Clinical Operations Manager Jobs in St. Louis, MO
Clinical Operations Manager jobs in St. Louis are concentrated in the life sciences and healthcare corridors of Clayton, Midtown, and the emerging Cortex Innovation District, with strong demand from health systems, specialty pharma, and clinical research organizations. Employers hiring right now include BJC HealthCare, Washington University in St. Louis, and SSM Health. See the openings below and apply to the ones that match your experience.
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Showing 5 of 327+ Clinical Operations Manager jobs
- Saint Louis, Missouri
- Nursing Services
- Days
- Full-Time
- 112254
- STL1-R50
- $32.00 – $48.28 / hour (Salary or hourly rate is based on job qualifications and relevant work experience)
Job Description
- The BJC Registerd Nurse Career Ladder differentiates BJC as the place for nurses to work in the greater St. Louis area.
- This is a tool to empower nurses to work at the top of their license and own their career progression.
- The BJC RN Career Ladder promotes professional development, leadership, collaboration, education and service excellence and gives staff the opportunity to continue doing what they do best - caring for patients - while having the opportunity to advance to the next step in their career.
- Moves to higher ladder levels will result in a percentage increase of current pay that aligns with the new job description.
- Benefits include but not limited to Medical, Dental, Vision, 401K with Match, Tuition Assistance
- 7:30-6 PM plus call
- Sign on Bonus up to $7500.00
- 2 yrs ICU, ED, IR or Cath Lab experience
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
Picture yourself working with the most world renowned Interventional Radiologists or Neuro Radiologists in the country, who are using the latest in diagnostic and therapeutic tools to help make life-changing decisions on behalf of patient care.¿The Vascular and Neuro Interventional radiologists of the Mallinckrodt Institute of Radiology Magnetic Resonance Imaging (MIR) at Barnes-Jewish Hospital pioneered, and are responsible for, many radiologic milestones.¿ These two distinct radiological clinical service lines are organized as follows: Interventional Radiology, includes a team of close- knit clinical specialists (Medical Doctors, Registered Nurses, and¿ Radiologic Technologists) who perform highly specialized Vascular and Interventional procedures, including most types of angiographic studies, nonvascular interventions, intra-vascular thrombolysis and central venous catheter placements. Neuroradiology, comprises highly trained Radiologists, Radiologic Technologists and Registered Nurses who work as a team to perform complex procedures such as cerebral angiography, myelography, stent placements and aneurysm coilings and embolizations. The Radiology Department at the Washington University Medical Center is regarded as one of the top five in the United States. It performs over 453,000 diagnostic and interventional imaging procedures annually.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
Job Description
- The BJC Registerd Nurse Career Ladder differentiates BJC as the place for nurses to work in the greater St. Louis area.
- This is a tool to empower nurses to work at the top of their license and own their career progression.
- The BJC RN Career Ladder promotes professional development, leadership, collaboration, education and service excellence and gives staff the opportunity to continue doing what they do best - caring for patients - while having the opportunity to advance to the next step in their career.
- Moves to higher ladder levels will result in a percentage increase of current pay that aligns with the new job description.
- Benefits include but not limited to Medical, Dental, Vision, 401K with Match, Tuition Assistance
- 7:30-6 PM plus call
- Sign on Bonus up to $7500.00
- 2 yrs ICU, ED, IR or Cath Lab experience
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
Picture yourself working with the most world renowned Interventional Radiologists or Neuro Radiologists in the country, who are using the latest in diagnostic and therapeutic tools to help make life-changing decisions on behalf of patient care.¿The Vascular and Neuro Interventional radiologists of the Mallinckrodt Institute of Radiology Magnetic Resonance Imaging (MIR) at Barnes-Jewish Hospital pioneered, and are responsible for, many radiologic milestones.¿ These two distinct radiological clinical service lines are organized as follows: Interventional Radiology, includes a team of close- knit clinical specialists (Medical Doctors, Registered Nurses, and¿ Radiologic Technologists) who perform highly specialized Vascular and Interventional procedures, including most types of angiographic studies, nonvascular interventions, intra-vascular thrombolysis and central venous catheter placements. Neuroradiology, comprises highly trained Radiologists, Radiologic Technologists and Registered Nurses who work as a team to perform complex procedures such as cerebral angiography, myelography, stent placements and aneurysm coilings and embolizations. The Radiology Department at the Washington University Medical Center is regarded as one of the top five in the United States. It performs over 453,000 diagnostic and interventional imaging procedures annually.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
To learn more, go to our Benefits Summary.
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
- Saint Louis, Missouri
- Nursing Services
- Days
- Full-Time
- 112254
- STL1-R50
- $32.00 – $48.28 / hour (Salary or hourly rate is based on job qualifications and relevant work experience)
Job Description
- The BJC Registerd Nurse Career Ladder differentiates BJC as the place for nurses to work in the greater St. Louis area.
- This is a tool to empower nurses to work at the top of their license and own their career progression.
- The BJC RN Career Ladder promotes professional development, leadership, collaboration, education and service excellence and gives staff the opportunity to continue doing what they do best - caring for patients - while having the opportunity to advance to the next step in their career.
- Moves to higher ladder levels will result in a percentage increase of current pay that aligns with the new job description.
- Benefits include but not limited to Medical, Dental, Vision, 401K with Match, Tuition Assistance
- 7:30-6 PM plus call
- Sign on Bonus up to $7500.00
- 2 yrs ICU, ED, IR or Cath Lab experience
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
Picture yourself working with the most world renowned Interventional Radiologists or Neuro Radiologists in the country, who are using the latest in diagnostic and therapeutic tools to help make life-changing decisions on behalf of patient care.¿The Vascular and Neuro Interventional radiologists of the Mallinckrodt Institute of Radiology Magnetic Resonance Imaging (MIR) at Barnes-Jewish Hospital pioneered, and are responsible for, many radiologic milestones.¿ These two distinct radiological clinical service lines are organized as follows: Interventional Radiology, includes a team of close- knit clinical specialists (Medical Doctors, Registered Nurses, and¿ Radiologic Technologists) who perform highly specialized Vascular and Interventional procedures, including most types of angiographic studies, nonvascular interventions, intra-vascular thrombolysis and central venous catheter placements. Neuroradiology, comprises highly trained Radiologists, Radiologic Technologists and Registered Nurses who work as a team to perform complex procedures such as cerebral angiography, myelography, stent placements and aneurysm coilings and embolizations. The Radiology Department at the Washington University Medical Center is regarded as one of the top five in the United States. It performs over 453,000 diagnostic and interventional imaging procedures annually.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
Job Description
- The BJC Registerd Nurse Career Ladder differentiates BJC as the place for nurses to work in the greater St. Louis area.
- This is a tool to empower nurses to work at the top of their license and own their career progression.
- The BJC RN Career Ladder promotes professional development, leadership, collaboration, education and service excellence and gives staff the opportunity to continue doing what they do best - caring for patients - while having the opportunity to advance to the next step in their career.
- Moves to higher ladder levels will result in a percentage increase of current pay that aligns with the new job description.
- Benefits include but not limited to Medical, Dental, Vision, 401K with Match, Tuition Assistance
- 7:30-6 PM plus call
- Sign on Bonus up to $7500.00
- 2 yrs ICU, ED, IR or Cath Lab experience
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
Picture yourself working with the most world renowned Interventional Radiologists or Neuro Radiologists in the country, who are using the latest in diagnostic and therapeutic tools to help make life-changing decisions on behalf of patient care.¿The Vascular and Neuro Interventional radiologists of the Mallinckrodt Institute of Radiology Magnetic Resonance Imaging (MIR) at Barnes-Jewish Hospital pioneered, and are responsible for, many radiologic milestones.¿ These two distinct radiological clinical service lines are organized as follows: Interventional Radiology, includes a team of close- knit clinical specialists (Medical Doctors, Registered Nurses, and¿ Radiologic Technologists) who perform highly specialized Vascular and Interventional procedures, including most types of angiographic studies, nonvascular interventions, intra-vascular thrombolysis and central venous catheter placements. Neuroradiology, comprises highly trained Radiologists, Radiologic Technologists and Registered Nurses who work as a team to perform complex procedures such as cerebral angiography, myelography, stent placements and aneurysm coilings and embolizations. The Radiology Department at the Washington University Medical Center is regarded as one of the top five in the United States. It performs over 453,000 diagnostic and interventional imaging procedures annually.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
To learn more, go to our Benefits Summary.
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
See All 327+ Clinical Operations Manager Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find JobsClinical Operations Manager Job Market in St. Louis
Who's Hiring
- BJC HealthCare144
- Washington University in St. Louis57
- SSM Health38
- Mercy14
- State of Missouri8
Top Industries Hiring
- Healthcare & Medical Services52
- Education44
- Technology & Software2
- Distribution & Wholesale2
- Consulting & Professional Services2
Clinical Operations Manager Jobs in St. Louis: Frequently Asked Questions
How do I get a clinical operations manager job in St. Louis?
Focus your search on St. Louis's dense healthcare and life sciences ecosystem, particularly large health systems anchored in Midtown and Clayton, clinical research organizations in the Cortex Innovation District, and regional specialty pharma and biotech firms. Candidates who can demonstrate cross-functional trial oversight, regulatory compliance experience, and familiarity with multi-site clinical operations stand out in this market. Networking through local hospital systems and research institutions also gives you a real edge here.
Which companies hire clinical operations managers in St. Louis?
St. Louis clinical operations manager roles are posted by BJC HealthCare, Washington University in St. Louis, and SSM Health and others right now, based on current listings on Migrate Mate as of July 2026. St. Louis attracts a mix of major academic medical centers, regional health systems, and mid-size clinical research organizations, all of which hire at multiple levels of clinical operations leadership.
Are there remote clinical operations manager jobs in St. Louis?
Yes, though with limits, since many clinical operations manager responsibilities require on-site presence for trial oversight, staff management, and facility coordination. About 44% of clinical operations manager openings tied to St. Louis are remote or hybrid as of July 2026, with the remote-eligible roles typically covering protocol development, vendor management, and data reporting rather than day-to-day site operations.
How can I get a clinical operations manager job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is moving up from a clinical research coordinator or clinical trial associate role at one of the city's academic medical centers or regional CROs, which regularly hire entry-level staff and promote from within. Building experience with IRB submissions, site monitoring, and GCP compliance in those roles positions you well for a manager-level step. Volunteering with research programs at institutions in the Midtown medical corridor can also open doors.
Which industries hire the most clinical operations managers in St. Louis?
St. Louis clinical operations manager roles concentrate in Healthcare & Medical Services, Education, and Technology & Software, based on current listings on Migrate Mate as of July 2026. St. Louis's long-standing strength in academic medicine and its growing life sciences corridor drive consistent demand across those sectors for experienced clinical operations leadership.
See All 327+ Clinical Operations Manager Jobs in St. Louis
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