Remote Clinical Operations Manager Jobs
Remote Clinical Operations Manager jobs are in active demand across the U.S., with remote-first firms and distributed clinical teams posting openings in pharmaceutical, biotech, contract research, and health technology sectors. Employers hiring remotely right now include Wexford Health Sources, Talkiatry, and Medsien. Scan the live roles below and apply to whichever ones fit.
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Director of Clinical Operations - Population Health RN
Vigilance Health
Remote | Full-Time
You've Done This Work Before. Now Do It At Scale.
You know what it takes to build, mobilize, and lead a remote care management team to excellence. You know what it takes to reach important industry metrics and compliance measures. You understand how to successfully engage and activate patients and how to coach your team of care managers to move the needle on patient health outcomes. You model and create a culture of mutual respect and collaboration. You've sat in rooms with FQHCs, IPAs, and payers and have spoken their language fluently.
Now imagine doing that with the full backing of an organization whose entire mission is built around the delivery of quality population care management — and where your work directly shapes the clinical programs that serve thousands of patients across diverse communities. That's what we're offering and you are who we’re looking for.
Who We Are
Vigilance Health partners with FQHCs, ACOs, IPAs, and payers to deliver Population Health and Care Management services that effect real change in people’s lives. We provide Chronic Care Management (CCM), Advanced Primary Care Management (APCM), Remote Patient Monitoring (RPM), and Behavioral Health Integration (BHI) programs — and we measure success the way our partners do: quality metrics, patient engagement, and improved health outcomes that show up in data.
Our purpose is simple, and we mean it: Change People's Lives — no matter their circumstances.
The Role
As our Clinical Operations Leader, you'll be the clinical engine behind our care management programs. This is a leadership role with real ownership — you'll build and coach the care management team, design and refine the clinical workflows they follow, and hold the clinical bar high across every service line we run.
You'll be working closely with our partners, most of whom are laser-focused on ACO quality measures and patient engagement. When they ask why HEDIS rates are moving or why patients aren't scheduling follow-ups, you'll be the one with answers — and a plan.
This role is remote, and you'll be leading a remote team, so your ability to build culture, accountability, and clinical consistency across distance is critical.
What You'll Own
Team Leadership
You'll recruit, onboard, coach, and develop a team of care managers. You set the standard for what great care management looks like and hold the team to it — with support, not just expectations.
Clinical Workflow Design
You'll build and continuously improve the clinical workflows that drive better outcomes. That means protocols that are practical, documented, and actually followed — not binders that collect dust.
ACO Quality & Patient Engagement Performance
Our partners live and die by their quality metrics. You'll monitor performance across ACO quality measures, identify where the gaps are, and lead the interventions that close them. Patient engagement is core to everything — including call answer rates, appointment scheduling rates, and no-show reduction. You'll understand why those numbers look the way they do and know what levers to pull.
Partner Collaboration
You'll be a trusted clinical voice for our partner sites — joining meetings, co-managing escalations, and making sure the clinical work we do is tightly aligned with what partners need to succeed with their payers and regulatory bodies.
Clinical Oversight Across Programs
Chronic Care Management, APCM, BHI, RPM — you'll ensure clinical standards, regulatory alignment, and documentation quality.
What Good Looks Like in 12 Months
-
Your care managers are hitting productivity targets and delivering high-quality, personalized care.
- ACO quality measure performance is trending up across partner panels.
Patient engagement rates — calls answered, appointments kept, reduction in no-
shows — are measurably improving.
- Clinical workflows are standardized, followed, and audit-ready.
- Partners view you as an extension of their clinical leadership team.
Leadership has clear, real-time visibility into performance, risk analysis, population analysis, and opportunity.
What You Bring
Experience That Matters Most
- Active RN license (BSN required; MSN a plus)
Experience working in or directly with FQHCs, ACOs, IPAs, or payers- Extensive familiarity with ACO quality measures (HEDIS, UDS, or equivalent)
Prior leadership of a remote care management program — you've managed remote
clinical staff and know how to build teamwork and accountability at a distance
5+ years of clinical experience, with meaningful time in population health or care
management
Nice to Have
- CCM, CPHQ, or population health certification
- Behavioral Health Integration (BHI) experience
- Experience launching or scaling new care management service lines
The Kind of Person Who Thrives Here
You're a self-starter and solution-focused. You can zoom out and think large-scale strategy and zoom in to, for example, coach a care manager on a specific patient interaction. You communicate clearly with clinical teams, operations leads, and external partners without losing anything in translation. When the data doesn't look right, you dig in.
Why Vigilance Health
-
Direct impact — your work shapes outcomes for real patients in real communities
- Leadership with latitude — we give you room to build programs the right way
- Mission-aligned partners — we work with organizations that care as much as we do
- Growth-oriented— we are scaling and adding partners who are driven by progress and excellence
- A team that has your back — we are collaborative and invested in each other's success
If you've been looking for a role where your population health expertise drives the clinical direction of a clinical team and an organization — this is it. We look forward to hearing from you.
Apply today. Let's change lives together.
Vigilance Health is an equal opportunity employer committed to building a diverse, inclusive team.
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Who's Hiring



Top Industries Hiring
- Technology & Software
What Employers Look For
The qualifications that appear most often in remote clinical operations manager jobs.
- Bachelor's degree in life sciences, nursing, or a related clinical field
- Minimum five years of clinical trial or clinical operations experience
- Proficiency with clinical trial management systems such as Veeva or Medidata
- Strong working knowledge of ICH-GCP guidelines and FDA regulations
- Experience managing CROs, vendors, or multi-site study teams
- Project Management Professional or equivalent certification preferred
Tips for Your Remote Clinical Operations Manager Job Search
Apply early to remote roles that fit
Migrate Mate lists remote clinical operations manager openings from across the U.S. in one place, so you can find roles that match your background and apply directly without sorting through unrelated postings.
Show your async coordination experience up front
Remote clinical operations managers run study timelines across time zones without in-person check-ins. Describe specific projects where you coordinated site activations, vendor deliverables, or protocol deviations entirely through written updates and digital tools, not just meetings.
Name the remote trial management tools you know
Remote hiring managers screen for familiarity with clinical trial management systems, electronic data capture platforms, and regulatory submission tools. Call out the systems you've used, your depth of use, and whether you've trained others on them.
Prepare for remote interview scenarios on independent judgment
Remote clinical operations manager interviews consistently probe how you handle site issues, protocol deviations, or vendor delays without escalating immediately. Walk through a real situation where you diagnosed and resolved a trial operations problem on your own, then communicated the outcome clearly.
Remote Clinical Operations Manager Jobs: Frequently Asked Questions
How do I get a remote clinical operations manager job?
Target remote-first biotech, pharma, and contract research organizations, since those sectors run distributed clinical teams most consistently. Remote employers screen clinical operations managers hard on written communication, async coordination, and the ability to manage trial timelines without in-person oversight. Candidates who can point to specific cross-functional projects they managed independently, and who show fluency with trial management and regulatory documentation tools, stand out immediately.
Which companies hire remote clinical operations managers?
Companies hiring remote clinical operations managers right now include Wexford Health Sources, Talkiatry, and Medsien, based on current remote listings on Migrate Mate as of November 2026. Remote-first contract research organizations, digital health companies, and distributed biotech teams account for the largest share of these openings.
Can you get a remote clinical operations manager job with no experience?
Yes, but remote entry-level roles are harder to land because you're expected to work independently from day one without in-person mentorship. Smaller remote-first CROs and digital health startups are the most open to earlier-career candidates. Showing completed coursework in clinical research, hands-on exposure through internships or coordinator roles, and clear written communication skills can substitute for years of direct experience.
Do you need a degree for remote clinical operations manager jobs?
Usually, but the field matters more than the credential itself. Most remote employers expect a bachelor's degree in a life sciences, nursing, or health-related discipline as a baseline. What carries equal or greater weight is demonstrated experience managing clinical trials, regulatory knowledge, and the ability to keep distributed study teams aligned, which candidates can show through a strong work history even without an advanced degree.
Which industries hire the most remote clinical operations managers?
Remote clinical operations manager roles concentrate in Technology & Software, based on current remote listings on Migrate Mate as of November 2026. Those sectors run multi-site studies and distributed clinical teams by design, which makes remote clinical operations management a natural fit rather than an exception.
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