Senior Level Clinical Director Jobs
Senior level clinical director jobs place experienced clinicians in charge of program strategy, care quality standards, and the operational teams that deliver outcomes across entire service lines. Openings are a mix of on-site, remote, and hybrid settings, concentrated in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Education, with employers like Revolution Medicines, Revolution Medicines, and Jobot hiring at this level now.
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INTRODUCTION
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
THE OPPORTUNITY
This is a unique opportunity for a Clinical Operations Professional who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in overseeing clinical trials. As a director, you will be responsible for the Contract Research Organization (CRO) oversight, execution, and management of Revolution Medicines (RevMed) clinical trials.
Responsibilities:
- Adhere to Clinical Standard Operating Procedures (SOP) and Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) Guidelines.
- Oversee the successful management of all aspects of clinical trials within timelines and designated program budgets.
- Strategic thought partner on the development, management, and execution of the Clinical Development Plan (CDP) for assigned clinical programs which include timelines, budget, and resource requirements. Ability to identify critical path activities and articulate and mitigate risks to clinical trial conduct.
- Responsible for successful planning and deployment of Clinical Operations staff (potentially including Clinical Program Managers/Clinical Trial Managers/Clinical Trial Assistants, and consultants) for project and non-project related tasks.
- Lead line management responsibilities that include hiring, performance management, career development, and mentorship.
- Manage/oversee CROs and selected study vendors; ensuring all vendors strive to achieve the predetermined program milestones according to budget and timeline, as well as evaluating vendor performance using metrics and KPIs.
- Lead team meetings and collaborate with other functional groups within the company (e.g., Clinical Development, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals.
- Ensure clinical trials maintain an inspection readiness state throughout the lifecycle of the trial.
- Oversee the improvement of processes that will impact clinical trial management and deliverables including contingency plans by maintaining a highly effective Clinical Operations team and building strong relationships with functional leaders.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- RN or Bachelor’s or Master’s degree in biological sciences or health-related field required.
- 15 years direct Clinical Operations experience in the pharmaceutical or biotech industry. Relevant indirect experiences may also meet the requirement.
- Minimum of 9 years of project and first-line management experience.
- Experience in leading and managing global phase 1-3 clinical trials within designated timelines, resources, and budgets.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Experience with vendor management and CRO oversight.
- Ability to perform complex analysis, draw relevant conclusions, and implement appropriate solutions.
- Ability to pivot, be solution-oriented with consideration to long-term impact on clinical trials, responsibilities, and inspection-readiness.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS, EXPERIENCE AND EDUCATION:
- Proven success in collaborating with vendor systems/portals (e.g., eTMF, EDC, IRT, CTMS).
- Oncology experience, early and/or late stage, strongly preferred.
- Knowledge and/or familiarity with Ex-US region(s) clinical trial operations.
- Experience in working with cooperative group studies and investigator sponsored trials preferred.
COMPENSATION
- Base Pay Salary Range: $211,000 - $264,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
INTRODUCTION
Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.
THE OPPORTUNITY
This is a unique opportunity for a Clinical Operations Professional who has innate leadership and organizational skills, technical expertise in clinical oncology drug development in an industry setting, and experience in overseeing clinical trials. As a director, you will be responsible for the Contract Research Organization (CRO) oversight, execution, and management of Revolution Medicines (RevMed) clinical trials.
Responsibilities:
- Adhere to Clinical Standard Operating Procedures (SOP) and Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) Guidelines.
- Oversee the successful management of all aspects of clinical trials within timelines and designated program budgets.
- Strategic thought partner on the development, management, and execution of the Clinical Development Plan (CDP) for assigned clinical programs which include timelines, budget, and resource requirements. Ability to identify critical path activities and articulate and mitigate risks to clinical trial conduct.
- Responsible for successful planning and deployment of Clinical Operations staff (potentially including Clinical Program Managers/Clinical Trial Managers/Clinical Trial Assistants, and consultants) for project and non-project related tasks.
- Lead line management responsibilities that include hiring, performance management, career development, and mentorship.
- Manage/oversee CROs and selected study vendors; ensuring all vendors strive to achieve the predetermined program milestones according to budget and timeline, as well as evaluating vendor performance using metrics and KPIs.
- Lead team meetings and collaborate with other functional groups within the company (e.g., Clinical Development, Regulatory, QA, Finance, Legal, etc.) to achieve clinical study goals.
- Ensure clinical trials maintain an inspection readiness state throughout the lifecycle of the trial.
- Oversee the improvement of processes that will impact clinical trial management and deliverables including contingency plans by maintaining a highly effective Clinical Operations team and building strong relationships with functional leaders.
REQUIRED SKILLS, EXPERIENCE AND EDUCATION:
- RN or Bachelor’s or Master’s degree in biological sciences or health-related field required.
- 15 years direct Clinical Operations experience in the pharmaceutical or biotech industry. Relevant indirect experiences may also meet the requirement.
- Minimum of 9 years of project and first-line management experience.
- Experience in leading and managing global phase 1-3 clinical trials within designated timelines, resources, and budgets.
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP.
- Experience with vendor management and CRO oversight.
- Ability to perform complex analysis, draw relevant conclusions, and implement appropriate solutions.
- Ability to pivot, be solution-oriented with consideration to long-term impact on clinical trials, responsibilities, and inspection-readiness.
- Strong analytical, negotiation, and persuasion skills.
- Ability to deal with time demands, incomplete information, or unexpected events.
- Outstanding organizational skills with the ability to multi-task and prioritize.
- Excellent interpersonal, verbal, and written communication skills.
- Decision-making skills.
- Comfortable in a fast-paced company environment and able to adjust workload based upon changing priorities.
- Demonstrate proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint); MS Project and/or Smartsheet a plus.
- Travel may be required (~25%).
PREFERRED SKILLS, EXPERIENCE AND EDUCATION:
- Proven success in collaborating with vendor systems/portals (e.g., eTMF, EDC, IRT, CTMS).
- Oncology experience, early and/or late stage, strongly preferred.
- Knowledge and/or familiarity with Ex-US region(s) clinical trial operations.
- Experience in working with cooperative group studies and investigator sponsored trials preferred.
COMPENSATION
- Base Pay Salary Range: $211,000 - $264,000 USD
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
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Find JobsSenior Level Clinical Director Job Market
Who's Hiring
- Revolution Medicines31
- Jobot9
- PTC Therapeutics6
- University of Florida5
Top Industries Hiring
- Biotechnology & Pharmaceuticals62
- Healthcare & Medical Services36
- Education20
- Staffing & Recruiting10
- Science & Research7
Senior Level Clinical Director Jobs: Frequently Asked Questions
How do I get a senior level clinical director job?
Employers at this level look for candidates who have already led cross-functional clinical teams, owned quality and compliance outcomes, and driven measurable improvements in patient or program results. A strong application demonstrates strategic thinking alongside hands-on clinical credibility. Tailoring your materials to show scope of accountability, budget oversight experience, and a history of building or mentoring clinical staff gives you a clear edge over generalist applicants.
Which companies hire senior level clinical directors?
Companies hiring senior level clinical directors right now include Revolution Medicines, Revolution Medicines, and Jobot, based on current listings on Migrate Mate as of October 2026. Hiring at this level is driven by health systems, managed care organizations, behavioral health networks, and large multi-site provider groups that need experienced clinical leaders to oversee quality, compliance, and care delivery at scale.
Are there remote senior level clinical director jobs?
Yes, though many roles require at least some on-site presence given the team leadership and regulatory oversight responsibilities involved. About 15% of senior level clinical director openings are remote or hybrid as of October 2026, with fully remote positions most common in utilization management, population health, and payer-side clinical operations roles.
What makes a clinical director role senior level?
Senior level clinical director roles are defined by breadth of ownership and organizational influence. Where mid-level roles manage a program or unit, senior roles set clinical strategy across multiple service lines, own regulatory and accreditation accountability, manage other leaders rather than just frontline staff, and are directly involved in budget planning and executive decision-making. Mentoring clinical managers and shaping department-wide policies are standard expectations at this stage.
Which industries hire the most senior level clinical directors?
Senior Level clinical director roles concentrate in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Education, based on current listings on Migrate Mate as of October 2026. These sectors drive hiring because they operate large, complex care delivery or coverage models that require experienced clinical oversight to maintain quality standards, meet regulatory requirements, and manage outcomes across diverse patient or member populations.