Clinical Research Nurse Jobs in Baltimore, MD
Clinical Research Nurse jobs in Baltimore are concentrated across the city's medical research corridor, from East Baltimore's academic hospital complex to the Inner Harbor biotech cluster, with strong demand in oncology, cardiology, and phase trials. Employers hiring right now include Johns Hopkins University, Parexel, and The Johns Hopkins University. See the openings below and apply to the ones that match your experience.
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The Department of Neurology is seeking a Sr. Clinical Research Manager. Researchers at Johns Hopkins University conduct clinical trials and clinical studies to discover new ways to prevent and treat diseases and other health problems. The Sr. Clinical Research Manager works in collaboration with PI(s) to set the direction for research and is responsible for the overall management of a clinical trials portfolio and clinical research activities. Plans and directs clinical research operations which typically involves external partners and internal collaborators, and/or national and international networks. Responsible for managing research staff, developing and implementing effective data management and regulatory procedures, providing education to research staff, and ensuring research staff are properly trained.
Specific Duties & Responsibilities
- Collaborate with investigator(s) and exercise independent judgement in directing the conduct of the research
- Participate in scientific discussions with collaborators, PI's, and funding organizations and contribute to decisions impacting conduct of research.
- Responsible for the recruitment, education, training and supervision of the clinical research coordinators and regulatory personnel within the program.
- Responsible for development and implementation of policy and procedures for clinical research within the program.
- Facilitate effective teamwork among all involved personnel, e.g. research staff, research nursing, data management, regulatory personnel, hospital staff, etc.
- Ensure responsible conduct of clinical research protocols throughout the lifecycle, including development, implementation, maintenance, and termination.
- Collaborate with PIs on research protocol development and evaluation, including reviewing and assessing new protocols for clarity, thoroughness, financial and logistical feasibility, maintaining subject safety etc.
- Oversee preparation and submissions to IRB and act as liaison for regulatory issues on behalf of the PI.
- Track and oversee the regulatory approval process to ensure efficient study startup; assist regulatory staff with informed consent and protocol amendments for investigator-initiated studies
- Manage clinical research budget generation and financial management of the program.
- Ensure efficient use of centralized resources and adherence to policies as appropriate, e.g. clinical trial management system, prospective reimbursement analysis, etc.
- Analyze resource utilization by individual trials to ensure research needs are anticipated and met.
- Ensure adequate system for tracking and reporting clinical research milestones for financial invoicing.
- Ensure the development, testing, and evaluation of manuals, questionnaires, and coding structures for the efficient collection of data.
- Ensure research staff maintain complete and accurate research data and charts and are well prepared for auditing and monitoring visits.
- Lead study meetings to examine data, decide on next steps, implement changes to protocol operations based on results and goals, and initiate sub-studies.
- Contribute to manuscripts and presentations.
- Other duties as assigned.
Minimum Qualifications
- Bachelor's Degree in a related field.
- Six years of related experience in clinical research in an academic, government, or pharmaceutical industry environment.
- Demonstrated supervisory or lead experience.
- Advanced knowledge of GCP/ICH and local regulations.
- Additional education may substitute for required experience and additional related experience may substitute for required education beyond a high school diploma/graduation equivalent, to the extent permitted by the JHU equivalency formula.
Preferred Qualifications
- Master's Degree in a related field.
- Certification as a Clinical Research Professional.
- Formal project management training or certification.
Technical Skills & Expected Level of Proficiency
- Budget Management - Advanced
- Clinical Resource Knowledge - Advanced
- Data Management and Analysis - Advanced
- Good Clinical Practices - Advanced
- Finance Project Management - Advanced
- Oral and Written Communications - Advanced
- Program Development - Advanced
- Record Keeping - Advanced
- Regulatory Compliance - Advanced
- Resource Management - Advanced
- Strategic Program Management - Advanced
The core technical skills listed are most essential; additional technical skills may be required based on specific division or department needs.
Classified Title: Sr. Clinical Research Manager
Role/Level/Range: ACRP/04/ME
Starting Salary Range: $64,600 - $113,300 Annually ($89,000 targeted; Commensurate w/exp.)
Employee group: Full Time
Schedule: M-F 8:30 am - 5:00 pm
FLSA Status: Exempt
Location: Remote
Department name: SOM Neuro BIOS
Personnel area: School of Medicine
Total Rewards
The referenced base salary range represents the low and high end of Johns Hopkins University’s salary range for this position. Not all candidates will be eligible for the upper end of the salary range. Exact salary will ultimately depend on multiple factors, which may include the successful candidate's geographic location, skills, work experience, market conditions, education/training and other qualifications. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/.
Education and Experience Equivalency
Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines: JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
Applicants Completing Studies
Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
Background Checks
The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate's conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.
Diversity and Inclusion
The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.
Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
EEO is the Law
https://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12ScreenRdr.pdf
Accommodation Information
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit: https://accessibility.jhu.edu/.
Vaccine Requirements
Johns Hopkins University requires all faculty, staff, and students to receive the seasonal flu vaccine. Exceptions to the flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry.
The following additional provisions may apply, depending upon campus. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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Find Clinical Research Nurse JobsClinical Research Nurse Job Market in Baltimore
Who's Hiring
- Johns Hopkins University42

- Parexel4

- The Johns Hopkins University4

- Headlands Research3H
- University of Maryland, Baltimore2

Top Industries Hiring
- Education44
- Healthcare & Medical Services4
- Biotechnology & Pharmaceuticals4
- Consulting & Professional Services2
Clinical Research Nurse Jobs in Baltimore: Frequently Asked Questions
How do I get a clinical research nurse job in Baltimore?
The strongest entry point in Baltimore is targeting its academic medical centers and affiliated research institutes, which run the largest volume of sponsored clinical trials in the region. Candidates with Good Clinical Practice certification and experience in oncology or cardiology protocols stand out. Networking through Johns Hopkins Medicine and University of Maryland Medical System events, and focusing applications on East Baltimore and the biotech corridor near the Inner Harbor, gives you a practical local edge.
Which companies hire clinical research nurses in Baltimore?
Employers hiring clinical research nurses in Baltimore right now include Johns Hopkins University, Parexel, and The Johns Hopkins University, based on current listings on Migrate Mate as of July 2026. Baltimore's hiring is driven by a dense mix of academic medical systems, independent research sites, and contract research organizations with offices close to the city's major hospital campuses.
Are there remote clinical research nurse jobs in Baltimore?
Yes, but with significant limits since clinical research nursing is largely hands-on, requiring direct patient contact, specimen collection, and on-site protocol administration. About 85% of clinical research nurse openings tied to Baltimore are remote or hybrid as of July 2026, primarily covering study coordination, data review, and regulatory documentation tasks. Roles at contract research organizations with Baltimore-area sponsors tend to offer the most flexible arrangements.
How can I get a clinical research nurse job in Baltimore with little or no experience?
The most realistic entry path in Baltimore is applying to research coordinator or clinical trials assistant roles at the city's large academic medical systems, which regularly hire nurses transitioning from bedside care into research. University of Maryland Medical System and affiliated research institutes frequently post entry-level study coordinator positions that accept candidates with an active RN license and one to two years of clinical floor experience. Completing a Good Clinical Practice certification before applying strengthens your candidacy considerably.
Which industries hire the most clinical research nurses in Baltimore?
The sectors hiring the most clinical research nurses in Baltimore are Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of July 2026. Baltimore's concentration of federally funded academic medical centers, combined with a growing biotech presence near the Inner Harbor and along the I-270 corridor, keeps institutional research and life sciences as the dominant local employers for this role.
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