Associate Research Scientist Visa Sponsorship Jobs in California
Associate research scientist visa sponsorship jobs in California are concentrated in the San Francisco Bay Area, San Diego, and Los Angeles, where biotech firms like Genentech, Gilead Sciences, and Amgen, pharmaceutical companies, and research universities maintain active hiring pipelines. California's density of R&D-intensive employers makes it one of the most active states for international research talent.
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Get Access To All JobsINTRODUCTION
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES
The primary purpose of this role is to develop and communicate the evidence that establishes product value — including health economic evidence and real-world evidence (RWE)— and to disseminate that evidence in support of healthcare decision-making. The role is global in nature with a primary focus initially on leading development and dissemination of evidence for US stakeholders, while working on global evidence deliverables in a supportive role.
This role requires effective cross-functional collaboration and coordination with Clinical Development, Medical Affairs, Biometrics, Marketing, US & International Market Access, and field teams to maintain consistency of value evidence across markets. The successful candidate will combine rigorous methodological expertise across health economics, outcomes research, and real-world evidence with a demonstrated ability to execute end to end, from strategy development to tactical execution through publication, and will bring strong communication and ability to drive alignment in a fast-paced, matrixed environment.
Responsibilities
- Develop and execute HEOR strategic plans for assigned programs, with primary accountability for US evidence needs, reflecting the input of key stakeholders and aligned with commercial, clinical, medical, and market access plans.
- Design and execute HEOR studies, including economic modeling, real-world evidence, clinical outcomes assessment, indirect treatment comparisons, and systematic literature reviews, to substantiate the product value proposition.
- Design and oversee real-world evidence studies using US claims, electronic health record, registry, and primary data sources, including data source selection, feasibility assessment, and data access and governance.
- Develop economic models and healthcare economic information (HCEI), and train field teams for effective and compliant communication with population-based decision makers.
- Provide input to the design of clinical development programs to ensure appropriate inclusion of design elements and endpoints relevant to payers, clinicians, and patients.
- Lead AMCP dossier development and synthesize health economic and outcomes evidence contributing to global value dossier development.
- Lead the HEOR dissemination strategy in alignment with the overall product communication strategy, including timely publication of abstracts and manuscripts and presentation at scientific congresses.
- Support selected ex-US evidence deliverables, and ensure coordination between US and ex-US evidence in line with the global evidence strategy.
- Collaborate cross-functionally with market access, medical affairs, biometrics, commercial, operations, and clinical development functions to integrate HEOR plans within the broader strategic framework.
- Manage HEOR vendors and consultants, ensuring deliverables meet objectives, quality standards, and timelines.
QUALIFICATIONS AND EXPERIENCE
- Advanced graduate degree (PhD preferred) in a relevant discipline such as health services research, health economics, epidemiology, or public health.
- Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 10 years and a Master’s degree; or a PhD with 7 years experience; or equivalent experience.
- Knowledge of US and global healthcare systems, US payer and global HTA evidence requirements, and clinical development sufficient to define product value propositions, identify evidence gaps, and formulate evidence generation and communication strategies.
- Demonstrated research capability in HEOR study design, analysis, and interpretation, with accountability for the scientific and technical rigor of HEOR deliverables.
- Experience leading economic modeling, evidence synthesis including systematic review and indirect treatment comparison, and observational study design using US real-world data sources.
- Experience developing AMCP dossiers and healthcare economic information for US population-based decision makers, including familiarity with the regulatory and compliance framework governing communication of such information.
- Proven track record of end-to-end project execution, from concept development through publication.
- Ability to execute HEOR projects independently with minimal guidance.
- Excellent communication, presentation, collaboration, and influencing skills across internal and external stakeholders in a multicultural environment.
PREFERRED
- Experience leading HEOR strategy development and execution in support of a product launch is highly preferred.
- Experience in outcomes research in rare disease and/or neurodegenerative therapeutic areas.
- Familiarity with ex-US HTA evidence requirements and experience contributing to global value dossier development.
COMPENSATION
- Salary Range: $139,000.00 to $180,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
INTRODUCTION
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES
The primary purpose of this role is to develop and communicate the evidence that establishes product value — including health economic evidence and real-world evidence (RWE)— and to disseminate that evidence in support of healthcare decision-making. The role is global in nature with a primary focus initially on leading development and dissemination of evidence for US stakeholders, while working on global evidence deliverables in a supportive role.
This role requires effective cross-functional collaboration and coordination with Clinical Development, Medical Affairs, Biometrics, Marketing, US & International Market Access, and field teams to maintain consistency of value evidence across markets. The successful candidate will combine rigorous methodological expertise across health economics, outcomes research, and real-world evidence with a demonstrated ability to execute end to end, from strategy development to tactical execution through publication, and will bring strong communication and ability to drive alignment in a fast-paced, matrixed environment.
Responsibilities
- Develop and execute HEOR strategic plans for assigned programs, with primary accountability for US evidence needs, reflecting the input of key stakeholders and aligned with commercial, clinical, medical, and market access plans.
- Design and execute HEOR studies, including economic modeling, real-world evidence, clinical outcomes assessment, indirect treatment comparisons, and systematic literature reviews, to substantiate the product value proposition.
- Design and oversee real-world evidence studies using US claims, electronic health record, registry, and primary data sources, including data source selection, feasibility assessment, and data access and governance.
- Develop economic models and healthcare economic information (HCEI), and train field teams for effective and compliant communication with population-based decision makers.
- Provide input to the design of clinical development programs to ensure appropriate inclusion of design elements and endpoints relevant to payers, clinicians, and patients.
- Lead AMCP dossier development and synthesize health economic and outcomes evidence contributing to global value dossier development.
- Lead the HEOR dissemination strategy in alignment with the overall product communication strategy, including timely publication of abstracts and manuscripts and presentation at scientific congresses.
- Support selected ex-US evidence deliverables, and ensure coordination between US and ex-US evidence in line with the global evidence strategy.
- Collaborate cross-functionally with market access, medical affairs, biometrics, commercial, operations, and clinical development functions to integrate HEOR plans within the broader strategic framework.
- Manage HEOR vendors and consultants, ensuring deliverables meet objectives, quality standards, and timelines.
QUALIFICATIONS AND EXPERIENCE
- Advanced graduate degree (PhD preferred) in a relevant discipline such as health services research, health economics, epidemiology, or public health.
- Typically requires a minimum of 12 years of related experience with a Bachelor’s degree; or 10 years and a Master’s degree; or a PhD with 7 years experience; or equivalent experience.
- Knowledge of US and global healthcare systems, US payer and global HTA evidence requirements, and clinical development sufficient to define product value propositions, identify evidence gaps, and formulate evidence generation and communication strategies.
- Demonstrated research capability in HEOR study design, analysis, and interpretation, with accountability for the scientific and technical rigor of HEOR deliverables.
- Experience leading economic modeling, evidence synthesis including systematic review and indirect treatment comparison, and observational study design using US real-world data sources.
- Experience developing AMCP dossiers and healthcare economic information for US population-based decision makers, including familiarity with the regulatory and compliance framework governing communication of such information.
- Proven track record of end-to-end project execution, from concept development through publication.
- Ability to execute HEOR projects independently with minimal guidance.
- Excellent communication, presentation, collaboration, and influencing skills across internal and external stakeholders in a multicultural environment.
PREFERRED
- Experience leading HEOR strategy development and execution in support of a product launch is highly preferred.
- Experience in outcomes research in rare disease and/or neurodegenerative therapeutic areas.
- Familiarity with ex-US HTA evidence requirements and experience contributing to global value dossier development.
COMPENSATION
- Salary Range: $139,000.00 to $180,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
Associate Research Scientist Job Roles in California
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Search Associate Research Scientist Jobs in CaliforniaAssociate Research Scientist Jobs in California: Frequently Asked Questions
Which companies in California sponsor visas for associate research scientists?
California's biotech and pharmaceutical sector includes some of the country's most active visa sponsors for research roles. Companies like Genentech, Gilead Sciences, Amgen, Regeneron (with California operations), AbbVie, and Bristol Myers Squibb regularly file sponsorship petitions for associate research scientists. University-affiliated research institutions such as UC San Francisco, UC San Diego, and Stanford also sponsor international researchers, often through both employment-based and exchange visitor pathways.
What visa types realistically fit associate research scientist roles in California?
Associate research scientist roles typically require at least a bachelor's degree in a directly related scientific field, making them specialty occupations. The H-1B visa is the most common path, granting up to three years of initial status, extendable to six, and subject to an annual cap and selection process. The E-3 visa applies to Australian nationals, and the H-1B1 visa covers Chilean and Singaporean nationals. F-1 OPT and STEM OPT are available to recent graduates with STEM-designated degrees, with STEM OPT providing a 24-month extension. Employer-sponsored EB-2 or EB-3 green cards are also pursued by many research scientists seeking permanent residence.
How to find associate research scientist visa sponsorship jobs in California?
Migrate Mate lists California employers with verified visa sponsorship history for research roles, letting you search specifically for associate research scientist positions in cities like San Francisco, San Diego, and Los Angeles. Because Migrate Mate's database is built from confirmed sponsorship filings, you can focus your applications on employers who have already demonstrated willingness to sponsor international candidates in scientific roles, rather than filtering through postings that may not lead to sponsorship.
Which California cities have the most associate research scientist sponsorship jobs?
The San Francisco Bay Area, particularly South San Francisco and San Francisco itself, leads due to its concentration of biotech and life sciences firms. San Diego is a close second, home to a dense cluster of biopharmaceutical companies and research institutions including the Salk Institute and Scripps Research. Los Angeles also has significant activity, driven by university research centers and a growing biopharma presence. These three metro areas account for the large majority of sponsorship filings for research scientist roles in the state.
Are there California-specific factors that affect visa sponsorship for associate research scientists?
California's high concentration of biotechnology, pharmaceutical, and academic research employers creates strong demand for international scientists, and many established companies in the state have experienced in-house immigration teams. However, California's high cost of living affects prevailing wage determinations, which employers must meet under LCA requirements for H-1B, E-3, and H-1B1 visa petitions. University and nonprofit research employers may qualify as cap-exempt H-1B sponsors, which can reduce timeline uncertainty compared to cap-subject corporate employers.
What is the prevailing wage for sponsored associate research scientist jobs in California?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.