Director Head Of Jobs in Massachusetts
Director Head Of jobs in Massachusetts are open across Cambridge, Somerville, and Boston and other Massachusetts metros, with employers like Flagship Pioneering, Generate Biomedicines, and Leerink Partners LLC (Formerly Svb Securities Llc) hiring at every experience level. Find a role that fits below and apply directly.
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Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
- Physical and Emotional Wellness
- Financial Wellness
- Support for Caregivers
The Importance of the Role
Job Title: Head of New Product Strategy and Commercialization
Department: Commercial Operations
Reports to: VP, Commercial Operations
Location: Cambridge, MA
The Opportunity to Make a Difference
The Position:
The Head of New Product Strategy and Commercialization is responsible for the global commercial strategy of our pipeline of best-in-class siRNA assets. As the Head of New Product Strategy and Commercialization, you will co-lead the program Asset Team with an R&D co-lead accountable for shaping and advancing asset strategy in partnership with cross-functional peers. The individual must be able to drive timely, high-quality decisions, align diverse stakeholders across a complex matrix organization, and be accountable for recommendations and outcomes to executive management that impact the asset.
In your capacity as program Asset Co-Lead you will work across the portfolio and in partnership with the Global Brand Team, Global Development Team, Medical Affairs, Market Access, Commercial Operations, Clinical Development, and Patient Advocacy. For our later-stage assets, you will be accountable for actionable brand strategic and tactical plans to optimize launch readiness and commercial success, including disease awareness communications for multiple stakeholders, such as HCPs and patients/caregivers, to ensure market preparation.
This role also partners closely with Business Development to provide commercial assessments of external opportunities and support discussions on potential external partnerships.
Primary Responsibilities Include:
Head of New Product Strategy and Commercialization
- Own the asset strategic roadmap and long-term vision, ensuring commercial perspective is embedded in enterprise decision-making
- Be accountable for delivery of the asset objectives against corporate goals, including key strategic recommendations, trade-off decisions, and execution milestones
- Drive asset-level cross-functional decision-making by integrating functional input, resolving ambiguity, and escalating critical issues when needed
- Identify, assess, and elevate asset-level risks and opportunities, with clear ownership of mitigation strategies and decision follow-through
- Lead the development of target product profiles for pipeline assets, based on thorough understanding of market dynamics and potential future trends
- Partner with Market Access, Medical, and HEOR to build evidence and value strategies that support payer engagement and access for commercialization
- Partner with Commercial Operations and Manufacturing to develop integrated forecasts and market potential assessments
- Lead commercial assessments of potential therapeutic targets and programs
Desired Education and Skills:
- Bachelor’s degree with 15+ years or (MBA preferred with 13+ years) of experience in biotech/pharma strategic roles with a track record demonstrating accountability, sense of urgency and cross functional leadership
- Strong commercial acumen with significant experience in commercial strategy, brand marketing, brand strategy, and product management is required; global product launch experience in rare disease is preferred
- Extensive understanding of drug development and proven track record of using deep customer and market insight to deliver informed recommendations to R&D decisions that ensure attainment of commercial objectives
- Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
- Strong leadership abilities to influence and lead across a matrix environment, drive timely cross-functional decisions, and be accountable for asset-level recommendations and outcomes
- Experience in high science, competitive markets required
- Experience supporting business development through commercial opportunity assessment and due diligence, including evaluation of external assets, markets, and strategic fit
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
LI-Hybrid
This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time.
The targeted salary range for this position is $222,400 - $278,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
See All 7 Director Head Of Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Director Head Of JobsDirector Head Of Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Director Head Of Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Flagship Pioneering1

- Generate Biomedicines1

- Leerink Partners LLC (Formerly Svb Securities Llc)1

- Sarepta Therapeutics1

- SharkNinja1

Top Industries Hiring
- Science & Research3
- Biotechnology & Pharmaceuticals2
- Banking & Financial Services1
- Electronics & Hardware1
What Massachusetts Employers Look For
The qualifications that appear most often in director head of jobs across Massachusetts.
- 10 or more years of progressive experience in a relevant function or industry
- Demonstrated experience leading cross-functional or multi-team organizations
- Proven ability to build and execute strategic plans with measurable outcomes
- Experience managing budgets, headcount planning, and resource allocation
- Strong executive communication and stakeholder management skills
- Bachelor's degree required, with MBA or advanced degree often preferred
Director Head Of Jobs in Massachusetts: Frequently Asked Questions
How many director head of jobs are there in Massachusetts?
There are 7+ director head of openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Cambridge, Somerville, and Boston. New positions post regularly as employers across Massachusetts hire.
Which Massachusetts cities have the most director head of jobs?
Cambridge, Somerville, and Boston have the most director head of openings in Massachusetts right now, with additional roles spread across smaller metros statewide.
Which companies hire director head ofs in Massachusetts?
Employers hiring director head ofs in Massachusetts include Flagship Pioneering, Generate Biomedicines, and Leerink Partners LLC (Formerly Svb Securities Llc), based on current listings on Migrate Mate as of June 2026.
Are there remote director head of jobs in Massachusetts?
Yes. About 43% of director head of openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.
How do I apply for director head of jobs in Massachusetts?
You can apply to director head of jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.
See All 7 Director Head Of Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Director Head Of Jobs