Clinical Operations Manager Jobs
Clinical Operations Manager jobs are open across pharmaceuticals, biotechnology, medical devices, and health systems, from mid-level coordinator roles to senior and director-level positions, with specializations in clinical trials, regulatory affairs, and site management. Find a role that fits from the openings below and apply directly.
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Showing 5 of 665+ Clinical Operations Manager jobs
Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology.
- Collaborate with project teams to implement study startup activities, including communication planning, logistics, development of study documentation, and data configuration.
- Instill confidence with clients on study operations through start up, maintenance and close out activities.
- Act as the primary point of contact for clinical sites, ensuring smooth operations and clear communication.
- Provide training to research sites on the use of Beacon's devices and study protocols, ensuring proper device usage and data collection.
- Monitor project progress, ensuring adherence to timelines, protocols, and quality standards.
- Maintain compliance with Good Clinical Practice (GCP), International Conference on Harmonization (ICH) guidelines, and regulatory standards.
- Foster a culture of quality within the ClinOps and Scientific teams by coaching peers on GCP requirements, documentation discipline, versioning, and complaint management.
- Address operational issues promptly, escalating through tools like Zendesk and Asana for resolution.
- Provide actionable feedback from research sites to inform improvements in devices and workflows.
- Experience in clinical project management or clinical operations roles.
- Strong organizational and project management skills, with the ability to manage multiple responsibilities effectively.
- Excellent written and verbal communication skills in English; additional languages are a bonus.
- A proactive mindset with the ability to identify priorities and anticipate challenges.
- Meticulous attention to detail, ensuring accuracy in data collection and reporting.
- Ability to work in a fast paced environment with multiple priorities.
- Familiarity with GCP, ICH guidelines, and clinical research regulatory requirements.
- Knowledge of decentralized data collection, compliance and oversight while showing empathy for both patients and sites.
- A desire to learn more about analytics, statistics, machine learning, and clinical trials.
Beacon Biosignals is transforming precision medicine for the brain, from clinical development to clinical care. For Life Sciences partners, we offer the leading at-home EEG platform for clinical development of novel therapeutics for neurological, psychiatric, and sleep disorders. Our Diagnostics business is building the most comprehensive at-home platform for precision diagnostics, combining EEG and cardiopulmonary signals to deliver reimbursable assessments for sleep and central nervous system disorders. Together, we're changing the way patients are diagnosed and treated for any disorder that affects brain physiology.
- Collaborate with project teams to implement study startup activities, including communication planning, logistics, development of study documentation, and data configuration.
- Instill confidence with clients on study operations through start up, maintenance and close out activities.
- Act as the primary point of contact for clinical sites, ensuring smooth operations and clear communication.
- Provide training to research sites on the use of Beacon's devices and study protocols, ensuring proper device usage and data collection.
- Monitor project progress, ensuring adherence to timelines, protocols, and quality standards.
- Maintain compliance with Good Clinical Practice (GCP), International Conference on Harmonization (ICH) guidelines, and regulatory standards.
- Foster a culture of quality within the ClinOps and Scientific teams by coaching peers on GCP requirements, documentation discipline, versioning, and complaint management.
- Address operational issues promptly, escalating through tools like Zendesk and Asana for resolution.
- Provide actionable feedback from research sites to inform improvements in devices and workflows.
- Experience in clinical project management or clinical operations roles.
- Strong organizational and project management skills, with the ability to manage multiple responsibilities effectively.
- Excellent written and verbal communication skills in English; additional languages are a bonus.
- A proactive mindset with the ability to identify priorities and anticipate challenges.
- Meticulous attention to detail, ensuring accuracy in data collection and reporting.
- Ability to work in a fast paced environment with multiple priorities.
- Familiarity with GCP, ICH guidelines, and clinical research regulatory requirements.
- Knowledge of decentralized data collection, compliance and oversight while showing empathy for both patients and sites.
- A desire to learn more about analytics, statistics, machine learning, and clinical trials.
Clinical Operations Manager Jobs by Experience Level
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Find JobsClinical Operations Manager Job Market
Who's Hiring
- University of Miami24
- KBR14
- Indiana University Health11
- Revolution Medicines9
- Providence8
Top Industries Hiring
- Healthcare & Medical Services84
- Biotechnology & Pharmaceuticals35
- Education29
- Science & Research13
- Technology & Software7
What Employers Look For
The qualifications that appear most often in clinical operations manager jobs.
- Bachelor's degree in life sciences, nursing, or a related clinical field
- Minimum five years of clinical trial or clinical operations experience
- Proficiency with clinical trial management systems such as Veeva or Medidata
- Strong working knowledge of ICH-GCP guidelines and FDA regulations
- Experience managing CROs, vendors, or multi-site study teams
- Project Management Professional or equivalent certification preferred
Tips for Your Clinical Operations Manager Job Search
Tailor your resume to trial phase
Hiring managers scan for Phase I through Phase IV experience. List the specific trial phases you've managed, the therapeutic areas covered, and the size of the sites or patient populations you oversaw. Vague operations experience won't stand out.
Lead with protocol deviation metrics
Clinical operations roles live and die by data quality and compliance. Quantify your deviation rates, audit outcomes, or inspection-readiness scores on your resume. Concrete numbers from real studies tell interviewers far more than a list of responsibilities.
Filter openings by sponsor versus CRO
Sponsor-side roles and CRO roles require different emphases: sponsors want strategic oversight, CROs want throughput and client management. Decide which environment fits your background before applying so your cover letter speaks directly to that model.
Apply early to roles that fit
Migrate Mate lists clinical operations manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare scenario answers on risk escalation
Interviewers routinely ask how you handled a site that fell behind enrollment or triggered a protocol deviation. Prepare two or three specific examples where you identified a risk early, escalated appropriately, and documented the resolution for the sponsor or IRB.
Negotiate start date around study timelines
If you're mid-study at your current role, a hard start date can cost you the offer. When discussing timing, name the milestone you're completing and offer a firm date. Sponsors appreciate candidates who treat protocol continuity as a professional obligation.
Clinical Operations Manager Jobs: Frequently Asked Questions
Which companies are hiring the most clinical operations managers?
The companies hiring the most clinical operations managers right now include University of Miami, KBR, and Indiana University Health, with the largest share of openings in California, Massachusetts, and Florida, based on current listings on Migrate Mate as of August 2026. Demand is concentrated in large pharmaceutical sponsors, contract research organizations, and integrated health systems running decentralized or hybrid trials.
How many clinical operations manager jobs are remote?
About 42% of clinical operations manager openings are fully remote or hybrid as of August 2026, reflecting the shift toward decentralized trial models. Roles focused on vendor oversight, data management coordination, and regulatory submissions tend to offer the most remote flexibility, while positions requiring hands-on site monitoring or lab oversight more often require on-site presence.
How do you become a clinical operations manager?
Most clinical operations managers start as clinical research associates or trial coordinators, building site management and GCP compliance experience across multiple studies. From there, moving into a lead CRA or senior coordinator role adds the oversight and vendor management skills employers expect. A relevant degree in life sciences or nursing is the typical educational foundation, and many candidates add a project management certification to strengthen their application for manager-level roles.
Can you get a clinical operations manager role with limited experience?
It's possible if you can demonstrate deep hands-on experience in a closely related role. CRAs with strong audit and protocol deviation records, regulatory affairs coordinators, or clinical data managers who have led cross-functional workstreams often move into operations manager roles without a traditional manager title in their history. Targeting smaller sponsors or early-stage biotechs can also lower the experience bar compared to large pharmaceutical companies.
What does the clinical operations manager interview process look like?
The process typically opens with a recruiter screen focused on therapeutic area experience and systems knowledge, followed by a panel interview with clinical operations leadership and cross-functional partners such as data management or regulatory affairs. Candidates are usually asked to walk through a past study from protocol kick-off to close-out, with detailed questions on how they handled site issues, vendor performance, and inspection readiness. A final round may include a case study or take-home scenario.
Where can I find and apply to clinical operations manager jobs?
You can find and apply to clinical operations manager jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your background and apply directly to each listing. Openings are updated regularly, so checking back frequently gives you access to newly posted positions before they fill.
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