Senior Staff Data Scientist Jobs in Durham, NC
Senior Staff Data Scientist jobs in Durham are concentrated in Research Triangle Park, downtown Durham, and the Chesterfield district, with strong demand across life sciences, health tech, and enterprise analytics. Employers actively hiring include Alcami, Duke Health, and IQVIA. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 53+ Senior Staff Data Scientist jobs
Summary
#LI-Onsite
Location: Durham, USA
This role is based in Durham, USA. Novartis is unable to offer relocation support for this role. Please only apply if this location is accessible for you.
The Technical Research & Development (TRD) Department drives the advancement of the Adeno-associated virus (AAV) and Lentiviral vector (LVV) production platform across multiple development sites and manages the development, scale-up, scale-down, transfer, optimization, and characterization of processes for the clinical manufacturing of Novartis cell gene therapy products.
About the Role
Major accountabilities:
- Designs and executes gene therapy upstream process development studies.
- Supports early development study projects and late-stage process characterization and scaling up studies.
- Analyses and interprets experimental data from process studies with strong statistical mindset.
- Conducts laboratory studies to enhance AAV and LVV manufacturing technologies, capabilities, and processes (such as media development, bioreactor fed-batch and perfusion process development, optimization and scale-up).
- Preforms experiments at different scales to support pre-clinical, clinical and commercial programs.
- Assists the evaluation and introduction of new technologies.
- Authors technical reports and presents results of development studies both internally and externally.
- Collaborate with cross-functional groups to coordinate studies.
- Other related duties as assigned.
Essential Requirements:
- Experience with bioreactor operation including ambr® (15 & 250), bench-top bioreactor, pilot scale bioreactor.
- Proficient in statistical analysis principles and software. Working knowledge and experience with Design of Experiment (DoE).
- Ability to analyze data to make date-driven decisions and further progress development strategies.
- Knowledge of viral gene therapy and previous experience with AAV process development is preferred.
- Excellent team player with good communication skills.
Novartis Compensation Summary:
The salary for this position is expected to range between $73,500.00 - $136,500.00 USD Annual per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a
variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Summary
#LI-Onsite
Location: Durham, USA
This role is based in Durham, USA. Novartis is unable to offer relocation support for this role. Please only apply if this location is accessible for you.
The Technical Research & Development (TRD) Department drives the advancement of the Adeno-associated virus (AAV) and Lentiviral vector (LVV) production platform across multiple development sites and manages the development, scale-up, scale-down, transfer, optimization, and characterization of processes for the clinical manufacturing of Novartis cell gene therapy products.
About the Role
Major accountabilities:
- Designs and executes gene therapy upstream process development studies.
- Supports early development study projects and late-stage process characterization and scaling up studies.
- Analyses and interprets experimental data from process studies with strong statistical mindset.
- Conducts laboratory studies to enhance AAV and LVV manufacturing technologies, capabilities, and processes (such as media development, bioreactor fed-batch and perfusion process development, optimization and scale-up).
- Preforms experiments at different scales to support pre-clinical, clinical and commercial programs.
- Assists the evaluation and introduction of new technologies.
- Authors technical reports and presents results of development studies both internally and externally.
- Collaborate with cross-functional groups to coordinate studies.
- Other related duties as assigned.
Essential Requirements:
- Experience with bioreactor operation including ambr® (15 & 250), bench-top bioreactor, pilot scale bioreactor.
- Proficient in statistical analysis principles and software. Working knowledge and experience with Design of Experiment (DoE).
- Ability to analyze data to make date-driven decisions and further progress development strategies.
- Knowledge of viral gene therapy and previous experience with AAV process development is preferred.
- Excellent team player with good communication skills.
Novartis Compensation Summary:
The salary for this position is expected to range between $73,500.00 - $136,500.00 USD Annual per year. The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards. US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a
variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.
To learn more about the culture, rewards and benefits we offer our people click here.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture
Benefits and Rewards: Learn about all the ways we’ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
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Find JobsSenior Staff Data Scientist Job Market in Durham
Who's Hiring
- Alcami5
- Duke Health5
- IQVIA3
- Syngenta3
- Eli Lilly3
Top Industries Hiring
- Biotechnology & Pharmaceuticals10
- Science & Research9
- Consulting & Professional Services5
- Education3
- Electronics & Hardware3
Senior Staff Data Scientist Jobs in Durham: Frequently Asked Questions
How do I get a senior staff data scientist job in Durham?
Target Durham's dominant sectors: life sciences, health systems, and enterprise software anchored around Research Triangle Park and the Chesterfield innovation corridor. Employers in biopharma, clinical research organizations, and health tech regularly hire at the senior staff level for candidates with strong ML engineering, causal inference, or clinical data experience. Demonstrating familiarity with regulated data environments and cross-functional team leadership gives you a clear edge in this market.
Which companies hire senior staff data scientists in Durham?
Employers hiring senior staff data scientists in Durham right now include Alcami, Duke Health, and IQVIA, based on current listings on Migrate Mate as of July 2026. Durham's hiring landscape is shaped heavily by research-driven organizations in biopharma, academic health systems, and growth-stage tech companies drawn by the Research Triangle's talent concentration.
Are there remote senior staff data scientist jobs in Durham?
Yes, though availability depends on the role: analytical and modeling-focused positions tend to be remote-friendly, while roles requiring hands-on collaboration with lab or clinical teams are more often hybrid or on-site. About 21% of senior staff data scientist openings tied to Durham are remote or hybrid as of July 2026, reflecting broader flexibility across the Research Triangle tech and life sciences corridor. Pure platform and product analytics roles skew most remote locally.
How can I get a senior staff data scientist job in Durham with little or no experience?
The most realistic entry path in Durham is through the research and clinical data pipelines at academic medical centers and contract research organizations, which regularly hire data analysts and junior data scientists as stepping stones. Roles in health data quality, biostatistics support, or ML operations at Durham's biopharma and health tech employers build the domain fluency hiring managers expect at the senior staff level. Open-source contributions in clinical NLP or survival analysis are especially well received locally.
Which industries hire the most senior staff data scientists in Durham?
Most senior staff data scientist openings in Durham sit in Biotechnology & Pharmaceuticals, Science & Research, and Consulting & Professional Services, per current listings on Migrate Mate as of July 2026. Durham's position at the heart of the Research Triangle means life sciences and health technology anchor local demand, with enterprise software and financial analytics firms increasingly competing for the same senior talent pool.
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