Chief Commercial Officer Jobs in St. Louis, MO

Chief Commercial Officer jobs in St. Louis are concentrated in the Cortex Innovation Community, downtown's central business district, and the Clayton submarket, with demand across healthcare, financial services, and logistics. Employers actively hiring include KBR, SSM Health, and Concordia Plans. Scan the live roles below and apply to whichever ones fit.

Find Chief Commercial Officer Jobs

Overview

Open roles24
Top employerKBR
Work type75% On-site
Top credentialMaster's degree in business administration
Companies hiring20

Showing 5 of 24+ Chief Commercial Officer jobs

Peachtree Group
Chief Engineer
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Peachtree Group
New 1m ago
Chief Engineer
Peachtree Group
St. Louis, Missouri
Health & Safety
Maintenance & Repair
Skilled Trades
1,001-5,000

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US Department of Veterans Affairs
Associate Chief Nurse - Specialty Outpatient
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US Department of Veterans Affairs
New 1m ago
Associate Chief Nurse - Specialty Outpatient
US Department of Veterans Affairs
St. Louis, Missouri
Compensation & Benefits
Human Resources
Human Resources (HR) — Generalist
Learning & Development
On-Site
Doctoral degree
10,000+

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SSM Health
Regional Vice President of Patient Care Services / Regional Chief Nursing Officer
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SSM Health
New 1m ago
Regional Vice President of Patient Care Services / Regional Chief Nursing Officer
SSM Health
St. Louis, Missouri
IT Support
Project Management
Technical Program Management
On-Site
Managed Registered Nurses (RNs)
10,000+

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Shriners Children's
Chief of Staff - Pediatric Orthopedics
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Shriners Children's
New 1m ago
Chief of Staff - Pediatric Orthopedics
Shriners Children's
St. Louis, Missouri
Business Strategy
Corporate Development & M&A
Executive Leadership & C-Suite
Master's degree in business administration
5,001-10,000

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Holiday Inn Express and Suites
Assistant Chief Engineer
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Holiday Inn Express and Suites
New 1m ago
Assistant Chief Engineer
Holiday Inn Express and Suites
St. Louis, Missouri
Maintenance & Repair
Manufacturing Operations
HVAC Certification
11-50

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See All 24 Chief Commercial Officer Jobs in St. Louis

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Chief Commercial Officer Job Market in St. Louis

Who's Hiring

  • KBR
    KBR2
  • SSM Health
    SSM Health2
  • Concordia Plans
    Concordia Plans2
  • US Department of Veterans Affairs
    US Department of Veterans Affairs2
  • ADM
    ADM1

Top Industries Hiring

  • Aerospace & Defense1
  • Healthcare & Medical Services1
  • Consulting & Professional Services1

Chief Commercial Officer Jobs in St. Louis: Frequently Asked Questions

How do I get a chief commercial officer job in St. Louis?

Focus your search on St. Louis's strongest hiring sectors: healthcare systems, regional banks and insurance carriers, logistics and supply chain companies, and the city's growing biotech corridor in the Cortex district. Candidates who stand out locally bring a mix of enterprise sales leadership and P&L ownership. Board-level visibility through organizations like the St. Louis Regional Chamber also gives applicants a practical edge in this relationship-driven market.

Which companies hire chief commercial officers in St. Louis?

Companies currently hiring chief commercial officers in St. Louis include KBR, SSM Health, and Concordia Plans, per current listings on Migrate Mate as of July 2026. St. Louis tends to attract a mix of legacy Fortune 500 corporations, regional healthcare and financial institutions, and mid-market logistics firms, all of which regularly build out senior commercial leadership.

Are there remote chief commercial officer jobs in St. Louis?

Yes, though remote availability is limited given how much of a chief commercial officer's work involves executive stakeholder engagement and cross-functional leadership that happens in person. About 25% of chief commercial officer openings tied to St. Louis are remote or hybrid as of July 2026, with hybrid arrangements being far more common than fully remote. Strategy and market planning duties tend to be the most location-flexible portions of the role.

How can I get a chief commercial officer job in St. Louis with little or no experience?

The most realistic entry path is building a record in a senior sales, revenue operations, or business development director role at a St. Louis-area employer first. Mid-market companies in the region's healthcare technology and financial services sectors frequently promote from within or hire VP-level candidates ready for a step up. Involvement with St. Louis startup accelerators like Arch Grants or Capital Innovators can also surface early-stage CCO opportunities for candidates willing to take on broad commercial scope in exchange for equity.

Which industries hire the most chief commercial officers in St. Louis?

St. Louis chief commercial officer roles concentrate in Aerospace & Defense, Healthcare & Medical Services, and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. St. Louis's position as a regional hub for healthcare, agricultural business, and freight logistics means those sectors consistently generate the highest volume of senior commercial leadership demand in the metro area.

See All 24 Chief Commercial Officer Jobs in St. Louis

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Find Chief Commercial Officer Jobs