Clinical Program Manager Jobs in Boston, MA
Clinical Program Manager jobs in Boston are concentrated in the Longwood Medical Area, Seaport, and downtown Financial District, with strong demand across academic medical centers, biopharma, and health-tech. Employers actively hiring include Tufts Medical Center, Boston Medical Center, and Boston University. See the openings below and apply to the ones that match your experience.
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Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
recruiting a full-time Clinical Research Program Manager to join its multidisciplinary team. The
program manager will work closely with the principal investigator in collaboration with a
diverse group of researchers (oncologists, palliative care clinicians, psychiatrists, psychologists)
to oversee the day-to-day administration of program activities. The program manager will
contribute to the development of study protocols and procedures, and the preparation and
submission of research manuscripts, abstracts, and grant applications. The program manager
will be responsible for hiring and onboarding new staff as well as maintaining a working
knowledge of clinical research conduct to support study-related activities and initiatives across
the program locally and nationally.
Qualifications
- Minimum of 2 years of management experience required
- Collaborate with the principal investigator to oversee all laboratory projects
- Work closely with the principal investigator on grant submissions, including summarizing
developing templates for required documents, and collecting required documentation
from investigators and study sites
- Assist with manuscript preparation for peer-reviewed journals, including performing
submission
- Assist with abstract and presentation submissions for local, regional, national, and
- Assist with writing protocols for CARE studies, including Institutional Review Board
maintaining study amendments and continuing reviews
- Collaborate with the principal investigator to develop standard operating procedures and
- Oversee all Institutional Review Board communications regarding projects
- Monitor progression of clinical trials against project milestones
- Oversee all study procedures, compliance, and communication with all collaborating
- Oversee all data collection in collaboration with clinical research coordinators for accuracy
- Oversee internal and external audits and coordinate all processes with Data Safety and Monitoring Boards for all clinical trials
- Act as the point of contact for CARE members to provide direction and guidance regarding
- Maintain centralized training records for all research staff
- Maintain and update CARE email distribution lists and manage the CARE meeting
- Work with the Development Office to support activities for CARE donors, including Patient
- Oversee program website to ensure content is current and accurate; manage CARE study
Management responsibilities will include the following:
- Manage hiring process for new clinical research coordinators and project manager positions
- Onboard and oversee new research staff, interns, and volunteers
- Serve as liaison regarding issues related to human resources
- Assess computer equipment acquisition and training needs
- Manage CARE research space
- Oversee system access and support the use of research technology systems
- Perform other managerial and administrative responsibilities as assigned to support the
Additional Job Details (if applicable)
- Master’s degree or PhD preferred
- Minimum of 5 years of research experience preferred
Remote Type
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At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement:
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
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Find Clinical Program Manager JobsClinical Program Manager Job Market in Boston
Who's Hiring
- Tufts Medical Center17

- Boston Medical Center8

- Boston University4

- Takeda Pharmaceuticals4

- Massachusetts General Hospital4

Top Industries Hiring
- Healthcare & Medical Services
Clinical Program Manager Jobs in Boston: Frequently Asked Questions
How do I get a clinical program manager job in Boston?
Target the Longwood Medical Area first, where academic medical centers, research hospitals, and biopharma companies concentrate the highest volume of clinical program manager openings in the city. Candidates with experience managing IRB submissions, clinical trial operations, or value-based care programs stand out in Boston's market. A background at a teaching hospital or a CRO gives you a strong foothold with the employer types that dominate local hiring.
Which companies hire clinical program managers in Boston?
Companies currently hiring clinical program managers in Boston include Tufts Medical Center, Boston Medical Center, and Boston University, per current listings on Migrate Mate as of November 2026. Boston's employer mix skews heavily toward academic medical systems, specialty biopharma, and health-tech firms headquartered in the Seaport and Kendall Square corridors.
Are there remote clinical program manager jobs in Boston?
Yes, though availability depends heavily on the type of work: analytical, regulatory, and program coordination roles are frequently remote, while positions tied to clinical site oversight or patient-facing operations are usually on-site. About 63% of clinical program manager openings tied to Boston are remote or hybrid as of November 2026. Biopharma and health-tech firms in the Seaport tend to offer the most flexible arrangements.
How can I get a clinical program manager job in Boston with little or no experience?
The most realistic entry path in Boston is through a clinical coordinator or research administrator role at one of the Longwood Medical Area hospital systems, which regularly promote from within into program management. Boston's large academic medical centers also run formal program management training tracks. Volunteering or interning with a community health organization in neighborhoods like Roxbury or Jamaica Plain can build the local credibility that hiring managers notice.
Which industries hire the most clinical program managers in Boston?
The sectors hiring the most clinical program managers in Boston are Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. Boston's dense cluster of world-class research hospitals, biopharma headquarters, and health-tech startups makes it one of the most active markets in the country for this role.
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See All 57 Clinical Program Manager Jobs in Boston
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