Remote Senior Software Engineering Jobs
Remote Senior Software Engineering jobs are open across the U.S. in sectors like fintech, enterprise software, healthtech, and cybersecurity, where distributed engineering teams have become the standard hiring model. Companies leading remote senior software engineering hiring include CVS Health, The Home Depot, and KONG. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 47+ Remote Senior Software Engineering jobs
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
Senior Software Engineer (Platform Engineering)-Remote, USA
Purpose:
The Senior Software Engineer is a hands-on technical leader responsible for architecting and delivering the Java-based services at the core of Ambry's platform modernization. This role ensures technology execution stays aligned with strategic business goals, owning the design and build of Spring Boot microservices that replace legacy monolith functionality. The position drives legacy system refactoring, cloud migration, microservices adoption, and CI/CD maturity across the engineering organization. It safeguards architectural coherence, actively mitigates technical debt, and provides the senior technical judgment needed to keep major initiatives on schedule and operationally sound.
Essential Functions:
- Own the end-to-end architecture, design, and implementation of Java and Spring Boot microservices across the platform.
- Define and evangelize target-state architecture, service boundaries, and upgrade paths, and document them for engineering and stakeholder audiences.
- Lead the decomposition of legacy PHP/Symfony monolith functionality into resilient, independently deployable Java services.
- Design and build AWS-native solutions using ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, and Parameter Store.
- Build and maintain secure REST APIs with robust validation, error handling, authentication, and authorization.
- Drive identity modernization, including OAuth2/OIDC and the LDAP-to-Okta migration.
- Design and optimize data access layers using JPA/Hibernate, including ORM mappings, schema evolution, index strategy, and query tuning.
- Establish engineering standards for unit and integration testing, CI/CD pipelines, observability, logging, and alerting.
- Partner with QA, DevOps, Product, Architecture, and Regulatory teams to deliver compliant, production-ready software.
- Mentor engineers across levels through code review, design review, and knowledge sharing.
- Lead technical planning and execution of complex, multi-sprint initiatives, and surface delivery risk early.
- Troubleshoot and resolve production issues affecting service performance, stability, and reliability.
- Maintain awareness of and compliance with SOX and HIPAA requirements in a regulated healthcare environment.
- Other duties as assigned.
Qualifications:
- 10+ years of professional software engineering experience with a strong backend focus.
- Expert-level proficiency in Java and Spring Boot, with deep experience in distributed systems.
- Demonstrated experience decomposing monolithic applications into microservices.
- Hands-on experience with AWS services (ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, IAM).
- Strong command of REST API design, authentication and authorization patterns, and enterprise integration.
- Strong experience with relational databases (MySQL/Aurora) and ORM frameworks such as Hibernate/JPA, including query tuning.
- Proficiency with Docker, CI/CD pipelines, and cloud-native delivery practices.
- Proven ability to lead technical direction and mentor engineers across levels.
- Bachelor's degree in Computer Science, Software Engineering, or equivalent experience.
- Excellent communication, problem-solving, and architectural decision-making skills.
Preferred:
- Master's degree in Computer Science or a related field.
- Experience in healthcare, genomics, diagnostics, or other regulated environments.
- Experience with Okta or comparable identity providers.
- Working knowledge of PHP/Symfony sufficient to refactor legacy functionality.
- Experience with Kubernetes, Terraform, or comparable infrastructure-as-code tooling.
- Familiarity with Scaled Agile Framework (SAFe) practices.
$130,000-$150,000 USD Annually
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
About Us
Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.
We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives.
Why Work Here?
We’re looking for people who can change the world.
Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
Senior Software Engineer (Platform Engineering)-Remote, USA
Purpose:
The Senior Software Engineer is a hands-on technical leader responsible for architecting and delivering the Java-based services at the core of Ambry's platform modernization. This role ensures technology execution stays aligned with strategic business goals, owning the design and build of Spring Boot microservices that replace legacy monolith functionality. The position drives legacy system refactoring, cloud migration, microservices adoption, and CI/CD maturity across the engineering organization. It safeguards architectural coherence, actively mitigates technical debt, and provides the senior technical judgment needed to keep major initiatives on schedule and operationally sound.
Essential Functions:
- Own the end-to-end architecture, design, and implementation of Java and Spring Boot microservices across the platform.
- Define and evangelize target-state architecture, service boundaries, and upgrade paths, and document them for engineering and stakeholder audiences.
- Lead the decomposition of legacy PHP/Symfony monolith functionality into resilient, independently deployable Java services.
- Design and build AWS-native solutions using ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, and Parameter Store.
- Build and maintain secure REST APIs with robust validation, error handling, authentication, and authorization.
- Drive identity modernization, including OAuth2/OIDC and the LDAP-to-Okta migration.
- Design and optimize data access layers using JPA/Hibernate, including ORM mappings, schema evolution, index strategy, and query tuning.
- Establish engineering standards for unit and integration testing, CI/CD pipelines, observability, logging, and alerting.
- Partner with QA, DevOps, Product, Architecture, and Regulatory teams to deliver compliant, production-ready software.
- Mentor engineers across levels through code review, design review, and knowledge sharing.
- Lead technical planning and execution of complex, multi-sprint initiatives, and surface delivery risk early.
- Troubleshoot and resolve production issues affecting service performance, stability, and reliability.
- Maintain awareness of and compliance with SOX and HIPAA requirements in a regulated healthcare environment.
- Other duties as assigned.
Qualifications:
- 10+ years of professional software engineering experience with a strong backend focus.
- Expert-level proficiency in Java and Spring Boot, with deep experience in distributed systems.
- Demonstrated experience decomposing monolithic applications into microservices.
- Hands-on experience with AWS services (ECS/Fargate, SQS, SNS, S3, Lambda, API Gateway, IAM).
- Strong command of REST API design, authentication and authorization patterns, and enterprise integration.
- Strong experience with relational databases (MySQL/Aurora) and ORM frameworks such as Hibernate/JPA, including query tuning.
- Proficiency with Docker, CI/CD pipelines, and cloud-native delivery practices.
- Proven ability to lead technical direction and mentor engineers across levels.
- Bachelor's degree in Computer Science, Software Engineering, or equivalent experience.
- Excellent communication, problem-solving, and architectural decision-making skills.
Preferred:
- Master's degree in Computer Science or a related field.
- Experience in healthcare, genomics, diagnostics, or other regulated environments.
- Experience with Okta or comparable identity providers.
- Working knowledge of PHP/Symfony sufficient to refactor legacy functionality.
- Experience with Kubernetes, Terraform, or comparable infrastructure-as-code tooling.
- Familiarity with Scaled Agile Framework (SAFe) practices.
$130,000-$150,000 USD Annually
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
About Us
Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.
We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives.
Why Work Here?
We’re looking for people who can change the world.
Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.
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Find JobsRemote Senior Software Engineering Job Market
Who's Hiring
- CVS Health10
- The Home Depot3
- KONG2
- Optum2
- Smartsheet2
Top Industries Hiring
- Technology & Software
- Insurance
What Employers Look For
The qualifications that appear most often in remote senior software engineering jobs.
- Five or more years of professional software engineering experience
- Proficiency in at least one systems or backend language such as Java, Go, Python, or C++
- Demonstrated experience designing distributed systems or microservices architectures
- Strong understanding of cloud platforms such as AWS, GCP, or Azure
- Experience mentoring junior engineers and leading technical projects end to end
- Bachelor's degree in computer science, software engineering, or a related field
Tips for Your Remote Senior Software Engineering Job Search
Apply early to remote roles that fit
Migrate Mate lists remote senior software engineering openings from across the U.S. in one place, so you can find roles that match your stack and apply directly without hunting across multiple sources. Applying within the first few days of a posting increases your chances considerably.
Show async communication skills upfront
Remote engineering teams screen for written clarity before the first interview. Use your cover letter and any take-home prompts to demonstrate how you explain technical decisions in writing, not just what stack you know.
Build a portfolio that proves system ownership
Remote hiring managers want evidence you can own a feature or service end to end. Publish architectural decision records, post-mortems, or case studies from past projects on GitHub or a personal site to make your ownership record visible.
Prepare for distributed-team interview formats
Remote senior software engineering interviews commonly include async coding assessments, system design sessions over video, and written architecture questions. Practice explaining design tradeoffs in clear, structured prose and walking through diagrams verbally without a whiteboard.
Remote Senior Software Engineering Jobs: Frequently Asked Questions
How do I get a remote senior software engineering job?
Remote senior software engineering roles go to candidates who demonstrate they can operate independently, communicate decisions clearly in writing, and ship work without in-person oversight. Remote hiring managers look for strong async communication, experience working across time zones, and a GitHub or portfolio that shows ownership of complex systems. Documenting your architectural decisions and contributing to open-source projects strengthens your case significantly.
Which companies hire remote senior software engineerings?
Employers currently hiring remote senior software engineerings include CVS Health, The Home Depot, and KONG, per current remote listings on Migrate Mate as of September 2026. Remote-first software firms, distributed product teams in fintech and healthtech, and cloud infrastructure companies make up the bulk of remote senior software engineering demand.
Can you get a remote senior software engineering job with no experience?
Yes, but remote entry-level roles in senior software engineering are competitive because employers expect you to troubleshoot and make decisions without a manager nearby. Open-source contributions, contract projects, and a portfolio showing real shipped code substitute for traditional employment history. Remote-first startups and smaller product companies are the most likely to take a chance on candidates with strong fundamentals and demonstrable self-direction.
Do you need a degree for remote senior software engineering jobs?
Not always. Remote employers in software engineering weight demonstrated technical ability, code quality, and system design skill heavily alongside or instead of formal credentials. A strong GitHub profile, verifiable shipped projects, and the ability to pass a technical screen often matter more than a degree, particularly at remote-first product companies and startups evaluating engineers on output.
Which industries hire the most remote senior software engineerings?
The sectors hiring the most remote senior software engineerings are Technology & Software and Insurance, based on current remote listings on Migrate Mate as of September 2026. These industries rely on distributed engineering teams because their products are digital-first and their talent needs are too specialized to limit to a single geography.
See All 47 Remote Senior Software Engineering Jobs
Find roles that match your experience and apply in just a few clicks.
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