Software Applications Engineer Jobs in Boston, MA

Software Applications Engineer jobs in Boston are in strong demand, concentrated in the Seaport District, Kendall Square, and the Financial District across life sciences, enterprise software, and financial technology. Employers actively hiring include Boston Medical Center, InterSystems, and Wonder. See the openings below and apply to the ones that match your experience.

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Overview

Open roles22
Top employerBoston Medical Center
Work type63% On-site
Top credentialBachelor's
Companies hiring19

Showing 5 of 22+ Software Applications Engineer jobs

Boston Medical Center
Applications Analyst II
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Boston Medical Center
Added 2d ago
Applications Analyst II
Boston Medical Center
Boston, Massachusetts
Business Analysis
Healthcare Administration
Business Analyst
$72k - $104k/yr
On-Site
Associate's
5,001-10,000

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Massachusetts General Hospital
Applications Developer I
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Massachusetts General Hospital
Added 3d ago
Applications Developer I
Massachusetts General Hospital
Boston, Massachusetts
Software Engineering
Data Science & Analytics
Technical Product & Program Management
Backend Engineering
$63k - $90k/yr
On-Site
Bachelor's

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S
Senior Software Engineer, Windows/Desktop Applications - Boston, MA, USA
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S
Added 6d ago
Senior Software Engineer, Windows/Desktop Applications - Boston, MA, USA
Speechify
Boston, Massachusetts
Software Engineering
Cloud & DevOps
Backend Engineering
$140k - $200k/yr
Remote (US)

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Accenture
Epic Certified Willow Pharmacy Applications Manager 6355647
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Accenture
Added 1w ago
Epic Certified Willow Pharmacy Applications Manager 6355647
Accenture
Boston, Massachusetts
$90 - $95/hr
Remote (US)
High School
10,000+

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Liberty Mutual Insurance
IT Applications and Operations Support Specialist
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Liberty Mutual Insurance
Added 1w ago
IT Applications and Operations Support Specialist
Liberty Mutual Insurance
Boston, Massachusetts
Healthcare Administration
Clinical Support
Patient Services & Wellbeing
Caregiving & Elderly Support
$67k - $126k/yr
Bachelor's
10,000+

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See All 22 Software Applications Engineer Jobs in Boston

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Software Applications Engineer Job Market in Boston

Who's Hiring

  • Boston Medical Center
    Boston Medical Center3
  • InterSystems
    InterSystems2
  • Wonder
    Wonder1
  • Accenture
    Accenture1
  • HackerOne
    HackerOne1

Top Industries Hiring

  • Healthcare & Medical Services6
  • Technology & Software5
  • Insurance1
  • Medical Devices1
  • Aerospace & Defense1

Software Applications Engineer Jobs in Boston: Frequently Asked Questions

How do I get a software applications engineer job in Boston?

Focus your search on Boston's life sciences corridor, fintech firms in the Financial District, and the enterprise software companies clustered around Kendall Square and the Seaport. Candidates who demonstrate experience integrating applications into regulated or data-intensive environments stand out here. Familiarity with healthcare systems, trading platforms, or biotech workflows gives you a real edge over generalist applicants in this market.

Which companies hire software applications engineers in Boston?

Companies currently hiring software applications engineers in Boston include Boston Medical Center, InterSystems, and Wonder, per current listings on Migrate Mate as of June 2026. Boston's employer mix skews toward established biotech and pharma firms, regional financial institutions, and high-growth enterprise software companies, many of which maintain large engineering teams with ongoing headcount needs.

Are there remote software applications engineer jobs in Boston?

Yes, though availability varies by specialty. Roles focused on software configuration, integration, and application support tend to offer more remote flexibility than positions requiring on-site lab access or hardware interaction. About 37% of software applications engineer openings tied to Boston are remote or hybrid as of June 2026. Cloud integration and enterprise application support roles skew most remote among Boston-based postings.

How can I get a software applications engineer job in Boston with little or no experience?

The most realistic entry path in Boston is through associate applications engineer or technical support engineer roles at mid-size software vendors or biotech companies in the Seaport and Longwood Medical Area. Many Boston employers use these positions as feeders into full applications engineering roles. Hands-on experience with enterprise platforms like Salesforce or SAP, even through coursework or internships, meaningfully strengthens entry-level applications in this market.

Which industries hire the most software applications engineers in Boston?

Most software applications engineer openings in Boston sit in Healthcare & Medical Services, Technology & Software, and Insurance, per current listings on Migrate Mate as of June 2026. Boston's concentration of research hospitals, global biotech headquarters, and asset management firms creates sustained, specialized demand for engineers who can deploy and maintain mission-critical applications across regulated industries.

See All 22 Software Applications Engineer Jobs in Boston

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