Senior Level Clinical Operations Manager Jobs
Senior level clinical operations manager jobs place experienced professionals in charge of clinical program strategy, cross-functional oversight, and the operational teams that deliver trial or care outcomes. Hiring is concentrated across Technology & Software, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, with 27% of openings offering remote or hybrid arrangements, and employers like Amazon, Revolution Medicines, and Intuit hiring at this level now.
Find JobsOverview
Showing 5 of 251+ Senior Level Clinical Operations Manager jobs
Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.
Discover what your 25,000 future colleagues already know:
Why Syneos Health
- We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
- We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
- We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.
Job Responsibilities
At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range:
$134,400.00 - $255,400.00The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.
Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
http://www.syneoshealth.com
Additional Information
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.
Discover what your 25,000 future colleagues already know:
Why Syneos Health
- We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
- We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
- We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.
Job Responsibilities
At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range:
$134,400.00 - $255,400.00The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.
Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
http://www.syneoshealth.com
Additional Information
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
See All 251+ Senior Level Clinical Operations Manager Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsSenior Level Clinical Operations Manager Job Market
Who's Hiring
- Amazon13
- Revolution Medicines9
- Intuit6
- Amazon Web Services6
- Apple5
Top Industries Hiring
- Technology & Software46
- Healthcare & Medical Services37
- Biotechnology & Pharmaceuticals35
- Retail17
- Education14
Senior Level Clinical Operations Manager Jobs: Frequently Asked Questions
How do I get a senior level clinical operations manager job?
Employers at this level look for candidates who have owned complex clinical programs end to end, not just managed tasks within them. Demonstrating that you have led cross-functional teams, resolved protocol deviations, and made decisions that kept trials on time and on budget will set you apart. Experience mentoring junior staff and presenting to sponsors or leadership strengthens a senior-level candidacy considerably.
Which companies hire senior level clinical operations managers?
Companies hiring senior level clinical operations managers right now include Amazon, Revolution Medicines, and Intuit, based on current listings on Migrate Mate as of July 2026. Hiring at this level is driven by contract research organizations, pharmaceutical and biotech companies, and large health systems that need experienced operators to lead multi-site or multi-study programs.
Are there remote senior level clinical operations manager jobs?
Yes, though availability depends on the employer and program type. About 27% of senior level clinical operations manager openings are remote or hybrid as of July 2026, reflecting broader flexibility in how clinical programs are managed. Roles tied to active site oversight or team leadership often require some on-site presence, while program strategy and vendor management functions more commonly support remote arrangements.
What makes a clinical operations manager role senior level?
Senior level roles are defined by scope and ownership rather than task execution. At this stage, you are accountable for full program or portfolio performance, setting operational standards, and making judgment calls on resourcing, risk, and escalation. You are also expected to mentor junior managers, lead cross-functional initiatives, and serve as the primary operational point of contact for sponsors, leadership, or regulatory teams.
Which industries hire the most senior level clinical operations managers?
Senior level clinical operations manager roles concentrate in Technology & Software, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of July 2026. These sectors drive hiring at this level because they run the largest volumes of clinical trials, regulatory submissions, or care delivery programs, creating ongoing demand for experienced professionals who can lead operations at scale.