Artificial Intelligence Scientist Jobs in Missouri
Artificial Intelligence Scientist jobs in Missouri are open across St Louis, Jefferson City, and Kansas City and other Missouri metros, with employers like Lincoln University of Missouri, Mastercard, and Scale AI hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
We are seeking an experienced AI Application Architect to design, build, and deploy end to end AI solutions using modern machine learning and generative AI techniques. The role involves working hands on with data, models, and production systems to deliver scalable, reliable AI applications—without reliance on code assist tools such as GitHub Copilot.
ROLE AND RESPONSIBILITIES
- Design, develop, and deploy end to end AI applications from data ingestion to production inference.
- Build data pipelines for data preparation, feature engineering, and model training.
- Select, train, evaluate, and optimize machine learning and deep learning models.
- Develop APIs and services to expose AI models for real time and batch use cases.
- Implement monitoring, logging, and model performance tracking in production.
- Collaborate with product, data, and domain teams to translate business requirements into AI solutions.
- Ensure AI solutions meet enterprise standards for security, scalability, and responsible AI usage.
BASIC QUALIFICATIONS
Required AI Skill Areas (Core – 4 Skills)
- Machine Learning & Model Development
- Strong understanding of supervised and unsupervised learning techniques.
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Familiarity with evaluation metrics and model validation techniques.
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Data Engineering & Feature Engineering
- Hands on experience with data preprocessing, cleaning, and exploratory data analysis.
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Experience using Python libraries such as Pandas and NumPy, along with SQL.
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Generative AI / LLM Based Application Development
- Experience building applications using Large Language Models (LLMs).
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Experience integrating LLM APIs into enterprise applications.
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AI System Design, Deployment & MLOps
- Ability to design scalable AI architectures for training and inference.
- Experience deploying models as APIs or services (e.g., using FastAPI or Flask).
PREFERRED QUALIFICATIONS
Technical Skills
- Strong proficiency in Python.
- Experience with ML/DL frameworks such as PyTorch or TensorFlow.
- Familiarity with REST APIs, microservices, and cloud platforms (GCP).
- Knowledge of model lifecycle management tools (e.g., MLflow – preferred).
AI / LLM / Agentic AI
- Vertex AI / Gemini.
- Agentic AI architecture.
- MCP (Model Context Protocol).
- RAG architecture.
- Vector databases / vector search.
- Embeddings and semantic search.
- Prompt engineering and optimization.
- AI orchestration frameworks.
- Multi-agent workflows.
- Context management strategies.
- AI governance and guardrails.
Backend & API Development
- Java Spring Boot.
- REST APIs / Microservices.
- Security frameworks (OAuth2, JWT, RBAC).
- API Gateway integration.
- Async/event-driven architecture.
- Caching frameworks (Redis/Caffeine).
LOCATION
St Louis, MO (Remote)
JOB TYPE
Long Term Contract
See All 28 Artificial Intelligence Scientist Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsArtificial Intelligence Scientist Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Artificial Intelligence Scientist Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Lincoln University of Missouri4

- Mastercard4

- Scale AI3

- Cushman & Wakefield2

- Shook, Hardy & Bacon LLP2

Top Industries Hiring
- Technology & Software9
- Education3
- Construction & Real Estate2
- Consulting & Professional Services2
- Law & Legal Services2
What Missouri Employers Look For
The qualifications that appear most often in artificial intelligence scientist jobs across Missouri.
- PhD in computer science, machine learning, statistics, or a closely related field
- Deep expertise in PyTorch or TensorFlow for designing and training large-scale models
- Experience publishing research at peer-reviewed venues such as NeurIPS, ICML, or CVPR
- Strong Python programming skills with proficiency in scientific computing libraries
- Hands-on experience with large language models, diffusion models, or reinforcement learning
- Ability to translate research findings into production-ready systems or product features
Artificial Intelligence Scientist Jobs in Missouri: Frequently Asked Questions
How many artificial intelligence scientist jobs are there in Missouri?
There are 28+ artificial intelligence scientist openings in Missouri on Migrate Mate as of June 2026, with the most roles in St Louis, Jefferson City, and Kansas City. New positions post regularly as employers across Missouri hire.
How much do artificial intelligence scientists make in Missouri?
Artificial intelligence scientists in Missouri earn a median of about $127,820 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $73,630 for the lowest 10% to over $200,010 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most artificial intelligence scientist jobs?
St Louis, Jefferson City, and Kansas City have the most artificial intelligence scientist openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire artificial intelligence scientists in Missouri?
Employers hiring artificial intelligence scientists in Missouri include Lincoln University of Missouri, Mastercard, and Scale AI, based on current listings on Migrate Mate as of June 2026.
Are there remote artificial intelligence scientist jobs in Missouri?
Yes. About 18% of artificial intelligence scientist openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for artificial intelligence scientist jobs in Missouri?
You can apply to artificial intelligence scientist jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 28 Artificial Intelligence Scientist Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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