Senior Software Development Engineer Jobs in Cambridge, MA

Senior Software Development Engineer jobs in Cambridge are concentrated in Kendall Square, East Cambridge, and the Alewife corridor, with demand driven by biotech, life sciences software, enterprise SaaS, and AI research firms. Employers actively hiring include Draper, Lila Sciences, and Google. Find a role that fits below and apply directly.

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Overview

Open roles29
Top employerDraper
Work type33% Remote
Top credentialBachelor's degree
Companies hiring13

Showing 5 of 29+ Senior Software Development Engineer jobs

Senior Staff Software Engineer, Uber TL, P2020 Rollouts
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Senior Staff Software Engineer, Uber TL, P2020 Rollouts
Google
Cambridge, Massachusetts
Customer Support
IT Support
Technical Program Management
$262k - $364k/yr
Remote (US)
Bachelor's degree
10,000+

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Senior Software Engineer, AI Native
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Added 1w ago
Senior Software Engineer, AI Native
Cambridge Mobile Telematics
Cambridge, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$139k - $174k/yr
Remote (US)
Bachelor's degree
51-200

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Senior Software Engineer, Search Security Engineering
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Added 1w ago
Senior Software Engineer, Search Security Engineering
Google
Cambridge, Massachusetts
Electrical Engineering
Engineering (Non-Software)
Specialized Engineering
$174k - $252k/yr
Master's degree
10,000+

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Senior Software Engineer, Front End
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Added 1w ago
Senior Software Engineer, Front End
Google
Cambridge, Massachusetts
Electrical Engineering
Engineering (Non-Software)
Specialized Engineering
$174k - $252k/yr
Master's degree
10,000+

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Senior Flight Software Engineer
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Added 1w ago
Senior Flight Software Engineer
Draper
Cambridge, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$63k - $275k/yr
Bachelor's degree in electrical engineering
1,001-5,000

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See All 29 Senior Software Development Engineer Jobs in Cambridge

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Senior Software Development Engineer Job Market in Cambridge

Who's Hiring

Draper5 open roles
Lila Sciences5 open roles
Google4 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Technology & Software
  • Marketing & Advertising

Senior Software Development Engineer Jobs in Cambridge: Frequently Asked Questions

How do I get a senior software development engineer job in Cambridge?

Cambridge's hiring concentrates in Kendall Square's biotech and deep-tech firms, East Cambridge's enterprise software companies, and the Alewife corridor's growing startup cluster. Candidates with experience in distributed systems, cloud-native architecture, or scientific computing have an edge here. Targeting employers in life sciences software and AI research, where Cambridge's ecosystem is densest, gives you the most direct path to senior openings.

Which companies hire senior software development engineers in Cambridge?

Companies currently hiring senior software development engineers in Cambridge include Draper, Lila Sciences, and Google, per current listings on Migrate Mate as of November 2026. Cambridge's employer mix skews toward biotech software platforms, university-affiliated research spinouts, and enterprise SaaS companies, reflecting the city's concentration of research institutions and venture-backed technology firms.

Are there remote senior software development engineer jobs in Cambridge?

Yes, senior software development engineer roles are among the most remote-compatible in technology, given that core work like code review, architecture design, and CI/CD pipeline management requires no physical presence. About 67% of senior software development engineer openings tied to Cambridge are remote or hybrid as of November 2026, with the highest remote flexibility found in backend and platform engineering roles at Cambridge's SaaS and AI companies.

How can I get a senior software development engineer job in Cambridge with little or no experience?

The most realistic entry path in Cambridge is through associate or mid-level software engineer roles at the city's biotech software firms or university-affiliated startups, which often have structured growth tracks. Aiming for engineering roles at Kendall Square companies that value research backgrounds, or contributing to open-source projects connected to MIT or Harvard labs, builds the local credibility that Cambridge hiring managers look for when promoting from within.

Which industries hire the most senior software development engineers in Cambridge?

Most senior software development engineer openings in Cambridge sit in Biotechnology & Pharmaceuticals, Technology & Software, and Marketing & Advertising, per current listings on Migrate Mate as of November 2026. Cambridge's density of biotech companies, AI research labs, and enterprise software firms makes it one of the most active markets for senior engineers who can work at the intersection of scientific computing and scalable software infrastructure.

See All 29 Senior Software Development Engineer Jobs in Cambridge

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