Senior Level Clinical Manager Jobs
Senior level clinical manager jobs place experienced professionals in charge of clinical operations, quality outcomes, and the teams and programs that deliver care at scale. Roles are concentrated in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, with a mix of on-site, hybrid, and remote positions available, and employers like Fresenius Medical Care, Revolution Medicines, and Revolution Medicines hiring at this level now.
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The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
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Who's Hiring
- Fresenius Medical Care19

- Revolution Medicines13

- Katalyst Healthcares & Life Sciences3

- Eikon Therapeutics2

Top Industries Hiring
- Healthcare & Medical Services29
- Biotechnology & Pharmaceuticals21
- Education8
- Science & Research7
- Consulting & Professional Services4
Senior Level Clinical Manager Jobs: Frequently Asked Questions
How do I get a senior level clinical manager job?
Employers hiring at this level look for candidates who have led clinical teams, owned quality or compliance programs, and driven measurable outcomes across a department or facility. A record of cross-functional leadership, budget or resource oversight, and experience mentoring staff gives candidates a clear edge. Tailoring your application to show scope of responsibility, not just task execution, is what separates senior-level candidates from mid-level ones.
Which companies hire senior level clinical managers?
Companies hiring senior level clinical managers right now include Fresenius Medical Care, Revolution Medicines, and Revolution Medicines, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes from a broad range of employers, including health systems, managed care organizations, specialty clinics, and healthcare technology companies seeking experienced clinical leaders.
Are there remote senior level clinical manager jobs?
Yes, though many senior clinical manager roles require on-site or hybrid presence given the oversight responsibilities involved. About 23% of senior level clinical manager openings are remote or hybrid as of August 2026, with remote positions most common in utilization management, care coordination, and health plan operations roles.
What makes a clinical manager role senior level?
Senior level clinical manager roles are defined by broader scope, greater autonomy, and accountability for strategic outcomes rather than day-to-day task management. Expectations include owning departmental performance, leading and developing other clinical staff, managing budgets or compliance programs, and contributing to organizational-level initiatives. The role typically requires deep domain expertise and the ability to operate without close supervision.
Which industries hire the most senior level clinical managers?
Senior level clinical manager roles concentrate in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, based on current listings on Migrate Mate as of August 2026. These sectors drive hiring at this level because they operate complex, regulated clinical environments that require experienced professionals to maintain quality standards, lead multidisciplinary teams, and ensure compliance across programs or facilities.