Senior Full Stack Engineer Jobs in San Francisco, CA
Senior Full Stack Engineer jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with strong demand across enterprise software, fintech, and AI-driven startups. Employers hiring right now include OpenAI, Rippling, and David Joseph & Company. See the openings below and apply to the ones that match your experience.
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Senior Software Engineer (Full-Stack)
Employment Type: Full-time
Work Type: Hybrid
Location: San Francisco
Company: Roger Healthcare
About This Role
We are looking for a Senior Software Engineer with 5+ years of experience to join our small, lean team of ten engineers. We are seeking a candidate with a strong backend focus, startup experience (Pre-seed to Series B), and a passion for healthcare. This individual will be a core team member, taking on significant ownership to help scale our core services and build new Generative AI and LLM-driven workflows.
What Will You Be Doing?
- Build and ship complex backend services and infrastructure that interface with LLMs and Generative AI models.
- Take ownership of zero-to-one projects, from prototyping MVPs to hardening them into scalable, secure, and reliable production systems.
- Help scale our existing, widely adopted products as we launch to more organizations.
- Improve backend architecture, observability, and code quality standards.
- Collaborate within a flat engineering structure, working directly with other engineers and the CTO.
Pay: $144,301.88 - $173,782.91 per year
Work Location: Hybrid remote in San Francisco, CA 94114
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Find JobsSenior Full Stack Engineer Job Market in San Francisco
Who's Hiring
- OpenAI63
- Rippling43
- David Joseph & Company13D
- Atlassian10
- Salesforce10
Top Industries Hiring
- Technology & Software69
- Science & Research33
- Banking & Financial Services7
- Consulting & Professional Services7
- Agriculture & Farming3
Senior Full Stack Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a senior full stack engineer job in San Francisco?
Focus your search on the SoMa and Mission Bay corridors, where enterprise software companies, fintech firms, and AI startups cluster most densely. Employers in San Francisco consistently prioritize full stack depth across both frontend frameworks and backend systems, so demonstrating end-to-end ownership of features, strong system design skills, and cloud platform experience gives candidates a clear edge in this market.
Which companies hire senior full stack engineers in San Francisco?
Employers hiring senior full stack engineers in San Francisco right now include OpenAI, Rippling, and David Joseph & Company, based on current listings on Migrate Mate as of September 2026. San Francisco's mix of late-stage startups, publicly traded tech companies, and established financial services firms creates steady, varied demand for senior full stack talent across the city.
Are there remote senior full stack engineer jobs in San Francisco?
Yes, senior full stack engineering is among the more remote-friendly technical disciplines since most of the work is done on a laptop and can be performed from anywhere. About 61% of senior full stack engineer openings tied to San Francisco are remote or hybrid as of September 2026, with hybrid arrangements most common at fintech and enterprise software employers headquartered in SoMa and the Financial District.
How can I get a senior full stack engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is landing a junior or mid-level full stack role at one of the city's many seed or Series A startups, where small engineering teams give early-career engineers broad exposure and faster advancement. Contributing to open-source projects, building a portfolio on GitHub, and networking through San Francisco's active tech meetup scene in SoMa significantly improve your chances of being noticed by local hiring managers.
Which industries hire the most senior full stack engineers in San Francisco?
The sectors hiring the most senior full stack engineers in San Francisco are Technology & Software, Science & Research, and Banking & Financial Services, based on current listings on Migrate Mate as of September 2026. San Francisco's dense concentration of venture-backed technology companies and regulated financial services firms drives sustained demand for engineers who can own the full product stack.
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