Flagship Pioneering Visa Sponsorship Jobs USA
Flagship Pioneering is a life sciences venture creation firm behind transformative companies including Moderna. For visa-seeking professionals in biotech investment and innovation strategy, the firm does sponsor work visas, making it a targeted but selective opportunity worth pursuing with preparation.
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Get Access To All JobsAbout Abiologics
Abiologics is a Flagship Pioneering company developing Synteins™ — a transformative class of fully synthetic proteins composed entirely of artificial building blocks such as D-amino acids and non-canonical residues. SynteinsTM are designed to transcend the limitations of traditional biologics, with improved oral stability, immune evasion, and metabolic durability — all while being fully programmable by design. Powered by a proprietary AI-enabled discovery platform, Abiologics integrates generative design, automated synthesis, and rapid experimental screening to enable iterative optimization at scale.
Position Summary
We are seeking a Protein Design Scientist to join the Computational Protein Design team and help drive structure-based design and optimization of synthetic proteins. This is a highly interdisciplinary role at the interface of computational design, structural biology, and protein engineering. Ideal candidates have deep experience in de novo protein design, miniproteins, and binders engineering and are eager to push the boundaries of non-natural protein design in a fast-moving, data-rich environment.
Key Responsibilities
- Design and execute SynteinsTM engineering campaigns to generate drug candidates.
- Create computational design strategies to deliver drug candidates drawing from array of ML tools and Rosetta scripts.
- Collaborate with computation, chemistry, and experimental biology teams to optimize designs for function, solubility, and stability.
- Integrate structural and biophysical data (e.g., binding, CD, HDX-MS, CryoEM) into iterative optimization cycles.
Qualifications
Required
- PhD in structural biology, biophysics, protein design, or related field
- 2+ years of hands-on experience in structure-guided protein design
- Demonstrated proficiency with modern structure prediction and design tools such as RFdiffusion, proteinMPNN, AF2, Boltz2, BoltzGen, Rosetta or equivalent SOTA tools for in-silico protein engineering.
- Strong understanding of the biophysics of protein folding and interface energetics
- Demonstrated ability to progress designs from concept to experimental testing
- Excellent communication skills
Preferred
- Experience designing minibinders or proteins
- Familiarity with non-canonical amino acid design
- Familiarity with molecular dynamics tools.
- Exposure to high-throughput or automated protein engineering environments
- Prior work on platform-based or early-stage biotech teams
Why Join Abiologics
- Help invent a new class of programmable synthetic proteins
- Be part of a high-velocity discovery platform with real-time synthesis and screening
- Collaborate with a deeply interdisciplinary, mission-driven team
- Redefine the limits of what proteins can do
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies:
Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants:
When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
About Abiologics
Abiologics is a Flagship Pioneering company developing Synteins™ — a transformative class of fully synthetic proteins composed entirely of artificial building blocks such as D-amino acids and non-canonical residues. SynteinsTM are designed to transcend the limitations of traditional biologics, with improved oral stability, immune evasion, and metabolic durability — all while being fully programmable by design. Powered by a proprietary AI-enabled discovery platform, Abiologics integrates generative design, automated synthesis, and rapid experimental screening to enable iterative optimization at scale.
Position Summary
We are seeking a Protein Design Scientist to join the Computational Protein Design team and help drive structure-based design and optimization of synthetic proteins. This is a highly interdisciplinary role at the interface of computational design, structural biology, and protein engineering. Ideal candidates have deep experience in de novo protein design, miniproteins, and binders engineering and are eager to push the boundaries of non-natural protein design in a fast-moving, data-rich environment.
Key Responsibilities
- Design and execute SynteinsTM engineering campaigns to generate drug candidates.
- Create computational design strategies to deliver drug candidates drawing from array of ML tools and Rosetta scripts.
- Collaborate with computation, chemistry, and experimental biology teams to optimize designs for function, solubility, and stability.
- Integrate structural and biophysical data (e.g., binding, CD, HDX-MS, CryoEM) into iterative optimization cycles.
Qualifications
Required
- PhD in structural biology, biophysics, protein design, or related field
- 2+ years of hands-on experience in structure-guided protein design
- Demonstrated proficiency with modern structure prediction and design tools such as RFdiffusion, proteinMPNN, AF2, Boltz2, BoltzGen, Rosetta or equivalent SOTA tools for in-silico protein engineering.
- Strong understanding of the biophysics of protein folding and interface energetics
- Demonstrated ability to progress designs from concept to experimental testing
- Excellent communication skills
Preferred
- Experience designing minibinders or proteins
- Familiarity with non-canonical amino acid design
- Familiarity with molecular dynamics tools.
- Exposure to high-throughput or automated protein engineering environments
- Prior work on platform-based or early-stage biotech teams
Why Join Abiologics
- Help invent a new class of programmable synthetic proteins
- Be part of a high-velocity discovery platform with real-time synthesis and screening
- Collaborate with a deeply interdisciplinary, mission-driven team
- Redefine the limits of what proteins can do
ABOUT FLAGSHIP PIONEERING:
Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.
We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your background and interest in Flagship.
Recruitment & Staffing Agencies:
Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.
The salary range for this role is $146,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Abiologics, Inc currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Abiologics, Inc's good faith estimate as of the date of publication and may be modified in the future.
Privacy Notice for Applicants:
When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.
Job Roles at Flagship Pioneering
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Get Access To All JobsTips for Finding Flagship Pioneering Visa Sponsorship Jobs USA
Target roles at the intersection of science and investment
Flagship sits between deep biotech R&D and venture capital strategy. Sponsored roles tend to require strong scientific credentials paired with business acumen. Focus your application on positions where those two skill sets overlap most clearly.
Lead with your H-1B eligibility early in the process
Flagship sponsors H-1B visas, but hiring teams at investment and innovation firms move quickly. Flagging your visa status and specialty occupation qualifications upfront helps hiring managers assess fit without delays late in the process.
Understand the specialty occupation standard for your role
H-1B sponsorship at firms like Flagship requires the role to qualify as a specialty occupation. Roles in biotech venture creation, scientific operations, and portfolio company strategy typically meet this bar when tied to an advanced degree field.
Position yourself for long-term immigration support including Green Cards
Flagship has sponsored both H-1B and Green Card pathways. If permanent residency matters to you, ask during the offer stage about the firm's track record supporting EB-2 or EB-3 filings for long-term hires.
Use Migrate Mate to identify verified sponsorship history before applying
Flagship is a selective sponsor, so confirming real visa activity before investing time in your application matters. Migrate Mate surfaces verified sponsors so you can filter by actual sponsorship history and apply with confidence.
Tailor your application to Flagship's venture creation model
Flagship doesn't operate like a traditional investment firm or a standard biotech employer. Highlighting experience with company formation, early-stage science commercialization, or platform biology research will resonate far more than generic finance or lab experience.
Frequently Asked Questions
Does Flagship Pioneering sponsor H-1B visas?
Yes, Flagship Pioneering sponsors H-1B visas. The firm operates at the crossroads of life sciences innovation and venture creation, and has sponsored H-1B petitions for qualified professionals in roles that meet the specialty occupation standard. Given the firm's selective hiring model, sponsored positions tend to require an advanced degree in a directly relevant scientific or business field.
What types of visas does Flagship Pioneering sponsor?
Flagship Pioneering sponsors both H-1B nonimmigrant visas and employment-based Green Cards, including EB-2 and EB-3 categories. This means the firm supports both initial work authorization and longer-term permanent residency pathways for qualifying employees. The combination makes Flagship a meaningful option for international professionals thinking beyond short-term work authorization.
Which roles or departments at Flagship Pioneering are most likely to receive visa sponsorship?
Sponsorship at Flagship Pioneering is most common in roles that blend deep scientific expertise with strategic or operational responsibilities, such as scientific affairs, venture development, and portfolio company operations. Given the firm's biotech focus, candidates with advanced degrees in biology, chemistry, or related fields pursuing roles that require that specialized knowledge are best positioned for sponsored positions.
How do I apply for a job at Flagship Pioneering as a visa-sponsored candidate?
Start by identifying open roles that match your specialty occupation qualifications. When you apply, be transparent about your visa status and timeline upfront. Flagship moves deliberately in hiring, so framing your H-1B or Green Card needs clearly from the first conversation avoids late-stage complications. Migrate Mate lets you browse Flagship's open roles filtered by confirmed sponsorship activity, so you can focus your effort on positions with real sponsorship potential.
How do I know if Flagship Pioneering is actively sponsoring visas right now?
Sponsorship activity at specialized investment and innovation firms like Flagship can shift based on hiring cycles and organizational growth. The most reliable way to gauge current activity is to look at recent sponsorship filings and open job data together. Migrate Mate aggregates verified sponsorship history alongside live job listings, so you can see whether Flagship is actively hiring sponsored roles at this moment rather than relying on outdated information.