Principal Research Engineer Visa Sponsorship Jobs in Massachusetts
Principal research engineer jobs in Massachusetts are concentrated among life sciences giants like Biogen, Moderna, and Broad Institute in Cambridge and Boston, alongside defense and aerospace firms in the Route 128 corridor. MIT and Harvard spin-outs continuously generate deep-tech openings. Many of these employers have established visa sponsorship programs for qualified international candidates.
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Overview
Waters Corporation is seeking a Principal AI Solutions Engineer to drive the adoption and integration of artificial intelligence and machine learning across the Global Research organization. This role will be central to transforming how research is conducted by embedding AI/ML directly into diverse scientific and engineering workflows, such as software and algorithm development, CAD engineering design, and the formulation of chemistry experiments. The successful candidate will be able to source and configure AI solutions and initiate new ways of working in order to accelerate discovery, improve productivity, and increase innovation yield across all Waters technologies.
In addition to serving as the senior AI/ML technical authority within Global Research, this individual will act as a Team Lead for key research programs within the Global Research portfolio, providing technical direction, mentoring, and hands‑on leadership for high‑impact, AI‑enabled research initiatives. The role requires close collaboration with scientists and engineers globally and a strong on‑site presence in Milford, MA to enable effective change management and sustained adoption.
Responsibilities
AI/ML Transformation Leadership
- Identify high‑value opportunities where AI/ML can accelerate research, reduce cost, expand design space, or improve decision‑making in Global Research processes
- Source and configure AI/ML capabilities into existing research and engineering workflows, including mechanical and electrical engineering design, chemistry and other scientific research and software and algorithm development
- Support the use of AI/ML to unlock institutional knowledge from internal data and documentation
- Establish best practices, standards, and metrics to ensure successful and measurable AI/ML adoption
- Help establish training materials, documentation, and ongoing learning programs to sustain long‑term capability growth
AI/ML Research Leadership
- Apply advanced techniques such as Bayesian optimization, surrogate modeling, generative modeling, and data‑driven experimental design
- Serve as technical lead or team lead for key AI/ML applied research projects spanning multiple Waters technology platforms
- Mentor scientists, engineers, interns, and members of the AI/ML champion network, spanning Global Research sites in Milford, MA, Wilmslow, UK, and Bangalore, India
QUALIFICATIONS
Education & Experience
- PhD or MS in Machine Learning, Computer Science, Engineering, Physics, Chemistry, or a related quantitative discipline, or equivalent industry experience
- 8+ years of experience applying machine learning in research, engineering, or advanced technology development environments
- 1+ years of experience learning cutting edge AI technologies and optimizing software development, engineering design or other discipline with on market and/or custom AI capabilities
Technical Skills
- Expertise in machine learning and applied data science
- Strong proficiency in Python and common ML frameworks (e.g., PyTorch, TensorFlow, scikit‑learn)
- Experience building end‑to‑end ML pipelines, including data preparation, modeling, validation, and deployment
Leadership & Collaboration
- Demonstrated ability to lead complex technical initiatives and influence senior scientists and engineers
- Strong communication skills, with the ability to explain AI and ML concepts to non‑ML audiences
- Experience mentoring and guiding cross‑functional teams
PREFERRED QUALIFICATIONS
- Experience with scientific instrumentation, chemistry, or life sciences
- Prior experience leveraging AI/ML within R&D organization processes
- Familiarity with change management in technical or research settings
WHY JOIN WATERS
This role offers a unique opportunity to shape the future of research at Waters by enabling AI‑driven discovery and innovation across the Global Research organization. You’ll have a direct impact on time‑to‑market, research productivity, and long‑term technology leadership.
We know that sometimes the perfect candidate does not exist, and that people can be put off applying for a job if they do not fit all the requirements. If you are excited about working for us and have most of the skills or experience we are looking for, please go ahead and apply. You could be just what we need! We believe strongly in the value of diversity and creating supportive, inclusive environments where our colleagues can succeed. As such, Waters is proud to be an Equal Opportunity Employer and is committed to maintaining a diverse and inclusive work environment.
COMPANY DESCRIPTION
Waters Corporation (NYSE:WAT) is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide.
Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time.
KEY WORDS
Machine Learning, Innovation, AI, ML, Research, Engineering
Principal Research Engineer Job Roles in Massachusetts
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Search Principal Research Engineer Jobs in MassachusettsPrincipal Research Engineer Jobs in Massachusetts: Frequently Asked Questions
Which companies sponsor visas for principal research engineers in Massachusetts?
Major sponsors include Biogen, Moderna, and Ginkgo Bioworks in the biotech sector, alongside Amazon Lab126, Google, and Microsoft offices in Cambridge and Boston. Defense contractors such as Raytheon Technologies and MIT Lincoln Laboratory also sponsor principal research engineer roles. These organizations have active LCA filing histories, which you can verify through OFLC public disclosure data for specific positions and wage levels.
Which visa types realistically fit principal research engineer roles in Massachusetts?
The H-1B visa is the most common path, as principal research engineer roles qualify as specialty occupations requiring at least a bachelor's degree in engineering or a closely related field. Canadian and Mexican nationals may qualify for TN visa status under the USMCA Engineer category. Singaporean nationals can explore the H-1B1 visa, and Australian nationals the E-3 visa. Most employers also support EB-2 or EB-3 green card sponsorship for long-term hires. Confirm eligibility specifics with the sponsoring employer and USCIS guidance.
How to find principal research engineer visa sponsorship jobs in Massachusetts?
Migrate Mate lists principal research engineer roles in Massachusetts filtered to employers with verified visa sponsorship histories, so you can target companies already familiar with the LCA and petition process. Search by role and state to surface active openings at biotech, tech, and defense employers across Cambridge, Boston, and the Route 128 corridor. This saves significant time compared to manually screening postings for sponsorship intent.
Which cities in Massachusetts have the most principal research engineer sponsorship jobs?
Cambridge is the primary hub, anchored by Biogen, Moderna, Ginkgo Bioworks, the Broad Institute, and numerous MIT-affiliated spin-outs. Boston's Seaport District and Longwood Medical Area add further concentration in biotech and health-tech. Lexington, Waltham, and Burlington along the Route 128 corridor host defense contractors and semiconductor firms. Worcester and Lowell have growing research footprints through UMass Medical and biomedical device companies.
Are there any Massachusetts-specific considerations for principal research engineers seeking sponsorship?
Massachusetts' dense university ecosystem, particularly MIT, Harvard, and Northeastern, creates a strong pipeline of principal-level research roles tied to sponsored research agreements and technology transfer. Many employers in Cambridge explicitly hire from postdoctoral and research scientist tracks, which can transition into principal engineer designations. Massachusetts also has no state-level visa or licensing barriers specific to research engineering, though regulated industries like medical devices may require additional credentialing independent of visa status.
What is the prevailing wage for sponsored principal research engineer jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.