formal education. Most remote employers expect a life sciences, nursing, or health-related degree, though substantial clinical trial experience combined with credentials like ACRP's CCRA or SOCRA's CCRP certification can carry significant weight in the hiring decision.
Which industries hire the most remote principal clinical research associates?
Most remote principal clinical research associate openings sit in Technology & Software and Non-Profit & Social Services, per current remote listings on Migrate Mate as of November 2026. These sectors rely on distributed site management teams to run multi-site trials without requiring full-time on-site presence, making remote principal CRA roles a natural fit for their operating models.
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