Clinical Operations Manager Jobs
Clinical Operations Manager jobs are open across pharmaceuticals, biotechnology, medical devices, and health systems, from mid-level coordinator roles to senior and director-level positions, with specializations in clinical trials, regulatory affairs, and site management. Find a role that fits from the openings below and apply directly.
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INTRODUCTION
At UC Health, we're proud to have the best and brightest teams and clinicians collaborating toward our common purpose: to advance healing and reduce suffering.
As the region's adult academic health system, we strive for innovation and provide world-class care for not only our community, but patients from all over the world. Join our team and you'll be able to develop your skills, grow your career, build relationships with your peers and patients, and help us be a source of hope for our friends and neighbors.
UC Health is an EEO employer.
ROLE AND RESPONSIBILITIES
Responsible for overall management of practice sites, enforcing policies and procedures, operations efficiency, budget management, revenue maximization and customer service expectations. Troubleshoot daily flow and manage activities of staff to include both clinical and clerical support personnel.
Clinical Operations: Oversee daily activities to assure patient safety and appropriate cost effective care delivery. Work closely with physicians to meet their needs and to improve efficiency in the practice. Enforce department and UCP (UC Physicians) policy and procedure. Implement and monitor work flows within the practices to identify and evaluate improvement opportunities that will enhance the practice’s ability to meet and excel UCP ambulatory clinical benchmarks. Coordinate department activities to assure unified approach to quality care delivery. Participate and collaborate with other managers within UC Health for monthly meetings and clinical initiatives. Actively participate as a member of appropriate UCP/HC Health Committees as assigned by senior management.
Education: Precept and mentor new employees. Provide ongoing education and competency evaluation/review. Ensure new employee departmental orientation is completed within 90 days of hire.
Personnel Management: Provide guidance, psychosocial support, clinical precepting and mentoring of staff. Prepare and present performance appraisals of staff; initiate corrective action and assist in conflict resolution to maintain personal and professional growth of staff. Communicate with Human Resources prior to verbal reprimands, written warnings and/or terminations. Participate in recruitment, hiring, retention, payroll and benefit issues. Facilitate routine and recurring staff meetings.
Marketing: Act as a liaison for internal and external resources to assure a unified approach to patient care delivery. Partner with the marketing department for office signage, marketing template, and web site changes when needed.
Quality Improvement (QI): Develop QI projects and collect and analyze data to validate effectiveness and appropriateness. (Projects include departmental programs; productivity, clinical practice, equipment, policy and procedure, infection control; and multidisciplinary programs: policy and procedures, clinical practice standards, etc.) Review monthly commentator and devise implement a plan to improve access, internal quality and clinical metrics, and patient experience for patients.
Resource Management: Provide assistance in preparation of the budget, charging/billing for department, pre-certification, registration accuracy, open and pending encounters, and other revenue cycle opportunities, as assigned by management. Manage assigned areas of responsibility within budget level of expense. Evaluate supplies, capital equipment and assure proper inventory is maintained. Coordinate equipment repairs and ordering of rental equipment. Conduct research on equipment, supplies, and clinical care to assure excellence. Assist in personnel scheduling to optimize staffing resources. Develop productivity standards to appropriately allocate staff and effectively manage personnel budget.
Regulatory Compliance: Work with physicians and staff to assure compliance with applicable regulatory agency requirements (i.e. Joint Commission, OSHA, ODH, and Billing).
Environment: While performing the duties of this job, the employee is regularly required to communicate professionally in person, over the telephone, through e-mail and other electronic means, move about the office, handle various types of media and equipment, and visually or otherwise identify, observe, and assess.
Other: Perform all other duties as requested by management.
MINIMUM QUALIFICATIONS
Bachelor's Degree-General Studies or Health Care Related. For employees working in UCMC Psychiatric Services, NCI-APS (Nonviolent Crisis Intervention with Advanced Physical Skills) Certification must be obtained within 90 days of hire. Minimum Required: 3 - 5 Years equivalent experience. Preferred: 6 - 10 Years equivalent experience.
INTRODUCTION
At UC Health, we're proud to have the best and brightest teams and clinicians collaborating toward our common purpose: to advance healing and reduce suffering.
As the region's adult academic health system, we strive for innovation and provide world-class care for not only our community, but patients from all over the world. Join our team and you'll be able to develop your skills, grow your career, build relationships with your peers and patients, and help us be a source of hope for our friends and neighbors.
UC Health is an EEO employer.
ROLE AND RESPONSIBILITIES
Responsible for overall management of practice sites, enforcing policies and procedures, operations efficiency, budget management, revenue maximization and customer service expectations. Troubleshoot daily flow and manage activities of staff to include both clinical and clerical support personnel.
Clinical Operations: Oversee daily activities to assure patient safety and appropriate cost effective care delivery. Work closely with physicians to meet their needs and to improve efficiency in the practice. Enforce department and UCP (UC Physicians) policy and procedure. Implement and monitor work flows within the practices to identify and evaluate improvement opportunities that will enhance the practice’s ability to meet and excel UCP ambulatory clinical benchmarks. Coordinate department activities to assure unified approach to quality care delivery. Participate and collaborate with other managers within UC Health for monthly meetings and clinical initiatives. Actively participate as a member of appropriate UCP/HC Health Committees as assigned by senior management.
Education: Precept and mentor new employees. Provide ongoing education and competency evaluation/review. Ensure new employee departmental orientation is completed within 90 days of hire.
Personnel Management: Provide guidance, psychosocial support, clinical precepting and mentoring of staff. Prepare and present performance appraisals of staff; initiate corrective action and assist in conflict resolution to maintain personal and professional growth of staff. Communicate with Human Resources prior to verbal reprimands, written warnings and/or terminations. Participate in recruitment, hiring, retention, payroll and benefit issues. Facilitate routine and recurring staff meetings.
Marketing: Act as a liaison for internal and external resources to assure a unified approach to patient care delivery. Partner with the marketing department for office signage, marketing template, and web site changes when needed.
Quality Improvement (QI): Develop QI projects and collect and analyze data to validate effectiveness and appropriateness. (Projects include departmental programs; productivity, clinical practice, equipment, policy and procedure, infection control; and multidisciplinary programs: policy and procedures, clinical practice standards, etc.) Review monthly commentator and devise implement a plan to improve access, internal quality and clinical metrics, and patient experience for patients.
Resource Management: Provide assistance in preparation of the budget, charging/billing for department, pre-certification, registration accuracy, open and pending encounters, and other revenue cycle opportunities, as assigned by management. Manage assigned areas of responsibility within budget level of expense. Evaluate supplies, capital equipment and assure proper inventory is maintained. Coordinate equipment repairs and ordering of rental equipment. Conduct research on equipment, supplies, and clinical care to assure excellence. Assist in personnel scheduling to optimize staffing resources. Develop productivity standards to appropriately allocate staff and effectively manage personnel budget.
Regulatory Compliance: Work with physicians and staff to assure compliance with applicable regulatory agency requirements (i.e. Joint Commission, OSHA, ODH, and Billing).
Environment: While performing the duties of this job, the employee is regularly required to communicate professionally in person, over the telephone, through e-mail and other electronic means, move about the office, handle various types of media and equipment, and visually or otherwise identify, observe, and assess.
Other: Perform all other duties as requested by management.
MINIMUM QUALIFICATIONS
Bachelor's Degree-General Studies or Health Care Related. For employees working in UCMC Psychiatric Services, NCI-APS (Nonviolent Crisis Intervention with Advanced Physical Skills) Certification must be obtained within 90 days of hire. Minimum Required: 3 - 5 Years equivalent experience. Preferred: 6 - 10 Years equivalent experience.
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Find JobsClinical Operations Manager Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- Indiana University Health8
- Revolution Medicines7
- IQVIA4
- ALPHATEC SPINE3
- The Queen's Medical Center3
Top Industries Hiring
- Healthcare & Medical Services43
- Biotechnology & Pharmaceuticals29
- Consulting & Professional Services9
- Education9
- Medical Devices6
What Employers Look For
The qualifications that appear most often in clinical operations manager jobs.
- Bachelor's degree in life sciences, nursing, or a related clinical field
- Minimum five years of clinical trial or clinical operations experience
- Proficiency with clinical trial management systems such as Veeva or Medidata
- Strong working knowledge of ICH-GCP guidelines and FDA regulations
- Experience managing CROs, vendors, or multi-site study teams
- Project Management Professional or equivalent certification preferred
Tips for Your Clinical Operations Manager Job Search
Tailor your resume to trial phase
Hiring managers scan for Phase I through Phase IV experience. List the specific trial phases you've managed, the therapeutic areas covered, and the size of the sites or patient populations you oversaw. Vague operations experience won't stand out.
Lead with protocol deviation metrics
Clinical operations roles live and die by data quality and compliance. Quantify your deviation rates, audit outcomes, or inspection-readiness scores on your resume. Concrete numbers from real studies tell interviewers far more than a list of responsibilities.
Filter openings by sponsor versus CRO
Sponsor-side roles and CRO roles require different emphases: sponsors want strategic oversight, CROs want throughput and client management. Decide which environment fits your background before applying so your cover letter speaks directly to that model.
Apply early to roles that fit
Migrate Mate lists clinical operations manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare scenario answers on risk escalation
Interviewers routinely ask how you handled a site that fell behind enrollment or triggered a protocol deviation. Prepare two or three specific examples where you identified a risk early, escalated appropriately, and documented the resolution for the sponsor or IRB.
Negotiate start date around study timelines
If you're mid-study at your current role, a hard start date can cost you the offer. When discussing timing, name the milestone you're completing and offer a firm date. Sponsors appreciate candidates who treat protocol continuity as a professional obligation.
Clinical Operations Manager Jobs: Frequently Asked Questions
Which companies are hiring the most clinical operations managers?
The companies hiring the most clinical operations managers right now include Indiana University Health, Revolution Medicines, and IQVIA, with the largest share of openings in California, Indiana, and Massachusetts, based on current listings on Migrate Mate as of June 2026. Demand is concentrated in large pharmaceutical sponsors, contract research organizations, and integrated health systems running decentralized or hybrid trials.
How many clinical operations manager jobs are remote?
About 19% of clinical operations manager openings are fully remote or hybrid as of June 2026, reflecting the shift toward decentralized trial models. Roles focused on vendor oversight, data management coordination, and regulatory submissions tend to offer the most remote flexibility, while positions requiring hands-on site monitoring or lab oversight more often require on-site presence.
How do you become a clinical operations manager?
Most clinical operations managers start as clinical research associates or trial coordinators, building site management and GCP compliance experience across multiple studies. From there, moving into a lead CRA or senior coordinator role adds the oversight and vendor management skills employers expect. A relevant degree in life sciences or nursing is the typical educational foundation, and many candidates add a project management certification to strengthen their application for manager-level roles.
Can you get a clinical operations manager role with limited experience?
It's possible if you can demonstrate deep hands-on experience in a closely related role. CRAs with strong audit and protocol deviation records, regulatory affairs coordinators, or clinical data managers who have led cross-functional workstreams often move into operations manager roles without a traditional manager title in their history. Targeting smaller sponsors or early-stage biotechs can also lower the experience bar compared to large pharmaceutical companies.
What does the clinical operations manager interview process look like?
The process typically opens with a recruiter screen focused on therapeutic area experience and systems knowledge, followed by a panel interview with clinical operations leadership and cross-functional partners such as data management or regulatory affairs. Candidates are usually asked to walk through a past study from protocol kick-off to close-out, with detailed questions on how they handled site issues, vendor performance, and inspection readiness. A final round may include a case study or take-home scenario.
Where can I find and apply to clinical operations manager jobs?
You can find and apply to clinical operations manager jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your background and apply directly to each listing. Openings are updated regularly, so checking back frequently gives you access to newly posted positions before they fill.
See All 103+ Clinical Operations Manager Jobs
Jump back to the full list of openings and apply to any clinical operations manager role that fits.
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