Senior Level Scientific Software Engineer Jobs

Senior level scientific software engineer jobs put experienced engineers in charge of architectural decisions, technical strategy, and the cross-functional teams and projects that deliver production-grade scientific computing systems. Roles are predominantly remote and hybrid across Biotechnology & Pharmaceuticals, Food & Beverage, and Science & Research, with employers like Neurocrine Biosciences, Revolution Medicines, and BLN24 hiring at this level now.

Find Jobs

Overview

Open roles12
Top stateCalifornia
Top employerNeurocrine Biosciences
Top citySan Diego, CA
Work type91% On-site
Top industryBiotechnology

Showing 5 of 12+ Senior Level Scientific Software Engineer jobs

Senior Manager, Dairy Scientific and Regulatory Affairs
We won't show you this job again
Added 2w ago
Senior Manager, Dairy Scientific and Regulatory Affairs
fairlife
Chicago, Illinois
Compliance & Legal
Public Health & Informatics
Healthcare Administration
Public Health
Compliance & Risk
$150k/yr
On-Site
Bachelor's

Have you applied for this role?

Scientific Computer Engineer
We won't show you this job again
Added 1mo ago
Scientific Computer Engineer
Revolution Medicines
San Francisco Bay Area
Cloud & DevOps
Data Science & Analytics
Technical Product & Program Management
DevOps
Technical Program Management
$205k/yr
On-Site
Bachelor's

Have you applied for this role?

VP, In Vitro - Scientific Operations
We won't show you this job again
Added 1mo ago
VP, In Vitro - Scientific Operations
Crown Bioscience
Harrisburg, Pennsylvania
Project & Program Management
Healthcare Administration
Project Management
On-Site
Doctorate
1,001-5,000

Have you applied for this role?

Associate Director, Global Scientific Training
We won't show you this job again
Added 2mo ago
Associate Director, Global Scientific Training
Ascendis Pharma
Princeton, New Jersey
Corporate Training & Learning Development
Healthcare Administration
Learning & Development
Corporate Training
$190k - $200k/yr
On-Site
Doctorate

Have you applied for this role?

Senior Scientific Director, Protein Engineering
We won't show you this job again
Added 3mo ago
Senior Scientific Director, Protein Engineering
Neurocrine Biosciences
San Diego, California
Biotech & Life Sciences
Laboratory Research
On-Site
Doctorate

Have you applied for this role?

See All 12 Senior Level Scientific Software Engineer Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs

Senior Level Scientific Software Engineer Job Market

Who's Hiring

Neurocrine Biosciences2 open roles
Revolution Medicines2 open roles
BLN241 open role

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Food & Beverage
  • Science & Research
  • Healthcare & Medical Services

Senior Level Scientific Software Engineer Jobs: Frequently Asked Questions

How do I get a senior level scientific software engineer job?

Employers at this level look for demonstrated ownership of complex scientific software systems, not just contribution to them. Strong candidates bring depth in high-performance computing, numerical methods, or domain-specific simulation frameworks, combined with a history of leading design decisions and mentoring junior engineers. Open-source contributions, published work, or a portfolio of production systems you architected carry significant weight in hiring conversations.

Which companies hire senior level scientific software engineers?

Companies hiring senior level scientific software engineers right now include Neurocrine Biosciences, Revolution Medicines, and BLN24, based on current listings on Migrate Mate as of November 2026. Hiring at this level covers national laboratories, aerospace and defense contractors, life sciences firms, and technology companies building simulation or data-intensive research platforms.

Are there remote senior level scientific software engineer jobs?

Yes, though availability varies by employer and domain. About 9% of senior level scientific software engineer openings are remote or hybrid as of November 2026, reflecting strong demand from technology companies and research organizations that have built distributed engineering teams. Roles tied to classified work, lab instrumentation, or on-site hardware tend to require in-person presence.

What makes a scientific software engineer role senior level?

Senior level scientific software engineer roles are defined by scope and ownership. You are expected to set the technical direction for a system or workstream, make independent architectural decisions, and ensure the reliability and scalability of production scientific software. Mentoring mid-level and junior engineers is a standard expectation, as is collaborating directly with research scientists or principal investigators to translate domain requirements into software design.

Which industries hire the most senior level scientific software engineers?

Senior Level scientific software engineer roles concentrate in Biotechnology & Pharmaceuticals, Food & Beverage, and Science & Research, based on current listings on Migrate Mate as of November 2026. These sectors drive demand because they require production-grade software that can process large-scale experimental data, run complex simulations, or accelerate research workflows at a level that demands deep software engineering expertise alongside scientific domain knowledge.