Portfolio Director Visa Sponsorship Jobs in Massachusetts
Portfolio director roles in Massachusetts concentrate in Boston's financial district, the Route 128 tech corridor, and Cambridge's life sciences hub. Major employers include Fidelity Investments, State Street, Harvard Management Company, and large healthcare systems like Mass General Brigham. Visa sponsorship is active across fintech, asset management, and biotech sectors.
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Position Summary:
The Associate Director (AD) of Portfolio and Program Management (PPM) sits within the COO’s organization at Vertex and leads programs from Research through early Development. This role will support program teams involved in early research through to candidate preclinical development. The AD will partner with program leads and cross-functional teams to establish cross-functional strategy and plans to ensure execution against program goals.
Key Duties and Responsibilities:
- Support disease strategy development within Research and drive cross-functional decision-making across the drug research and early development lifecycle, ensuring alignment between scientific objectives, portfolio priorities, and organizational goals
- In partnership with the program leader guide research and development (R&D) efforts to establish a high performing and data-driven team that delivers on corporate objectives and priorities
- Support defining the approach and identifying key stakeholders for cross-functional decision-making and issue resolution
- Collaborate and communicate cross-functionally to measure and achieve program goals
- Lead the generation of program assumptions for annual resource allocation and budgeting across research and development functions
- Effectively manage meetings, inclusive of stakeholder management and preparation, communication, and management of action items, decisions and follow-through
- Communicate complex topics to stakeholders through effective storytelling and content creation
- Develop integrated program planning timelines and reporting. Define critical path activities, interdependencies, and anticipate bottlenecks
- Proactively manage project risks, through identification, assessment, mitigation and escalation of gaps, challenges, and potential roadblocks
- Identify, communicate, and manage resource constraints, synergies, and redundancies
- Establish team operating norms and identify opportunities to improve team performance
Work with Portfolio and Program leadership team to build, manage, coach and retain PM staff.
Knowledge and Skills:
- Comprehensive knowledge of project and portfolio management principles, best practices, tools, technology and methods
- Leadership experience managing cross-functional teams
- Excellent written and oral communication skills, including well-developed presentation skills
- Comprehensive pharmaceutical drug discovery and development knowledge across multiple disciplines
- Exceptional organizational skills and an ability to manage multiple priorities
- Strong collaboration skills to effectively interact with internal or external stakeholders at all levels of the organization
- Ability to work in a fast-paced and collaborative environment and manage multiple concurrent projects with a high degree of independence
- Experience in carrying out Risk Analysis, Decision Analysis and Contingency Planning
- A desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families and society
Ability to embody the Vertex Core Values of Uncompromising Commitment to Patients, Fearless Pursuit of Excellence, Innovation is Our Lifeblood, and “We” Wins
Education and Experience:
- Typically requires an advanced degree in Life Sciences or a relevant field, (PhD degree preferred or strong demonstration of equivalent combination of relevant educational and professional training)
- Typically requires 8 years of experience, or the equivalent combination of education and experience
Experience with drug development on cross-functional teams and/or in more than one function
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$162,200 - $243,200
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
- Hybrid: work remotely up to two days per week; or select
- On-Site: work five days per week on-site with ad hoc flexibility
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Hybrid
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
Portfolio Director Job Roles in Massachusetts
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Search Portfolio Director Jobs in MassachusettsPortfolio Director Jobs in Massachusetts: Frequently Asked Questions
Which companies in Massachusetts sponsor visas for portfolio directors?
Boston-area financial institutions and asset managers file the most sponsorship petitions for portfolio director roles in Massachusetts. Fidelity Investments, State Street, Wellington Management, and Putnam Investments have active sponsorship histories in this category. Beyond finance, life sciences companies in Cambridge and the Route 128 corridor, including Biogen and Moderna, sponsor portfolio directors managing product and research portfolios.
Which visa types realistically cover portfolio director roles in Massachusetts?
Portfolio director is a specialty occupation requiring a directly related bachelor's degree, so the H-1B visa is the primary path. Australian nationals can pursue the E-3 visa instead, which has no lottery and a separate annual cap. Chilean and Singaporean nationals may qualify under the H-1B1 visa. Candidates on F-1 OPT can work for up to 12 months post-graduation, with a potential 24-month STEM OPT extension if their degree carries a STEM-designated CIP code. EB-2 and EB-3 green card paths are available for longer-term sponsorship.
How to find portfolio director visa sponsorship jobs in Massachusetts?
Migrate Mate lists Massachusetts employers with verified sponsorship filing history for portfolio director roles, searchable by city and visa type. This lets you focus on Boston, Cambridge, and suburban Route 128 employers who have already sponsored similar positions, rather than applying broadly and asking about sponsorship late in the process. Migrate Mate's database is particularly useful for targeting financial services and life sciences firms that file regularly.
Which Massachusetts cities have the most portfolio director sponsorship opportunities?
Boston concentrates the highest volume of portfolio director sponsorship activity, driven by its density of asset management firms, fintech companies, and large healthcare systems. Cambridge is the second-strongest market, anchored by biotech, venture-backed startups, and university-adjacent organizations. Waltham and Burlington along the Route 128 corridor host mid-to-large technology and medical device companies that also sponsor at the director level.
Are there state-specific factors that affect portfolio director sponsorship in Massachusetts?
Massachusetts has an unusually deep concentration of institutional investors and life sciences employers, which means portfolio director roles here often carry more specialized requirements than in other states, particularly around regulatory compliance, FDA-related portfolio oversight, or quantitative investment strategies. Employers in regulated industries tend to file H-1B petitions through established immigration counsel, making prior sponsorship history a reliable signal of a company's willingness to sponsor future hires at the director level.
What is the prevailing wage for sponsored portfolio director jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.