Senior Level Clinical Site Manager Jobs
Senior level clinical site manager jobs place experienced professionals in charge of site operations, study oversight, and the cross-functional teams that keep complex clinical trials on schedule. Roles are concentrated in Consulting & Professional Services, Technology & Software, and Healthcare & Medical Services, with a mix of on-site, remote, and hybrid opportunities, and employers like Cuhaci Peterson, Carollo Engineers, and Amazon hiring at this level now.
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Showing 5 of 212+ Senior Level Clinical Site Manager jobs
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
New to North Carolina. Known for pursuing breakthroughs in medicine.
Ready to join our team?
At AbbVie, we bring together talented people and innovative science to develop medicines that help patients. Now, we’re bringing that commitment to Durham, North Carolina, with a new manufacturing campus that will expand our ability to produce medicines and create opportunities in the Research Triangle.
The campus will integrate advanced manufacturing, laboratory technologies and AI to support the production of immunology, oncology and neuroscience medicines. The first phase will include manufacturing facilities, next-generation laboratories, a warehouse, administrative offices and employee wellness facilities.
To learn more about this investment, please visit https://www.abbvie.com/abbvie-north-carolina-manufacturing.html
We are now recruiting our Project Manager - Construction (Utilities & Site Infrastructure) as part of the core start up team.
In this role, you will:
- Utility systems will include Industrial Utilities (IU) and Clean Utilities (CU) including Domestic Water, Chilled Water, Condenser Water, Heating Hot Water, Plant Steam and Condensate, Electrical Distribution including UPS and Generator backup systems, Compressed Air, Process Waste, Sanitary Waste, Vacuum, Pre-Treated Water, Water for Injection (WFI), Gaseous Delivery (i.e., Nitrogen), Clean Steam, and Clean Compressed Air.
- Manages key design interfaces between SVP and BDS A&E firm(s) to ensure that the Basis of Design for both CU and IU systems are aligned including any pre-treatment steps that may be centralized.
- Manages key design interfaces between SVP and BDS A&E firm(s) and the Balance of Campus (BOC) A&E firm to ensure that clear system boundaries are established.
- In coordination with AbbVie's Startup and CQV group, ensure that utility system preparation for operation steps, i.e., pressure testing, cleaning, descaling, passivation, etc. is included for all CU and IU systems.
- Ensure up-front planning is established for handling feed and waste stream flows for typical utility system preparation for operation steps.
- Evaluate modularization of CU and IU systems during design to ensure that future expansion of utilty systems are accommodated.
- Evaluate skidded systems, off-site fabrication, pipe racks, etc. to ensure fastest installation and startup approach can be delivered.
- Ensure Industrial Use Permit (IUP) requirements for both domestic water inflow and sewer outflow is coordinated throughout the initial design process and that the site IUP is approved in advance of project requirements. Additionaly, ensure that any other environmental and/or permitting considerations are evaluated such as Active Pharmaceutical Ingredient (API) concentrations in effluent.
- Ensure that a common set of utility system engineering specfications and standards are established across the program.
- Establish third-party testing programs for all CU and IU systems and ensure that off-site testing, inspections, reporting, etc. is clearly defined prior to bidding those services.
- Align on long-lead equipment required for early procurement and ensure that equipment specifications and procurement packages are initiated as soon as practicable.
- Working with AbbVie EHS, align on sustainability and energy efficiency requirements as well as establishing a Power Monitoring System.
- Working with AbbVie BTS, ensure that control architecture is aligned for all utility systems.
- Evaluate constructability and sequence of all utility systems to ensure fastest possible beneficial use and qualified operational dates can be achieved.
- Working with the SVP and BDS A&E firm(s) and AbbVie leads for both, ensure that a clearly defined and delineated interface between utility system design scopes are established.
- Working with AbbVie EHS, ensure that safe work plans are established for construction, pre-startup, commissioning and qualification activities are establshed and aligned.
- Manages and controls budget for all utility systems scope.
- Manages and controls schedule for all utility systems scope.
- Manages and controls risk assessments and remediation for all utility systems scope.
Qualifications
You will have a Bachelor’s degree in engineering or a related technical discipline. with 7+ years industry experience with demonstrated experience in project execution and accountability, team and stakeholder influencing and strong communication skills
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Job Description
New to North Carolina. Known for pursuing breakthroughs in medicine.
Ready to join our team?
At AbbVie, we bring together talented people and innovative science to develop medicines that help patients. Now, we’re bringing that commitment to Durham, North Carolina, with a new manufacturing campus that will expand our ability to produce medicines and create opportunities in the Research Triangle.
The campus will integrate advanced manufacturing, laboratory technologies and AI to support the production of immunology, oncology and neuroscience medicines. The first phase will include manufacturing facilities, next-generation laboratories, a warehouse, administrative offices and employee wellness facilities.
To learn more about this investment, please visit https://www.abbvie.com/abbvie-north-carolina-manufacturing.html
We are now recruiting our Project Manager - Construction (Utilities & Site Infrastructure) as part of the core start up team.
In this role, you will:
- Utility systems will include Industrial Utilities (IU) and Clean Utilities (CU) including Domestic Water, Chilled Water, Condenser Water, Heating Hot Water, Plant Steam and Condensate, Electrical Distribution including UPS and Generator backup systems, Compressed Air, Process Waste, Sanitary Waste, Vacuum, Pre-Treated Water, Water for Injection (WFI), Gaseous Delivery (i.e., Nitrogen), Clean Steam, and Clean Compressed Air.
- Manages key design interfaces between SVP and BDS A&E firm(s) to ensure that the Basis of Design for both CU and IU systems are aligned including any pre-treatment steps that may be centralized.
- Manages key design interfaces between SVP and BDS A&E firm(s) and the Balance of Campus (BOC) A&E firm to ensure that clear system boundaries are established.
- In coordination with AbbVie's Startup and CQV group, ensure that utility system preparation for operation steps, i.e., pressure testing, cleaning, descaling, passivation, etc. is included for all CU and IU systems.
- Ensure up-front planning is established for handling feed and waste stream flows for typical utility system preparation for operation steps.
- Evaluate modularization of CU and IU systems during design to ensure that future expansion of utilty systems are accommodated.
- Evaluate skidded systems, off-site fabrication, pipe racks, etc. to ensure fastest installation and startup approach can be delivered.
- Ensure Industrial Use Permit (IUP) requirements for both domestic water inflow and sewer outflow is coordinated throughout the initial design process and that the site IUP is approved in advance of project requirements. Additionaly, ensure that any other environmental and/or permitting considerations are evaluated such as Active Pharmaceutical Ingredient (API) concentrations in effluent.
- Ensure that a common set of utility system engineering specfications and standards are established across the program.
- Establish third-party testing programs for all CU and IU systems and ensure that off-site testing, inspections, reporting, etc. is clearly defined prior to bidding those services.
- Align on long-lead equipment required for early procurement and ensure that equipment specifications and procurement packages are initiated as soon as practicable.
- Working with AbbVie EHS, align on sustainability and energy efficiency requirements as well as establishing a Power Monitoring System.
- Working with AbbVie BTS, ensure that control architecture is aligned for all utility systems.
- Evaluate constructability and sequence of all utility systems to ensure fastest possible beneficial use and qualified operational dates can be achieved.
- Working with the SVP and BDS A&E firm(s) and AbbVie leads for both, ensure that a clearly defined and delineated interface between utility system design scopes are established.
- Working with AbbVie EHS, ensure that safe work plans are established for construction, pre-startup, commissioning and qualification activities are establshed and aligned.
- Manages and controls budget for all utility systems scope.
- Manages and controls schedule for all utility systems scope.
- Manages and controls risk assessments and remediation for all utility systems scope.
Qualifications
You will have a Bachelor’s degree in engineering or a related technical discipline. with 7+ years industry experience with demonstrated experience in project execution and accountability, team and stakeholder influencing and strong communication skills
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our long-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
https://www.abbvie.com/join-us/reasonable-accommodations.html
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Find JobsSenior Level Clinical Site Manager Job Market
Who's Hiring
- Cuhaci Peterson13
- Carollo Engineers13
- Amazon12
- HDR9
- Sun River Health8
Top Industries Hiring
- Consulting & Professional Services54
- Technology & Software40
- Healthcare & Medical Services25
- Construction & Real Estate20
- Electronics & Hardware12
Senior Level Clinical Site Manager Jobs: Frequently Asked Questions
How do I get a senior level clinical site manager job?
Employers at this level look for candidates who have independently managed multi-site or high-complexity trials and can demonstrate clear ownership of outcomes, not just task completion. Highlighting your experience leading site selection, managing escalations, and mentoring junior staff gives you an edge. A strong regulatory compliance record and sponsor-facing communication skills are equally important at the senior level.
Which companies hire senior level clinical site managers?
Companies hiring senior level clinical site managers right now include Cuhaci Peterson, Carollo Engineers, and Amazon, based on current listings on Migrate Mate as of November 2026. Hiring at this level is led by contract research organizations, large pharmaceutical companies, and specialty biotech firms managing late-phase or multi-regional studies.
Are there remote senior level clinical site manager jobs?
Yes, though many roles still require periodic on-site presence at clinical trial locations. About 27% of senior level clinical site manager openings are remote or hybrid as of November 2026, reflecting how sponsors and CROs have expanded flexible arrangements for experienced professionals who can manage site relationships and documentation without being stationed locally full time.
What makes a clinical site manager role senior level?
Senior level roles carry broader scope and direct accountability for study outcomes across multiple sites or therapeutic areas. Candidates are expected to operate with minimal supervision, serve as the primary sponsor contact for escalations, lead or contribute to process improvement initiatives, and provide guidance to junior site managers. Technical depth in regulatory requirements and protocol deviations is assumed, not developed on the job.
Which industries hire the most senior level clinical site managers?
Senior Level clinical site manager roles concentrate in Consulting & Professional Services, Technology & Software, and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring because they operate the largest and most complex clinical development pipelines, requiring experienced managers who can oversee sites across multiple geographies and therapeutic areas simultaneously.