Senior Level COO Jobs

Senior level coo jobs put experienced operators in charge of organizational direction, cross-functional execution, and the leadership teams that deliver results. Openings concentrate across Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Insurance, with 27% remote or hybrid availability, and employers like CVS Health, Revolution Medicines, and Cornerstone Caregiving hiring at this level now.

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Overview

Open roles255+
Top stateCalifornia
Top employerCVS Health
Top citySan Francisco, CA
Work type73% On-site
Top industryBiotechnology

Showing 5 of 255+ Senior Level COO jobs

Sephora
Director, HRBP Retail Operations
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Sephora
New 14h ago
Director, HRBP Retail Operations
Sephora
Remote
Human Resources
Corporate Training & Learning Development
$151k - $201k/yr
Remote (US)
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
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CVS Health
New 23h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Montpelier, Vermont
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
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CVS Health
New 23h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Harrisburg, Pennsylvania
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
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CVS Health
New 23h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Topeka, Kansas
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
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CVS Health
Added 1d ago
Lead Director - Security Operations Center (SOC)
CVS Health
Cheyenne, Wyoming
Account Management
Customer Service
Customer Support
$144k - $288k/yr
Bachelor's degree in information technology
10,000+

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Senior Level COO Job Market

Who's Hiring

  • CVS Health
    CVS Health20
  • Revolution Medicines
    Revolution Medicines13
  • Cornerstone Caregiving
    Cornerstone Caregiving8
  • Jobot
    Jobot6
  • Watson Institute
    Watson Institute5

Top Industries Hiring

  • Biotechnology & Pharmaceuticals37
  • Healthcare & Medical Services29
  • Insurance23
  • Technology & Software22
  • Consulting & Professional Services18

Senior Level COO Jobs: Frequently Asked Questions

How do I get a senior level coo job?

Employers hiring at the senior level want candidates who have led large cross-functional teams, owned P&L or operational outcomes, and driven measurable organizational change. Tailor your resume to show scope, not just responsibilities. Highlight initiatives you originated and the business results that followed. Board-level communication experience and a history of building leadership pipelines consistently give candidates an edge at this stage.

Which companies hire senior level coos?

Companies hiring senior level coos right now include CVS Health, Revolution Medicines, and Cornerstone Caregiving, based on current listings on Migrate Mate as of September 2026. Hiring at this level covers growth-stage companies seeking their first dedicated operations executive and established organizations replacing or elevating the role as they scale.

Are there remote senior level coo jobs?

Yes, though remote availability at this level is more selective than in individual-contributor roles. About 27% of senior level coo openings are remote or hybrid as of September 2026, reflecting demand from distributed companies and private equity-backed organizations that prioritize operator talent over geography. On-site roles remain common where the position requires daily presence across facilities or teams.

What makes a coo role senior level?

Senior level coo roles are defined by enterprise-wide ownership rather than departmental execution. Expectations include setting operational strategy, managing a team of directors or VPs, and partnering directly with the CEO and board. These roles carry accountability for organizational health, capital allocation decisions, and long-term scalability, distinguishing them from mid-level operations roles focused on process management within a single function.

Which industries hire the most senior level coos?

Senior level coo roles concentrate in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Insurance, based on current listings on Migrate Mate as of September 2026. These sectors tend to drive hiring at this level because rapid growth, regulatory complexity, or multi-site operations create a consistent need for dedicated operational leadership at the executive layer.