Clinical Operations Lead Jobs in South Dakota

Clinical Operations Lead jobs in South Dakota are open across Rapid City, Sioux Falls, and Aberdeen and other South Dakota metros, with employers like Monument Health, Sanford Health, and Sioux Center Health hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles90+
Top employerMonument Health
Top cityRapid City, SD
Cities hiring22
Work type100% On-site
Top industryHealthcare

Showing 5 of 90+ Clinical Operations Lead jobs

Sanford Health
Clinical Care Leader
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Sanford Health
Added 1w ago
Clinical Care Leader
Sanford Health
Sioux Falls, South Dakota
Nursing
Healthcare Administration
Patient Services & Wellbeing
$36 - $55/hr
On-Site
Bachelor's
10,000+

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Sanford Health
Clinical Care Leader
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Sanford Health
Added 1mo ago
Clinical Care Leader
Sanford Health
Sioux Falls, South Dakota
Nursing
Healthcare Administration
Patient Services & Wellbeing
$36 - $55/hr
On-Site
Bachelor's
10,000+

Have you applied for this role?

Sanford Bismarck
RN Clinical Care Leader - FT - LTC - SF Village
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Sanford Bismarck
Added 1mo ago
RN Clinical Care Leader - FT - LTC - SF Village
Sanford Bismarck
Sd, South Dakota
On-Site
Associate's

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Pipestone
Technical Services Lead
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Pipestone
Added 1mo ago
Technical Services Lead
Pipestone
Sioux Falls, South Dakota
Laboratory Research
Biotech & Life Sciences
Clinical Support
Animal Care & Husbandry
$50k - $60k/yr
On-Site
Bachelor's
1,001-5,000

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Monument Health
Respiratory Care Clinical Quality Educator
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Monument Health
New 59m ago
Respiratory Care Clinical Quality Educator
Monument Health
Rapid City, South Dakota
Healthcare Administration
Clinical Support
Corporate Training & Learning Development
Learning & Development
$33 - $42/hr
On-Site
Associate's

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See All 90 Clinical Operations Lead Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

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Clinical Operations Lead Jobs by City in South Dakota

Where South Dakota roles are concentrated, by current openings.

Rapid City
29 jobs
Sioux Falls
26 jobs
Aberdeen
5 jobs
Spearfish
4 jobs
Custer
3 jobs
Parkston
3 jobs
Sd
3 jobs
Mitchell
2 jobs
Pierre
2 jobs

Clinical Operations Lead Job Market in South Dakota

A snapshot from current South Dakota openings, updated as new roles post.

Who's Hiring

  • Monument Health
    Monument Health30
  • Sanford Health
    Sanford Health28
  • Sioux Center Health
    Sioux Center Health15
  • Sanford Bismarck
    Sanford Bismarck5
  • NVA
    NVA4

Top Industries Hiring

  • Healthcare & Medical Services80
  • Non-Profit & Social Services5
  • Animal Care & Pet Services4
  • Agriculture & Farming3
  • Science & Research1

What South Dakota Employers Look For

The qualifications that appear most often in clinical operations lead jobs across South Dakota.

  • Bachelor's degree in life sciences, nursing, or a related field required
  • Minimum five years of clinical trial management or site oversight experience
  • Demonstrated knowledge of ICH E6 GCP guidelines and FDA regulations
  • Proficiency with clinical trial management systems such as Medidata Rave or Veeva Vault
  • Experience managing cross-functional teams across CROs and sponsor organizations
  • Project Management Professional or Clinical Research Associate certification preferred

Clinical Operations Lead Jobs in South Dakota: Frequently Asked Questions

How many clinical operations lead jobs are there in South Dakota?

There are 90+ clinical operations lead openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Rapid City, Sioux Falls, and Aberdeen. New positions post regularly as employers across South Dakota hire.

Which South Dakota cities have the most clinical operations lead jobs?

Rapid City, Sioux Falls, and Aberdeen have the most clinical operations lead openings in South Dakota right now, with additional roles spread across smaller metros statewide.

Which companies hire clinical operations leads in South Dakota?

Employers hiring clinical operations leads in South Dakota include Monument Health, Sanford Health, and Sioux Center Health, based on current listings on Migrate Mate as of June 2026.

Are there remote clinical operations lead jobs in South Dakota?

Yes. About 0% of clinical operations lead openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.

How do I apply for clinical operations lead jobs in South Dakota?

You can apply to clinical operations lead jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.

See All 90 Clinical Operations Lead Jobs in South Dakota

Find roles in South Dakota that match your experience and apply in just a few clicks.

Find Clinical Operations Lead Jobs