Senior Level Clinical Operations Specialist Jobs

Senior level clinical operations specialist jobs place experienced professionals in charge of trial oversight, cross-functional team leadership, and the operational decisions that keep complex studies on time and compliant. The mix is predominantly remote and hybrid, with openings concentrated in Biotechnology & Pharmaceuticals, Education, and Healthcare & Medical Services, and employers like Revolution Medicines, Revolution Medicines, and University of Florida hiring at this level now.

Find Jobs

Overview

Open roles357+
Top stateCalifornia
Top employerRevolution Medicines
Top cityRedwood City, CA
Work type79% On-site
Top industryBiotechnology

Showing 5 of 357+ Senior Level Clinical Operations Specialist jobs

Clinical Assistant Professor
We won't show you this job again
New 1h ago
Clinical Assistant Professor
The University of Michigan
Ann Arbor, Michigan
Nursing
Medical Specialists
Healthcare Administration
Clinical Support
Physicians
Surgeons
On-Site
Doctorate
10,000+

Have you applied for this role?

Sr. Program Manager, Business Ops
We won't show you this job again
New 9h ago
Sr. Program Manager, Business Ops
Avalara
Remote
AI (Artificial Intelligence)
Product Management
Technical Product & Program Management
Remote (US)
Bachelor's degree in business
1,001-5,000

Have you applied for this role?

Sr. Director, Clinical Supply
We won't show you this job again
New 12h ago
Sr. Director, Clinical Supply
Glaukos
Aliso Viejo, California
Project & Program Management
Procurement & Supply Chain
Partnerships & Business Development
Compliance & Legal
Human Resources
Project Management
Supply Chain
Business Development
Compliance & Risk
$210k - $262k/yr
On-Site
Bachelor's
51-200

Have you applied for this role?

Clinical Science Lead
We won't show you this job again
New 15h ago
Clinical Science Lead
Takeda Pharmaceuticals
Boston, Massachusetts
Biotech & Life Sciences
Clinical Trials
Research & Academia
$177k - $278k/yr
10,000+

Have you applied for this role?

Anatomic and Clinical Pathologist
We won't show you this job again
New 20h ago
Anatomic and Clinical Pathologist
Optum
Houston, Texas
Medical Specialists
Healthcare Administration
Allied Health
Physicians
Laboratory Science
$325k - $544k/yr
On-Site
Doctorate
10,000+

Have you applied for this role?

See All 357+ Senior Level Clinical Operations Specialist Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs

Senior Level Clinical Operations Specialist Job Market

Who's Hiring

  • Revolution Medicines54
  • University of Florida18
  • Jobot13
  • University Of Washington12

Top Industries Hiring

  • Biotechnology & Pharmaceuticals107
  • Education77
  • Healthcare & Medical Services76
  • Science & Research18
  • Staffing & Recruiting14

Senior Level Clinical Operations Specialist Jobs: Frequently Asked Questions

How do I get a senior level clinical operations specialist job?

Employers at this level look for demonstrated ownership of full study lifecycles, not just task execution. Highlight experience leading monitoring strategies, managing CROs or site networks, and resolving protocol deviations independently. Cross-functional leadership, regulatory submission support, and a history of mentoring junior staff all signal readiness for a senior role. Tailoring your resume to show scope and accountability, rather than activity, gives you the clearest edge.

Which companies hire senior level clinical operations specialists?

Companies hiring senior level clinical operations specialists right now include Revolution Medicines, Revolution Medicines, and University of Florida, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes primarily from large pharmaceutical and biotech sponsors, full-service CROs, and medical device firms managing late-phase or post-market studies.

Are there remote senior level clinical operations specialist jobs?

Yes, remote and hybrid availability is strong at this level. About 21% of senior level clinical operations specialist openings are remote or hybrid as of November 2026, reflecting how sponsors and CROs have restructured oversight roles around centralized monitoring and electronic data systems. On-site roles do exist, typically tied to site-based or early-phase programs.

What makes a clinical operations specialist role senior level?

Senior level roles are defined by ownership and scope rather than task completion. Expectations include leading study teams or vendor relationships independently, setting monitoring and risk management strategy, contributing to SOPs or process improvements, and mentoring coordinators or junior specialists. The work shifts from executing directives to making operational decisions and being accountable for study outcomes across multiple protocols or therapeutic areas.

Which industries hire the most senior level clinical operations specialists?

Senior level clinical operations specialist roles concentrate in Biotechnology & Pharmaceuticals, Education, and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they run the largest and most complex clinical programs, requiring experienced professionals who can manage regulatory risk and coordinate across global site networks.