Clinical Research Nurse Jobs in USA with Visa Sponsorship
Clinical research nurses qualify for H-1B and other work visas as healthcare professionals requiring specialized nursing education and clinical trial expertise. Most positions require a Bachelor of Science in Nursing (BSN) plus research experience, meeting specialty occupation requirements for visa sponsorship. For detailed occupation requirements, see the O*NET profile.
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INTRODUCTION
Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation’s oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.
JOB SUMMARY
Under the direction of the Principal Investigator or designee, the Clinical Research Nurse I is responsible to carry out all delegated tasks related to complex protocols testing investigational drugs, devices, or research interventions. The Clinical Research Nurse I is a member of the team and resource for study protocol conduct acting as a liaison between the SLU School of Medicine (SOM), clinical partners (ex. SSM Health), the Principal Investigator, Institutional Review Board (IRB), and sponsors to ensure good clinical practice standards (GCP) throughout the life cycle of the study.
PRIMARY JOB RESPONSIBILITIES
- Review and abstract medical record information and ensure proper adherence to randomization schema, study drug dosing and administration.
- Screen patients according to study criteria, randomize, enroll, and obtain consent.
- Administratively responsible for scheduling, performing, and/or supervising required study tests.
- Perform nursing assessments of study participants.
- Document and record, in writing or electronically, all study events and protocol related procedures.
- Review clinical system billing charges for accuracy and appropriateness.
- Ensure that all required study event(s) and protocol related data are accurately and efficiently entered in the clinical trial management system.
- Knowledgeable in regulatory and institutional policies and processes; applies appropriately in study documentation, protocol submissions, and standard operating procedures (SOPs).
- Enters and collects study related data and develops per appropriate processes. Ensures accuracy and completeness of data for all studies. Recognizes and reports security of physical and electronic data vulnerabilities.
- Maintains participant-level documentation for all studies, including those that are complex in nature, require access to the EHR or require SLUCare/SSM charge routing. Screen participants for complex studies (e.g., procedural, and interventional studies).
- Conducts visits for complex studies (e.g., procedural, and interventional studies).
- Identifies all adverse events (AEs) and determines whether or not they are reportable. Collaborates with the PI to determine AE attributes, including relatedness to study. Conducts and documents consent for participants for all types of studies, including those that are complex in nature and/or require clinical research orders in EHR.
- Performs other duties as assigned.
KNOWLEDGE, SKILLS & ABILITIES
- Proficiency in electronic medical records and relevant computer software.
- Strong verbal and written communication skills, and attention to detail is essential.
- Ability to work in a team environment to facilitate the integrity of the study and its timely completion.
- Ability to travel to off-site locations.
MINIMUM QUALIFICATIONS
- RN with current registration to practice nursing in St. Louis.
- 3-5 years of relevant nursing experience.
- Current BLS Certification.
- Can easily use computing software and web based applications (e.g., Microsoft Office products and the electronic medical record).
PREFERRED QUALIFICATIONS
Clinical Research experience strongly preferred.
SCHEDULED WEEKLY HOURS:
40
Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.

INTRODUCTION
Who is Saint Louis University? Founded in 1818, Saint Louis University is one of the nation’s oldest and most prestigious Catholic universities. SLU, which also has a campus in Madrid, Spain, is recognized for world-class academics, life-changing research, compassionate health care, and a strong commitment to faith and service.
JOB SUMMARY
Under the direction of the Principal Investigator or designee, the Clinical Research Nurse I is responsible to carry out all delegated tasks related to complex protocols testing investigational drugs, devices, or research interventions. The Clinical Research Nurse I is a member of the team and resource for study protocol conduct acting as a liaison between the SLU School of Medicine (SOM), clinical partners (ex. SSM Health), the Principal Investigator, Institutional Review Board (IRB), and sponsors to ensure good clinical practice standards (GCP) throughout the life cycle of the study.
PRIMARY JOB RESPONSIBILITIES
- Review and abstract medical record information and ensure proper adherence to randomization schema, study drug dosing and administration.
- Screen patients according to study criteria, randomize, enroll, and obtain consent.
- Administratively responsible for scheduling, performing, and/or supervising required study tests.
- Perform nursing assessments of study participants.
- Document and record, in writing or electronically, all study events and protocol related procedures.
- Review clinical system billing charges for accuracy and appropriateness.
- Ensure that all required study event(s) and protocol related data are accurately and efficiently entered in the clinical trial management system.
- Knowledgeable in regulatory and institutional policies and processes; applies appropriately in study documentation, protocol submissions, and standard operating procedures (SOPs).
- Enters and collects study related data and develops per appropriate processes. Ensures accuracy and completeness of data for all studies. Recognizes and reports security of physical and electronic data vulnerabilities.
- Maintains participant-level documentation for all studies, including those that are complex in nature, require access to the EHR or require SLUCare/SSM charge routing. Screen participants for complex studies (e.g., procedural, and interventional studies).
- Conducts visits for complex studies (e.g., procedural, and interventional studies).
- Identifies all adverse events (AEs) and determines whether or not they are reportable. Collaborates with the PI to determine AE attributes, including relatedness to study. Conducts and documents consent for participants for all types of studies, including those that are complex in nature and/or require clinical research orders in EHR.
- Performs other duties as assigned.
KNOWLEDGE, SKILLS & ABILITIES
- Proficiency in electronic medical records and relevant computer software.
- Strong verbal and written communication skills, and attention to detail is essential.
- Ability to work in a team environment to facilitate the integrity of the study and its timely completion.
- Ability to travel to off-site locations.
MINIMUM QUALIFICATIONS
- RN with current registration to practice nursing in St. Louis.
- 3-5 years of relevant nursing experience.
- Current BLS Certification.
- Can easily use computing software and web based applications (e.g., Microsoft Office products and the electronic medical record).
PREFERRED QUALIFICATIONS
Clinical Research experience strongly preferred.
SCHEDULED WEEKLY HOURS:
40
Saint Louis University is an equal opportunity/affirmative action employer. All qualified candidates will receive consideration for the position applied for without regard to race, color, religion, sex, age, national origin, disability, marital status, sexual orientation, military/veteran status, gender identity, or other non-merit factors. If accommodations are needed for completing the application and/or with the interviewing process, please contact Human Resources at 314-977-5847.
How to Get Visa Sponsorship as a Clinical Research Nurse
Target academic medical centers and research hospitals
Universities like Johns Hopkins, Mayo Clinic, and Cleveland Clinic regularly sponsor clinical research nurses. These institutions have dedicated immigration departments and established visa sponsorship processes.
Emphasize clinical trial certification and GCP training
Good Clinical Practice certification and ACRP credentials demonstrate specialized knowledge beyond general nursing. Include specific therapeutic areas like oncology or cardiology clinical trials in applications.
Document your BSN and any advanced nursing degrees
Clinical research nursing clearly requires nursing education plus research methodology knowledge. Your BSN directly relates to patient safety, protocol compliance, and clinical data integrity requirements.
Highlight experience with FDA regulations and protocols
Knowledge of FDA regulations, ICH guidelines, and clinical trial protocols shows specialized expertise. Document experience with Phase I-IV trials, regulatory submissions, or audit preparations.
Consider contract research organizations (CROs)
Companies like IQVIA, Syneos Health, and PPD hire clinical research nurses for multi-site studies. CROs often have more flexible sponsorship policies than traditional healthcare systems.
Network through clinical research associations
Join ACRP (Association of Clinical Research Professionals) and attend conferences. Many sponsored positions come through professional networks rather than public job postings in clinical research.
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Get Access To All JobsFrequently Asked Questions
Does clinical research nursing qualify as a specialty occupation for H-1B?
Yes, clinical research nursing typically qualifies for H-1B as it requires a BSN plus specialized knowledge of clinical trial protocols, FDA regulations, and research methodology. The role combines nursing expertise with research skills that go beyond general bedside nursing practice.
Can I get visa sponsorship with an ADN instead of a BSN?
It's challenging but possible with significant experience. If you have an Associate Degree in Nursing, you'd need extensive clinical research experience to demonstrate specialized knowledge. The 3-for-1 rule allows three years of experience to substitute for one year of education.
Which visa types work best for clinical research nurses?
H-1B is most common for clinical research nurses at hospitals and pharmaceutical companies. TN visa works for Canadian and Mexican nurses with BSN degrees. O-1 is possible for nurses with extraordinary achievements in clinical research or published studies.
Do pharmaceutical companies sponsor clinical research nurses?
Yes, major pharmaceutical companies like Pfizer, Johnson & Johnson, and Merck sponsor clinical research nurses for drug development roles. They typically prefer candidates with experience in specific therapeutic areas and knowledge of their clinical development programs.
What's the approval rate for clinical research nurse H-1B petitions?
Clinical research nurse H-1B petitions generally have good approval rates when properly documented, as the role clearly requires specialized nursing education plus research knowledge. Success depends on demonstrating how the position requires both nursing expertise and clinical trial methodology skills.
What is the prevailing wage requirement for sponsored Clinical Research Nurse jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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