Clinical Operations Lead Jobs
Clinical Operations Lead jobs are open across pharmaceutical, biotech, medical device, and contract research organizations, at levels from associate lead to senior and director, with specializations in clinical trials, site management, and regulatory compliance. Find a role that fits from the openings below and apply directly.
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El Camino Health is committed to hiring, retaining and growing the best and brightest professionals who will carry our mission and vision forward. We are proud of our reputation in the community: One built on compassion, innovation, collaboration and delivering high-quality care. Come join the team that makes this happen.
Applicants MUST apply for position(s) by submitting a separate application for each individual job posting number they are interested in being considered for.
FTE
0.5Scheduled Bi-Weekly Hours
40Work Shift
Day: 8 hoursJob Description
The Clinical Data Specialist will serve as a technical resource for collection, entry, analysis, verification and reporting of clinical outcomes and quality data. Prepares, maintains and distributes regular and ad hoc statistical reports. The Clinical Data Specialist works with the Service Line Director and project collaborators to perform data collection and extraction of data sets and reports for Service Line-wide databases, registries and hospital systems. Serves as a member of the Service Line performance improvement team, attending committee meetings as assigned, in ensuring quality data collection and reporting.
Qualifications
Bachelor’s required,
Minimum two years in a job with related job responsibilities.
At least two (2) years clinical data experience preferred.
Demonstrated project management experience and excellent communication skills.
Background in both data management and analytical skills in healthcare environment.
Acute healthcarereporting experience preferred.
Experience with Epic Systems preferred.
License/Certification/Registration Requirements
Ages of Patients Served
This position does not generally require contact with patients.
Salary Range:
The Physical Requirements and Working Conditions of this job are available. El Camino Health will provide reasonable accommodations to qualified individuals with a disability if that will allow them to perform the essential functions of a job unless doing so creates an undue hardship for the hospital, or causes a direct threat to these individuals or others in the workplace which cannot be eliminated by reasonable accommodation.
Sedentary Work - Duties performed mostly while sitting; walking and standing at times. Occasionally lift or carry up to 10 lbs. Uses hands and fingers. - (Physical Requirements-United States of America)
An Equal Opportunity Employer:
El Camino Health seeks and values a diverse workforce. The organization is an equal opportunity employer and makes employment decisions on the basis of qualifications and competencies. El Camino Health prohibits discrimination in employment based on race, ancestry, national origin, color, sex, sexual orientation, gender identity, religion, disability, marital status, age, medical condition or any other status protected by law. In addition to state and federal law, El Camino Health also follows all applicable fair and equitable employment policies from the County of Santa Clara.
Clinical Operations Lead Jobs by Experience Level
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Find Clinical Operations Lead JobsClinical Operations Lead Job Market
Who's Hiring



Top Industries Hiring
- Science & Research
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Medical Devices
What Employers Look For
The qualifications that appear most often in clinical operations lead jobs.
- Bachelor's degree in life sciences, nursing, or a related field required
- Minimum five years of clinical trial management or site oversight experience
- Demonstrated knowledge of ICH E6 GCP guidelines and FDA regulations
- Proficiency with clinical trial management systems such as Medidata Rave or Veeva Vault
- Experience managing cross-functional teams across CROs and sponsor organizations
- Project Management Professional or Clinical Research Associate certification preferred
Tips for Your Clinical Operations Lead Job Search
Quantify your trial oversight on your resume
Hiring managers want to see the scope of your clinical work, not just your job duties. List the number of sites you managed, therapeutic areas covered, and whether you led Phase I through III trials. Concrete scope signals credibility faster than titles alone.
Highlight your regulatory documentation experience
Clinical operations leads are expected to own TMF maintenance, protocol deviations, and audit readiness. Call out specific systems you've used, like Veeva Vault or eTMF platforms, and any FDA or ICH E6 GCP audit experience. Vague mentions of 'regulatory knowledge' won't cut it.
Apply early to roles that fit
Migrate Mate lists clinical operations lead openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target openings by therapeutic area match
Oncology, rare disease, and neurology trials have distinct operational demands. Filter for postings that match your therapeutic background, since hiring teams consistently prioritize candidates who've worked in the same indication over those with broader but shallower experience.
Prepare case studies for your interview panel
Most clinical operations lead interviews include a scenario round covering site escalations, enrollment delays, or vendor management failures. Walk into it with two or three real examples that show how you identified the issue, what you decided, and what the outcome was.
Negotiate beyond base salary at offer stage
Clinical operations leads frequently overlook sign-on bonuses, remote flexibility, and conference budgets when reviewing offers. Ask specifically about trial travel expectations and reimbursement policy, since site visit frequency varies widely and affects your actual take-home value.
Clinical Operations Lead Jobs: Frequently Asked Questions
Which companies are hiring the most clinical operations leads?
The companies hiring the most clinical operations leads right now include MannKind Corporation, Takeda Pharmaceuticals, and Southeast Permanente Medical, with the largest share of openings in California, Massachusetts, and Florida, based on current listings on Migrate Mate as of August 2026. Large CROs, mid-size biotech sponsors, and integrated health systems tend to post the most consistently throughout the year.
How many clinical operations lead jobs are remote?
About 55% of clinical operations lead openings are fully remote or hybrid as of August 2026, with the balance requiring on-site or travel-heavy schedules. Roles focused on oversight, vendor management, and central monitoring tend to offer the most remote flexibility, while site-based and early-phase positions typically require in-person presence.
How do you become a clinical operations lead?
You typically start as a clinical research associate or trial coordinator, building direct site management experience across multiple phases and therapeutic areas. From there, you move into a senior CRA or lead CRA role before stepping into operational leadership. Earning GCP certification and demonstrating cross-functional project ownership, including budget and vendor management, accelerates the progression.
Can you get a clinical operations lead role with limited experience?
Breaking in with limited experience is possible if you've managed at least one trial from startup through closeout, even in a supporting capacity. Emphasize any protocol deviation management, site escalation ownership, or cross-functional coordination you've led. Targeting smaller sponsors or niche CROs in less competitive therapeutic areas gives you the best entry point into a lead title.
What does the clinical operations lead interview process look like?
Most processes run three to four rounds. The first is a recruiter screen covering your trial background and leadership scope. A hiring manager interview follows, focused on operational decision-making and regulatory knowledge. You'll likely face a scenario-based panel with cross-functional stakeholders, and some organizations add a final presentation or case study on a mock trial challenge before extending an offer.
Where can I find and apply to clinical operations lead jobs?
You can find and apply to clinical operations lead jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your therapeutic background and experience level, then apply directly to each one that fits.
See All 29 Clinical Operations Lead Jobs
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